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Biomarkers for the Early Detection of Pancreatic Ductal Adenocarcinoma

Pancreatic ductal adenocarcinoma has one of the worst survival rates among adult cancers, with only 11% in the United States surviving five years after diagnosis. The majority of patients are diagnosed with late-stage disease, since early-stage pancreatic ductal adenocarcinoma is typically either asymptomatic or presents with non-specific symptoms. Pancreatic ductal adenocarcinoma thus remains a h

The Class Dynamics of Ocean Grabbing : Who Are the ‘Fisher Peoples’?

Amidst processes of (uneven) dispossession and displacement of coastal populations—often termed ‘ocean grabbing’—scholar-activists, NGOs and the leadership of different social movements invoke, so-called, ‘fisher people’ as the political subjects of resistance. These ‘fisher people’ are often cast as capital's other as part of a normative and moral critique of ocean grabbing and purportedly the ag

CAVE : Connectome Annotation Versioning Engine

Advances in electron microscopy, image segmentation and computational infrastructure have given rise to large-scale and richly annotated connectomic datasets, which are increasingly shared across communities. To enable collaboration, users need to be able to concurrently create annotations and correct errors in the automated segmentation by proofreading. In large datasets, every proofreading edit

Elementary excitation in photosynthetic purple bacteria : How big is it?

We have studied excitation energy transfer in the photosynthetic antenna systems LH1 and LH2 of purple bacteria. Femtosecond pump-probe experiments were combined with computer simulations using the recently established structure of these systems to assess the nature of electronic excitation. We have measured the transient absorption kinetics and spectra of the LH1 and LH2 complexes in the temp

The adoption of the Swedish carbon tax : Influences and interactions across multiple political levels, jurisdictions, and policy areas

When Sweden adopted its carbon tax in 1990, it was as one of the first of its kind worldwide. While the adoption of the tax has been attributed to its inclusion in the Swedish tax reform, undoubtedly playing a crucial role, the reform does not in itself explain how the Swedish carbon tax came about or why it became part of the reform package in the first place. In this article, we present a case s

Time Trends and Sex Differences in the Invasive Treatment of Infrainguinal Intermittent Claudication in Sweden During 2009 – 2022 : Results From the Swedish Vascular Registry (Swedvasc)

Objective: This study aimed to report changes in the annual incidence of invasive treatment, changes in invasive treatment modalities, and sex differences in patients treated for intermittent claudication (IC) due to infrainguinal lesions in Sweden between 2009 and 2022. Methods: Data were collected from the Swedish Vascular Registry (Swedvasc), including all registrations of invasive treatment fo

Sex specific familial risk in lung cancer through changing histologies in Sweden

Familial clustering of lung cancer (LC) is related to shared smoking habits but the contribution of other potential factors such as sex or histology is not well known, and these are the subjects of the present study in Sweden. Family relationships (from Multigeneration register) and diagnosed cancers (from Cancer registry) were obtained from the national registers from 1961 to 2021. The overall fa

Quantum dots and quantum dot lattices : Correlations in small quantal systems

Recently, Attaccalite et al. proposed a new expression for the exchange-correlation energy of the two-dimensional electron gas, based on quantum Monte Carlo calculations. We compare this functional with the established expression given by Tanatar and Ceperley for use in density functional calculations. As model systems serve a circular few-electron quantum dot and a square lattice of dots. For sin

Rotational structure of T=0 and T=1 bands in the N=Z nucleus 62Ga

The rotational behavior of T=0 and T=1 bands in the odd-odd N=Z nucleus 62Ga is studied theoretically using the spherical shell model (laboratory frame) and the cranked Nilsson-Strutinsky model (intrinsic frame). Both models give a good description of available experimental data. The role of isoscalar and isovector pairing in the T=0 and T=1 bands as functions of angular momentum is studied in the

Known and less well-known comorbidities in axial spondyloarthritis : what are we overlooking? Results from the SPARTAKUS cohort

OBJECTIVES: To explore and compare the prevalences of a wide range of comorbidities in axial spondyloarthritis (axSpA) versus the general population, and in non-radiographic versus radiographic axSpA (nr-axSpA/r-axSpA).METHOD: Well-characterized axSpA patients (n = 246) from the SPARTAKUS cohort (55% men; mean age/disease duration 52/26 years; nr-axSpA/r-axSpA = 82/164) were included, and matched

Triaxiality in 48Cr

Rotational behavior inducing triaxiality is discussed for 48Cr in the cranked Nilsson-Strutinsky (CNS) model, as well as in the spherical shell model. It is shown that the low-spin region up to about 1 = 8, has a prolate well-deformed shape. At higher spins the shape is triaxial with a 'negative-γ' deformation, that is, with rotation around the classically forbidden intermediate axis. By comparing

Chaos assisted tunneling from superdeformed states

The tunneling process that governs the decay from superdeformed to normal-deformed nuclear states is shown to be enhanced by several orders of magnitude (104 – 106) if the normal-deformed states are chaotic at the moment of decay out. The onset of (long-range) chaos may imply that the tunneling enhancement increases with decreasing angular momentum. Experimental signatures are discussed.

Polarization effects in superdeformed nuclei

A detailed theoretical investigation of polarization effects in superdeformed nuclei is performed. In the pure harmonic oscillator potential it is shown that when one particle (or hole) with the mass single-particle quadrupole moment qν is added to a superdeformed core, the change of the electric quadrupole moment can be parameterized as qeff = e(bqν + a), and analytical expressions are derived fo

Decay-out from SD states initiated by the onset of chaos

It is shown that the decay out from superdeformed bands is enhanced by several orders of magnitude due to the onset of chaos in normal deformed states. The onset of chaos is caused by the residual two-body interaction, that plays a crucial role for the normal deformed states at excitation energies where the decay out occurs (3-5 MeV). At these excitation energies the distribution of nearest neighb

Band termination in the shell model

The mechanism of band termination is discussed from the spherical shell model point of view, and the role of breaking nucleon pairs within a given j-shell configuration is stressed. Two main types of band terminations are discussed. In one type the band termination includes a sequence of states within an approximative seniority coupling scheme and therefore is smooth. In the other type the termina

Deformed nuclear halos

Deformation properties of weakly bound nuclei are discussed in the deformed single-particle model. It is demonstrated that in the limit of a very small binding energy the valence particles in specific orbitals, characterized by a very small projection of single-particle angular momentum onto the symmetry axis of a nucleus, can give rise to the halo structure which is completely decoupled from the

Spherical proton emitters

Various theoretical approaches to proton emission from spherical nuclei are investigated, and it is found that all the methods employed give very similar results. The calculated decay widths are found to be qualitatively insensitive to the parameters of the proton-nucleus potential, i.e., changing the potential parameters over a fairly large range typically changes the decay width by no more than

Perioperative Risk Prediction in Head and Neck Free Flap Reconstructive Surgery

BACKGROUND: Extensive head and neck reconstructive surgery is a complex procedure often performed in patients with multiple comorbidities, and the risk of complications is high. Evidence-based preoperative assessment and reliable risk prediction are therefore essential, and the anesthesiologist plays an important role in this process. The aim of this study was to evaluate the predictive properties