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Inflammation without neuronal death triggers striatal neurogenesis comparable to stroke.

Ischemic stroke triggers neurogenesis from neural stem/progenitor cells (NSPCs) in the subventricular zone (SVZ) and migration of newly formed neuroblasts towards the damaged striatum where they differentiate to mature neurons. Whether it is the injury per se or the associated inflammation that gives rise to this endogenous neurogenic response is unknown. Here we showed that inflammation without c

Upper Cambrian (Furongian) biostratigraphy in Scandinavia revisited: definition of superzones

The traditional Furongian trilobite biozones of Scandinavia, recently proposed abandoned due to inconsistent boundary definitions [Terfelt, F., Eriksson, M.E., Ahlberg, P. & Babcock, L.E., 2008: Furongian Series (Cambrian) biostratigraphy of Scandinavia - a revision. Norwegian Journal of Geology88, 73-87], are resurrected and elevated to superzonal rank. These superzones are usually readily re

Gender and Transition in Climate Governance

This article demonstrates how gender is implicated in climate governance through insights derived from gender and transition studies in combination, applied and illustrated through a study of climate governance in Sweden. The approach is constructive and uses central analytical concepts: transition arenas, niches, regimes and landscapes together with insights from gender research. The article prop

Not by the Book: The Emergence and Translation of Housing First in Sweden

The emergence of Housing First in Sweden is described and analysed in the light of the deregulation of the housing market and the existing organisation of service delivery for homeless people. The spread and growth of Housing First in Sweden was promoted by Lund University during 2009. Although widely disseminated, implementation of Housing First has been slow. Only seven of Sweden’s 290 municipal

Bridging the accountability gap in hybrid organizations: The case of Malmö-Copenhagen Port

Abstract in UndeterminedPrevious research on hybrid organizations has drawn attention to the accountability gap that is believed to emerge when the provision of public services is transferred to a hybrid organization. In this article we take our point of departure in that research and use a case study method to explore whether this gap can be bridged by existing corporate governance systems or if

Prognostic Value of PAX-FKHR Fusion Status in Alveolar Rhabdomyosarcoma: A Report From the Cooperative Soft Tissue Sarcoma Study Group (CWS)

Background. Alveolar Rhabdomyosarcomas (RMA) are characterized by chromosomal translocations, fusing the PAX3 or PAX7 gene with FKHR in about 85%. Previous studies have suggested that the fusion type is associated with prognosis. In order to investigate the predictive value of the PAX-FKHR fusion status on disease outcome of patients with RMA treated in the CWS trials we performed a retrospective

Investigating the usefulness of satellite-derived fluorescence data in inferring gross primary productivity within the carbon cycle data assimilation system

Simulations of carbon fluxes with terrestrial biosphere models still exhibit significant uncertainties, in part due to the uncertainty in model parameter values. With the advent of satellite measurements of solar induced chlorophyll fluorescence (SIF), there exists a novel pathway for constraining simulated carbon fluxes and parameter values. We investigate the utility of SIF in constraining gross

Synthesis and crystal structure of a series of incommensurately modulated composite oxohalide compounds

Transparent, needle-like single crystals of the isostructural compounds [Sb4O7+3 delta X4][Zn-3](1+delta) = CL Br, I) delta approximate to 0.2 were obtained from chemical reactions in evacuated and sealed silica tubes. First, the average structure was solved in P211n but the model refined poorly and a lowering of the symmetry to the 3 + 1 dimensional space group P2(1)(alpha 0 gamma)0 gave a signif

Iron Age migration on the island of Öland : Apportionment of strontium by means of Bayesian mixing analysis

Migration is a complex subject to approach in archeology and the new materials and methods available, such as isotope analysis and DNA, make it possible, and necessary, to ask new questions. The objective of this paper is to highlight the possibilities with using a new approach to migration on a population level by applying Bayesian mixing analysis of strontium isotopes. The selected case, the isl

Review of LCA studies of solid waste management systems - Part I: Lessons learned and perspectives.

The continuously increasing solid waste generation worldwide calls for management strategies that integrate concerns for environmental sustainability. By quantifying environmental impacts of systems, life cycle assessment (LCA) is a tool, which can contribute to answer that call. But how, where and to which extent has it been applied to solid waste management systems (SWMSs) until now, and which l

Motor function after selective dorsal rhizotomy: a 10-year practice-based follow-up study.

Aim The aim of this study was to explore changes in motor function up to 10 years after selective dorsal rhizotomy (SDR). Method The participants comprised 29 children (20 males, nine females) with bilateral spastic diplegia who were consecutively operated on at a median age of 4 years and 3 months and followed until a median age of 15 years. SDR was combined with physiotherapy and regular follow-

Condensation and decondensation of DNA by cationic surfactant, spermine, or cationic surfactant-cyclodextrin mixtures: macroscopic phase behavior, aggregate properties, and dissolution mechanisms.

The macroscopic phase behavior and other physicochemical properties of dilute aqueous mixtures of DNA and the cationic surfactant hexadecyltrimethylammounium bromide (CTAB), DNA and the polyamine spermine, or DNA, CTAB, and (2-hydroxypropyl)-β-cyclodextrin (2HPβCD) were investigated. When DNA is mixed with CTAB we found, with increasing surfactant concentration, (1) free DNA coexisting with surfac

The diffusion of fired bricks in Hellenistic Europe : a similarity network analysis

In this study, similarity networks are used to analyse the diffusion of fired bricks across Hellenistic Europe, initiated in the north Aegean in the fourth century BCE. In a similarity network, archaeological contexts with similar attributes are connected according to a predefined criterion, and the edges are interpreted as potential social or causal links. Here we allow any kind of similarity rel

Use of ENCODE Resources to Characterize Novel Proteoforms and Missing Proteins in the Human Proteome

We describe integrated strategies that employ both translation of ENCODE data and major proteomic technology pillars to improve the identification of the missing proteins, protein isoforms, and PTMs. The results from proteoENCODEdb searches with experimental mass spectral data indicate that some novel splice forms detected at the transcript level are in fact translated to proteins. Our results pro

Induction of morphological changes in death-induced cancer cells monitored by holographic microscopy.

We are using the label-free technique of holographic microscopy to analyze cellular parameters including cell number, confluence, cellular volume and area directly in the cell culture environment. We show that death-induced cells can be distinguished from untreated counterparts by the use of holographic microscopy, and we demonstrate its capability for cell death assessment. Morphological analysis

Input/Output Stabilization in the General Two-Sided Model Matching Setup

The problem of input-output stabilization in a general two-sided model matching setup is studied. As a first step, the problem is reduced to a pair of uncoupled bilateral Diophantine equations over RH infinity. Then, recent results on bilateral Diophantine equations are exploited to obtain a numerically tractable solution given in terms of explicit state-space formulae. The resulting solvability c