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Internal fixation of femoral neck fractures in Parkinson's disease. 32 patients followed for 2 years

32 patients, suffering from Parkinson's disease, had internal fixation of femoral neck fractures. In 24 displaced fractures, 6 nonunions and 3 segmental collapses were seen; and in 8 undisplaced fractures, 1 case of segmental collapse was diagnosed. Healing complications were thus seen in one third. Total hip replacement for healing complication was performed in 3 of 32 patients. 9 patients died w

Temporal Aspects of High-Intensity Laser-Matter Interactions

Popular Abstract in Swedish Utvecklingen av laserpulser med extremt hög intensitet har försett forskare med ett verktyg som gör det möjligt att studera vad som händer då dessa pulser växelverkar med olika slags materia. Då växelverkan sker med en gas kan till exempel ultrakorta pulser från ultraviolett till röntgenområdet genereras som övertoner till laserpulsen. Dessa övertoner kan göras kortare The availability of short-pulse, high-intensity lasers has opened doors to new areas in atomic and plasma physics. The short pulses (a few femtoseconds), that are available today, enable unprecedented temporal measurements, while the high peak power accessible (several terawatts) allows physicists to study the interaction between light and relativistic plasmas. The aim of this work was twofold: i)

Partial resistance to malonate-induced striatal cell death in transgenic mouse models of Huntington's disease is dependent on age and CAG repeat length

Transgenic Huntington's disease (HD) mice, expressing exon 1 of the HD gene with an expanded CAG repeat, are totally resistant to striatal lesion induced by excessive NMDA receptor activation. We now show that striatal lesions induced by the mitochondrial toxin malonate are reduced by 70-80% in transgenic HD mice compared with wild-type littermate controls. This occurred in 6- and 12-week-old HD m

Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1 beta, but not by TNF-alpha

Synthesis of the antimicrobial protein neutrophil gelatinase-associated lipocalin (NGAL) increases dramatically in bronchial epithelial cells and alveolear type II pneumocytes during lung inflammation. IL-1beta induces a >10-fold up-regulation of NGAL expression in the type II pneumocyte-derived cell line A549 cells, whereas TNF-alpha, IL-6, and LPS had no effect. Similar IL-1beta selectivity was

Genome-wide structural and functional protein characterization by ab initio protein structure prediction

Popular Abstract in Swedish Många av alla kemiska processer som pågår i våra kroppar utförs av proteiner. När de inte fungerar blir vi sjuka. I vissa fall, till exempel vid Alzheimers sjukdom eller Creutzfeld Jacobs sjukdom, beror det på att ett visst protein har fel form. Att förstå hur proteiner antar sin slutliga form och vad det har för inverkan på proteinets funktion är således viktigt. ÅVery little is known about a considerable part of all proteins and it is time consuming and expensive to study each individual protein to determine its function, structure and cellular role. Proteins retain structural, functional and sequential characteristics from ancestral proteins and hence two proteins that share a common ancestor, i.e. are homologs, will to some extent have similar sequen

Mixed solutions of hydrophobically modified graft and block copolymers

Phase separation temperatures and viscosities of dilute and semidilute aqueous mixtures of hydrophobically modified graft and block copolymers have been studied. The graft copolymer was hydrophobically modified ethyl(hydroxyethyl)cellulose (HM-EHEC), and the block copolymers were hydrophobically modified poly(ethylene glycol) (HM-PEG) with diblock (DB) or triblock (TB) structures, i.e., modified a

Validation of the Brush Model towards VTI-measurement data recorded at Hällered 2005

The report shows a validation of the brush tire-model towards measurement data performed in the RFE-project within the IVSS-framework. The data is recorded by VTI at Volvos test track, Hällered. The winter tire, Continental ContiWinterContact TS810 215/55R16 and the summer tire, Continental ContiSportContact 225/45R17 91W are tested longitudinally and laterally at different conditions. A study of

Separate versus simultaneous saccharification and fermentation of two-step steam pretreated softwood for ethanol production

In two previous studies, optimal conditions were identified for two-step steam pretreatment Of SO2- and H2SO4-impregnated softwood. In the present study the yield of sugar and ethanol was determined in a process development unit where pretreatment was performed in a 10-L reactor and simultaneous sacchatification and fermentation (SSF) or enzymatic hydrolysis (EH) were performed in 30-L reactors. T

ACTH lowers serum lipids in steroid-treated hyperlipemic patients with kidney disease

The mechanisms behind secondary hyperlipidemia in patients with various chronic inflammatory diseases are not known in detail. We have recently demonstrated that ACTH exerts strong hypolipidemic effects in healthy volunteers. To test the clinical relevance of this finding, we administrated ACTH during three weeks to nine hyperlipidemic steroid-treated patients with kidney disease. Before administr

Individualized low-dose growth hormone (GH) treatment in GH-deficient adults with childhood-onset disease: metabolic effects during fasting and hypoglycemia

Growth hormone (GH) has insulin-antagonistic effects, and GH secretion is augmented during fasting and hypoglycemia. In the present study, 10 patients aged 21 to 28 years with childhood-onset GH deficiency (GHD) were studied during a 24-hour fast and a hypoglycemic glucose clamp before and after 9 months of GH replacement. During the 24-hour fast, blood glucose, serum insulin, and serum free fatty

Europeanisation, Territoriality and Political Time

In European governance, elements from different administrative and political cultures coalesce into one more complex framework. To capture some of the complexity, two central dimensions are addressed: territoriality and political time, understood as horizon, resource, and process. When investigating European governance the question of the institutional organization is important, since it relates t

The Swedish ankle arthroplasty register - An analysis of 531 arthroplasties between 1993 and 2005

Background Whether or not ankles can be replaced with reasonable safety has been the subject of debate. We present the results of a nationwide series of total ankle arthroplasties. Patients and methods All Swedish hospitals that implant or have implanted modern three-component ankle prostheses reported demographic data and date of index and revision surgery to a central register. After the data ha

Kinematics and Ultraviolet to Infrared Morphology of the Inner Homunculus of η Carinae

We present the first ultraviolet and optical images of η Car and itscircumstellar Homunculus nebula, obtained with the Advanced Camera forSurveys/High Resolution Camera (ACS/HRC) on board the Hubble SpaceTelescope (HST). Compared to those at visual wavelengths, UV imagesreveal excess emission 0.1"-0.6" from the central source along the minoraxis that may emanate from the outer parts of η Car's non