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The trigeminovascular system plays a central role in migraine, a condition in need of new treatments. The neuropeptide, calcitonin gene-related peptide (CGRP), is proposed as causative in migraine and is the subject of intensive drug discovery efforts. This study explores the expression and functionality of two CGRP receptor candidates in the sensory trigeminal system.
The diffusion of mobile phones in low- and middle-income countries has taken place faster than any other infrastructural development. Mobile Midwife, a mobile application implemented in Ghana in 2010, sends timely messages in local languages to registered expectant mothers and new parents. The field of mobile health (mHealth) is severely underresearched, yet it can be an alternative for improving
Abstract People with psychiatric disabilities (PD) are a vulnerable group, and should be offered support and rehabilitation when needed. Day centres that provide individually matched daily occupations are an important link to provide that. The present study aimed at gaining knowledge regarding the occupations performed in day centres, in terms of the participants' descriptions of what they were do
Cassava peels were pre-treated with alkali, enzyme and in sequential combination of alkali and enzyme, and used for production of bioethanol or biogas, or both (in sequence, bioethanol followed by biogas). The Biogas Endeavour and Automatic Methane Potential Test Systems were used for production of bioethanol and biogas, respectively. The bioethanol yield and volumetric productivity achieved with
Background: Activating KRAS mutations are common in ovarian carcinomas of low histological grade, less advanced clinical stage and mucinous histological subtype, and form part of the distinct molecular alterations associated with type I tumors in the dualistic model of ovarian carcinogenesis. Here, we investigated the occurrence, clinicopathological correlates and prognostic significance of specif
Horismenus parasitoids are an abundant and understudied group of eulophid wasps found mainly in the New World. Recent surveys based on morphological analyses in Costa Rica have quadrupled the number of named taxa, with more than 400 species described so far. This recent revision suggests that there is still a vast number of unknown species to be identified. As Horismenus wasps have been widely des
The available energy (AE), driving the turbulent fluxes of sensible heat and latent heat at the earth surface, was estimated at four partly complex coniferous forest sites across Europe (Tharandt, Germany; Ritten/Renon, Italy; Wetzstein, Germany; Norunda, Sweden). Existing data of net radiation were used as well as storage change rates calculated from temperature and humidity measurements to final
Kangaroo Care (KC) is an evidence-based nursing practice with many benefits for infants and parents. The purpose of this study was to describe parents' experience of information and communication mediated by staff nurses before and during KC at neonatal wards.
This study reports on the performance of two medium-range streamflow forecast models: (1) a multilayer feed-forward artificial neural network; and (2) a distributed hydrologic model. Quantitative precipitation forecasts were used as input to both models. The Furnas Reservoir on the Rio Grande River was selected as a case study, primarily because of the availability of quantitative precipitation fo
There is an overlap regarding Pittsburgh compound B (PIB) retention in patients clinically diagnosed as Alzheimer's disease (AD) and non-AD dementia. The aim of the present study was to investigate whether there are any differences between PIB-positive and PIB-negative patients in a mixed cohort of patients with neurodegenerative dementia of mild severity regarding neuropsychological test performa
We consider the problem of sparse modeling of a signal consisting of an unknown number of exponentially decaying sinusoids. Since such signals are not sparse in an oversampled Fourier matrix, earlier approaches typically exploit large dictionary matrices that include not only a finely spaced frequency grid but also a grid over the considered damping factors. The resulting dictionary is often very
När källsorterat matavfall från hushållen rötas i en biogasanläggning av modellen omrörd tank behövs en förbehandling för att göra materialet pumpbart och ta bort orenheter. En typ av förbehandling innebär att avfallet passerar genom en skruvpress som delar avfallet i en pumpbar fraktion och en torr fraktion, så kallat rejekt. På NSR förbehandlas matavfallet med denna teknik och rejektet skickas i
An overview of the integration of the Skåne provinces in the Swedish state after 1658.
Researchers examining self-esteem functioning typically consider self-esteem either an affective or competence related trait. However, to capture more precisely the role of self-esteem in behavior we need to view self-esteem both as something people hold and as something they strive for, and determine the relation between these aspects. In the present study the consequences of the dynamic interpla
Background: Caloramator celer is a strict anaerobic, alkalitolerant, thermophilic bacterium capable of converting glucose to hydrogen (H2), carbon dioxide, acetate, ethanol and formate by a mixed acid fermentation. Depending on the growth conditions C. celer can produce H2 at high yields. For a biotechnological exploitation of this bacterium for H2 production it is crucial to understand the factor
Popular Abstract in Swedish Systemiska biomarkörer hos patienter med aortaaneurysm. Kroppspulsådern eller aorta är huvudstammen som för syrerikt blod från hjärtat till perifera delar av kroppen. Kroppspulsåderbråck (aneurysm) i buken kännetecknas av försvagning i kärlväggen som i sin tur leder till vidgning av kroppspulsådern. Aneurysm är fyra gånger vanligare hos män än hos kvinnor över 65 års ålAbdominal aortic aneurysm (AAA) develops in 3-6% of the population over 65 years and affects mainly men. AAA has a complex etiology involving inflammation, proteolysis, fibrinolysis and coagulation. The general aim of the present thesis was to study the associations between markers of inflammation, proteolysis, fibrinolysis and coagulation with aneurysm size and growth. In paper I associations bet
Background: Prior reports suggest a link between gonadotropin-releasing hormone (GnRH) and gastrointestinal function. The aim of the study was to prospectively investigate women subjected to in vitro fertilization (IVF) using the GnRH analog buserelin, taking into account gastrointestinal symptoms and antibody development against buserelin, GnRH, luteinizing hormone (LH), and their receptors. Meth
