Bacteria utilize complement regulators as a means of evading the host immune response. Here, we describe protocols for evaluating the role vitronectin acquisition at the bacterial cell surface plays in resistance to the host immune system. Flow cytometry experiments identified human plasma vitronectin as a ligand for the bacterial receptor outer membrane protein H of Haemophilus influenzae type f.

This paper assesses a discussion on how to understand the relationship between Husserl’s Cartesian way and the later ontological way to the transcendental reduction: Is the Cartesian way flawed to the extent that the ontological way constitutes a principal correction to it, or is the ontological way a logical completion of an insufficient but nonetheless necessary Cartesian way? A reading with the

Dihadron and isolated direct photon-hadron angular correlations are measured in p+p collisions at s=200 GeV. The correlations are sensitive to nonperturbative initial-state and final-state transverse momenta kT and jT in the azimuthal nearly back-to-back region Δφ∼π. To have sensitivity to small transverse momentum scales, nonperturbative momentum widths of pout, the out-of-plane transverse-moment

We address the fundamental question why we should use PageRank and similar link-based algorithms in search engines, if at all. In a legendary article from 1998, the Google founders gave an intriguing wisdom-of-crowds justification for PageRank according to which the latter tracks quality online. This striking suggestion stands in contrast to the view that PageRank merely tracks what is popular. Ho

Obesity is a major threat to global health and metabolically associated with glycerol homeostasis. Here we demonstrate that in human adipocytes, the decreased pH observed during lipolysis (fat burning) correlates with increased glycerol release and stimulation of aquaglyceroporin AQP10. The crystal structure of human AQP10 determined at 2.3 Å resolution unveils the molecular basis for pH modulatio

Aims: We assessed the changes in short- and long-term outcomes and their relation to implementation of new evidence-based treatments in all patients with non-ST-elevation myocardial infarction (NSTEMI) in Sweden over 20 years. Methods and results: Cases with NSTEMI (n = 205 693) between 1995 and 2014 were included from the nationwide Swedish Web-System for Enhancement and Development of Evidence-B

Microstructure evolution in magnetic materials is typically a non-local effect, in the sense that the behaviour at a material point depends on the magnetostatic energy stored within the demagnetisation field in the entire domain. To account for this, we propose a finite element framework in which the internal state variables parameterising the magnetic and crystallographic microstructure are treat

Chronic obstructive pulmonary disease (COPD) is a debilitating respiratory disease and one of the leading causes of morbidity and mortality worldwide. It is characterized by persistent respiratory symptoms and airflow limitation due to abnormalities in the lower airway following consistent exposure to noxious particles or gases. Acute exacerbations of COPD (AECOPD) are characterized by increased c

Immunophenotypic characterization and molecular analysis have long been used to delineate heterogeneity and define distinct cell populations. FACS is inherently a single-cell assay, however prior to molecular analysis, the target cells are often prospectively isolated in bulk, thereby losing single-cell resolution. Single-cell gene expression analysis provides a means to understand molecular diffe

In this paper, we present the findings of a Universitas 21 (U21) Graduate Research Project collaboration between Pontificia Universidad Católica de Chile, the University of Nottingham, England, and Lund University, Sweden. This project brought together six doctoral candidates at various stages in their postgraduate careers. The students had conducted qualitative and quantitative inquiry into diver

The aim of this study was to explore parents’ experiences of sleep and rest while admitted to hospital together with their ill child. When a child is hospitalized, it can be a traumatic experience for the entire family. Adaptation to the new situation and new parental responsibilities is necessary. Hospitalized children demand more supervision and care, making sleep disturbance a common challenge

The effect of combustion on a gliding arc (GA) discharge is investigated using simultaneous measurements of current and voltage waveforms, as well as imaging and spectroscopic analysis of plasma and flame luminescence. Attributed to the existence of flame, the breakdown voltage and current peak are reduced and the bright sparks during breakdown are dampened. The intrinsic reason is largely owing t

Omkring 1080 påbörjades den ännu stående kyrkan. Arbetet utfördes sannolikt till stor den av slavarbetskraft, stenen kom från Hallaröd/Munkarpområdet och kördes längs en väg, vars spår ännu syns i landskapet. En stor del av artikeln behandlar slavar, slavhandel och slavsamhälets upphörande den därmed sammanhängande kolonisationen av Skånes allmänningsskogar

Allelopathy in bryophytes shapes ecosystems by influencing the species composition of both vascular plants and other bryophytes. Several allelopathically active chemicals in bryophytes have been discovered since the latter half of the 20th century and laboratory studies have showed their inhibiting impact on germination, growth and establishment of surrounding plants. However, other studies failed

Ozone oxidation of organic micropollutants in biologically treated wastewater was investigated in pilot-scale after a high- and a low loaded activated sludge process. Higher ozone doses were required to remove organic micropollutants in the effluent wastewater from the high loaded activated sludge process. Further comparison of the micropollutant removal was based on normalized ozone doses, expres

Liquid-liquid flow regimes in three square microchannels were visualized simultaneously both at the cross-shaped junction and in the microchannel “far” from the junction in order to reveal flow regime evolutions along the microchannel. At the inlet junction, three major flow regimes including tubing/threading, dripping and jetting were mapped using the aqueous capillary number versus the organic W