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Effects on weight gain and gut microbiota in rats given bacterial supplements and a high-energy-dense diet from fetal life through to 6 months of age

The aim of this study was to assess the long-term effects of a high-energy dense diet, supplemented with Lactobacillus plantarum (Lp) or Escherichia coli (Ec) on weight gain, fattening and the gut microbiota in rats. Since the mother’s dietary habits can influence offspring physiology, the dietary regimes started with the dams at pregnancy and through lactation, and continued with the offspring fo

University professors and early stage research commercialisation: an empirical test of the knowledge corridor theory

In this study, we test the knowledge corridor theory as an explanation of university professors' involvement in the early stages of research commercialisation. A statistical analysis was made of a sample of full professors from the engineering, natural sciences and medical faculties at a large public university in Sweden. The analysis shows that not only entrepreneurial experience but also private

Flexible sample environment for high resolution neutron imaging at high temperatures in controlled atmosphere.

High material penetration by neutrons allows for experiments using sophisticated sample environments providing complex conditions. Thus, neutron imaging holds potential for performing in situ nondestructive measurements on large samples or even full technological systems, which are not possible with any other technique. This paper presents a new sample environment for in situ high resolution neutr

Multi-scale characterization of pore evolution in a combustion metamorphic complex, Hatrurim basin, Israel: Combining (ultra) small-angle neutron scattering and image analysis

Backscattered scanning electron micrograph and ultra small- and small-angle neutron scattering data have been combined to provide statistically meaningful data on the pore/grain structure and pore evolution of combustion metamorphic complexes from the Hatrurim basin, Israel. Three processes, anti-sintering roughening, alteration of protolith (dehydration, decarbonation, and oxidation) and crystall

Dynamic Contrast-Enhanced MR Imaging for Differentiation of Rounded Atelectasis From Neoplasm

Purpose: To characterize rounded atelectasis (RA) with dynamic contrast-enhanced MRI in the differential diagnosis of solitary peripheral pulmonary neoplasm. Materials and Methods: Twenty-four patients with diagnostically equivocal peripheral pulmonary nodules were examined with dynamic contrast-enhanced MRI. 13 patients had a total of 16 rounded atelectases and 11 had a neoplasm. The final diagno

Is there evidence for post-translational modification of beta cell autoantigens in the aetiology and pathogenesis of type 1 diabetes?

Størling and colleagues hypothesise in this issue (Diabetologia DOI: 10.1007/s00125-013-3045-3 ) that post-translational modification (PTM) of autoantigens might create tissue-specific neo-epitopes that could trigger type 1 diabetes. Data on PTM of islet autoantigens are scarce and readers should not believe that the PTM hypothesis is supported by strong experimental evidence. The proposed genetic

NK cell development and function - Plasticity and redundancy unleashed.

Bone marrow-derived natural killer (NK) cells constitute the major subset of cytotoxic lymphocytes in peripheral blood. They provide innate defense against intracellular infection or malignancy and contribute to immune homeostasis. Large numbers of NK cells are also present in tissues, including the liver and uterus, where they can mediate immunosurveillance but also play important roles in tissue

Underwater endoscopic mucosal resection of large colorectal lesions.

In this prospective study, 11 consecutive patients with neoplastic colorectal lesions (median size 20 mm, range 15 - 25 mm) underwent endoscopic polyp removal by underwater endoscopic mucosal resection (EMR). Six lesions were removed en bloc and five lesions were removed by piecemeal resection. Pathological examination revealed seven R0 resections, and in four cases the pathology could not be dete

pH preferences of red-listed gasteromycetes in calcareous sandy grasslands: Implications for conservation and restoration

Species diversity in sandy grasslands is threatened by decalcification and eutrophication. To determine the most appropriate conditions for red-listed gasteromycete fungi in such grasslands, we investigated their pH preferences in this habitat in southern Sweden. During two winters soil samples were collected from the vicinity of mycelia of these species. Chemical analysis revealed that none of th

Rodent models of impulsive compulsive behaviors in Parkinson's disease: how far have we reached?

There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of behavioral addictions, which have been clinically defined as impulsive compulsive behaviors (ICBs). These features include pathological gambling, compulsive sexual behavior, binge eating, compulsive shopping, excessive hobbyism or punding, and the excessi

Biases in News Media as Reflected by Personal Pronouns in Evaluative Contexts

In this paper, we study whether pronouns in news media are used in evaluative contexts reflecting psychological biases. The evaluative contexts of pronouns are measured by computerized sentiment analysis, enabling analyses of large text corpora and subtle evaluative differences in how words are used in contexts. The results show that self-inclusive personal pronouns (We, I) occur in more positive

Quality indicators for palliative and end of life care: a review of Swedish policy documents.

All patients with palliative and end of life care needs should be guaranteed equal and safe treatment and care, regardless of their disease or site of care. The inclusion of quality indicators in national guidelines and other guiding documents supports quality assurance and improvement in provision of care. The aim of this paper was to review existing quality indicators in national Swedish policy

Plant-based vaccines: novel and low-cost possible route for mediterranean innovative vaccination strategies.

A plant bioreactor has enormous capability as a system that supports many biological activities, that is, production of plant bodies, virus-like particles (VLPs), and vaccines. Foreign gene expression is an efficient mechanism for getting protein vaccines against different human viral and nonviral diseases. Plants make it easy to deal with safe, inexpensive, and provide trouble-free storage. The b

Salespeople's value creation roles in customer interaction : An empirical study

Researchers have called for the need to investigate the salesperson's role in customer value creation in the context of companies moving into service and solution businesses. Despite the indisputable importance of the sales function in the company's customer relationships and in value creation for these customers, relevant literature has not yet answered the question of what salespeople actually d

Primary health care resources for rehabilitation and secondary prevention after myocardial infarction - a questionnaire survey.

Primary health care resources for rehabilitation and secondary prevention after myocardial infarction - a questionnaire survey Background: During the first year after a cardiac event, many patients are offered participation in a cardiac rehabilitation programme, after which the patients are often not given the opportunity to continue to attend rehabilitation and secondary prevention programmes. Ai

Higher Cathepsin B Levels in Plasma in Alzheimer's Disease Compared to Healthy Controls

Cathepsin B is suggested to be involved in amyloid-beta (A beta) processing and Alzheimer's disease (AD). Studies of cathepsin B levels in plasma and cerebrospinal fluid (CSF) have not been previously performed. We examined cathepsin B levels in plasma and CSF samples in persons with AD, mild cognitive impairment (MCI), and healthy controls in order to test the hypothesis that cathepsin B levels c