Background: The clinical benefit of combining long-acting beta(2)-agonists with inhaled corticosteroids rather than doubling the dose of corticosteroid has been well-documented. However, there are concerns that this might result in a masking of underlying airway inflammation. Objective: The aim of this study was to test the hypothesis that the addition of the long-acting beta(2)-agonist salmeterol

Some of the compounds used for density gradient separation of blood cells have high osmolarities at the concentrations needed to create the required specific densities. Several mixed media use a combination of hyperosmolar shrinkage and red cell aggregation to improve cell separation. Due to the characteristics of Percoll density gradient medium the density and osmolarity of the gradient can be co

Forty isoniazid-resistant Mycobacterium tuberculosis isolates were characterized on the basis of phenotypic properties (i.e., catalase activity, MIC of isoniazid, and growth pattern in the presence of 7 different concentrations of isoniazid) and alterations in the katG gene (codons 315 and 463). Three different growth patterns could be distinguished: concentration-dependent inhibition of growth wa

The capability of wood-rotting fungi (WRF) to colonise contaminated soil is an important fungal characteristic in the development of WRF-based soil bioremediation, it is also important to have methods that monitor the presence of the WRF in the soil. In this lab-scale study, it was shown that it was possible to re-capture, localise and identify a brown-rot fungus, Antrodia vaillantii, after it has

Perlecan is a heparan-sulfate proteoglycan abundantly expressed in pericellular matrices and basement membranes during development. Inactivation of the perlecan gene in mice is lethal at two developmental stages: around E10 and around birth. We report a high incidence of malformations of the cardiac outflow tract in perlecan-deficient embryos. Complete transposition of great arteries was diagnosed

Biomarkers for organ damage and/or dysfuntion are used in almost all areas of medicine. The brain has eluded this technological development for some time. Recently, the S100B protein has been shown to be a promising marker of brain damage. However, before S100S can reach clinical reality, several problems must be solved. The specificity of S100B requires special investigative attention. Although t

En källare ska alltid utformas så att den ger ett säkert och beständigt skydd mot fukt. Även om man inte avser att källaren ska vara uppvärmd kan det vara lämpligt att utforma fuktskyddet så att detta är möjligt i framtiden. I denna skrift beskrivs olika fuktbelastningar och fuktproblem i källare. Åtgärder för att åstadkomma en torr och fuktsäker källare redovisas samt lämpliga sätt att tilläggsis

Finite gradient pulse lengths are traditionally considered a nuisance in q-space diffusion NMR and MRI, since the simple Fourier relation between the acquired signal and the displacement probability is invalidated. Increasing the value of the pulse length leads to an apparently smaller value of the estimated compartment size. We propose that q-space data at different gradient pulse lengths, but wi

Abstract. Söderberg S, Ahrén B, Eliasson M, DinesenB, Olsson T (Umeå University, Umeå, Lund University and Luleå Hospital, Lund, Sweden; and Steno Diabetes Center, Gentofte, Denmark). The association between leptin and proinsulin is lost with central obesity. J Intern Med 2002; 252: 140-148. OBJECTIVE: Hyperproinsulinaemia and hyperleptinaemia are interrelated features of the insulin resistance sy

Essä om Terrence Malicks karriär och särpräglade berättarteknik.

Popular Abstract in Swedish Målsättningen med detta avhandlingsarbete har varit att undersöka cyklin D1 och HIF-1 i förhållande till ÖR i brösttumörer. Ytterligare en målsättning var att undersöka om cyklin D1 och HIF-1 kan påverka utfallet av tamoxifenbehandling i kliniska bröstcancerstudier. I delarbete 1 fann vi att i ÖR-positiva tumörer med områden där tumörcellerna faktiskt var ÖR-negativa, Estrogen receptor (ER) status can define breast cancer patients who would benefit from adjuvant tamoxifen therapy. However, resistance to tamoxifen is often observed and possible mechanisms may be loss or reduction of ER, dysfunctional ER- signaling and ligand independent activation of the receptor. Hypoxia and hypoxia inducible factor-1? (HIF-1) expression has been correlated to loss of ER in bre

This report presents theories and measurements of the mechanisms af heat transfer in fibrous materials (e.g. insulation of mineral wool type), and measurements of these mechanisms. The present work is part af a larger research program at the Division of Building Technology, Lund Institute of Technology, for investigating the behaviour of fibrous material as thermal insulation. A preliminary versio

We report on the applications of a single-longitudinal-mode (SLM) pulsed alexandrite laser system for diagnostics of parameters of flow/combustion interest. The laser system is characterized by its narrow linewidth, high peak power, and broad tunablity. The absolute frequency of the laser output was monitored by a wavelength diagnostic system, which included a high-resolution confocal etalon and a

Popular Abstract in Swedish Om modellbibliotek för termo-hydrauliska tillämpningar. Matematiska modeller och simulering är viktiga verktyg för att hantera tekniska system. Speciellt som trenden idag är att öka komplexiteten i system genom integrerad produktion och processoptimering. Att hantera dessa komplexa system kräver kunskaper inom många områden samtidigt. Modellbibliotek är ett bra sätt atMathematical modelling and simulation are important tools when dealing with engineering systems that today are becoming increasingly more complex. Tightly integrated production and process optimization are trends that give rise to heterogeneous systems, which are difficult to handle without expertise in several engineering disciplines. Model libraries provide an excellent way to package engineerin

OBJECTIVE: The aim of this study was to determine whether bone quality, as assessed by osteometry and histologic parameters, can be used to predict implant integration in conjunction with maxillary sinus reconstruction. STUDY DESIGN: Twelve patients with severely atrophied maxillary alveolar processes were treated through use of a two-stage surgical reconstructive strategy with implant placement 4

The β-delayed neutron branches from neutron-rich Be-isotopes have been measured with a setup sensitive down to thermal energies. For 14Be a new value of Pn = 101 ± 4% has been found for the total neutron-emission probability and an upper limit of 2.4% (95% confidence level) is imposed on the combination P2n + 3P3n of multi-neutron emission probabilities. Moreover, an improved value of Pn = 0.50 ±