Cross-presentation of cellular antigens is crucial for priming CD8(+) T cells, and generating immunity to intracellular pathogens-particularly viruses. It is unclear which intestinal phagocytes perform this function in vivo. To address this, we examined dendritic cells (DCs) from the intestinal lymph of IFABP-tOVA 232-4 mice, which express ovalbumin in small intestinal epithelial cells (IECs). Amo

Organizational discourse has emerged as a large research field and references to discourse are numerous. As with all dominating approaches problematizations of assumptions are important. This article, partly a follow up of the authors' frequently cited 2000 Human Relations article, provides a critical and perhaps provocative overview of some of the more recent work and tendencies within the field.

Miniaturized detection systems for nanometer-sized airborne particles are in demand, for example in applications for onboard diagnostics downstream particulate filters in modern diesel engines. A soot sensor based on resistivity measurements was developed and characterized. This involved generation of soot particles using a quenched co-flow diffusion flame; depositing the particles onto a sensor s

International water resources agreements for transboundary rivers in southern Africa are generally founded in system analysis models for water planning and allocation. The Water Resources Yield Model (WRYM) developed in South Africa has so far been the only model applied in official joint water resources studies aimed to form water-sharing agreements. The continuous discussion around the model per

In patients with acute type A aortic dissection (aTAAD), early post-surgical outcomes are largely influenced by preoperative conditions, specifically localized or generalized ischaemia. Such states are reflected in the recent Penn classification. Our aim was to determine the impact of preoperative ischaemia (by Penn class) on in-hospital and long-term mortality.

The signal crayfish Pacifastacus leniusculus is an invasive species in Sweden, threatening the red-listed nobel crayfish Astacus astacus through spreading the crayfish plague. Time-to-event models can handle censored data on such introduced populations for which the state (successful or not) is only partially known at the last observation, but even though data on introduced populations most often

This paper presents measurements of the polarization of W bosons in top quark decays, derived from t (t) over bar events with missing transverse momentum, one charged lepton and at least four jets, or two charged leptons and at least two jets. Data from pp collisions at a centre-of-mass energy of 7 TeV were collected with the ATLAS experiment at the LHC and correspond to an integrated luminosity o

Intermetallic compounds based on tantalum aluminides are of considerable interest in various industrial applications. In this work, the formation of tantalum aluminides has been studied in elemental powder mixtures containing 25, 50 and 66.7 at% Ta. A differential scanning calorimeter (DSC) was used to heat the samples up to 1500 K at 15 K min−1. Phase evolution was studied by heating a few sample

In the present study, source apportionment of the ambient summer and winter time particulate carbonaceous matter (PCM) in aerosol particles (PM1 and PM10) has been conducted for the Norwegian urban and rural background environment. Statistical treatment of data from thermal-optical, C-14 and organic tracer analysis using Latin Hypercube Sampling has allowed for quantitative estimates of seven diff

Protein E (PE) of Haemophilus influenzae is a highly conserved ubiquitous surface protein involved in adhesion to and activation of epithelial cells. The host proteins-vitronectin, laminin, and plasminogen are major targets for PE-dependent interactions with the host. To identify novel inhibitory molecules of PE, we used an in vitro selection method based on systematic evolution of ligands by expo

The competitive adsorption between phosphate and either one of seven benzenecarboxylates (benzoate, phthalate, trimellitate, trimesoate, hemimellitate, pyromellitate, and mellitate) on the surfaces of fine-particulate goethite (alpha-FeOOH) was investigated as a function of pH. The series of ligands contained Molecules with an increasing number of functional groups as well as three structural isom

Introduction: Our understanding of how comorbid diseases influence health-related quality of life (HRQL) in patients with chronic obstructive pulmonary disease (COPD) is limited and in need of improvement. The aim of this study was to examine the associations between comorbidities and HRQL as measured by the instruments EuroQol-5 dimension (EQ-5D) and the COPD Assessment Test (CAT). Methods: Infor

BACKGROUND: Young age at diagnosis and treatment with cranial radiation therapy are well studied risk factors for cognitive impairment in pediatric brain tumor survivors. Other risk factors are hydrocephalus, surgery complications, and treatment with intrathecal chemotherapy. Female gender vulnerability to cognitive sequelae after cancer treatment has been evident in some studies, but no earlier s

OBJECTIVES: In the present study, we investigated whether the cyclic adenosine monophosphate (cAMP)-activated protein kinase A (PKA) pathway may regulate the expression of AR and prostate-specific antigen (PSA) and whether there is a correlation between the expression of cAMP/PKA-associated genes and androgen receptors (ARs) in patients with prostate cancer (CaP). MATERIALS AND METHODS: The functi

The occupancy level of dwellings is an important parameter to know to determine the energy efficiency, energy use and indoor air quality, especially in low-energy buildings where the user-related energy uses, such as household electricity and domestic hot water heating, are significant parts of the energy balance in a building. For residential buildings, there is a lack of occupancy level data, wh

We present a comprehensive analysis of different techniques available for the spectroscopic analysis of FGK stars and provide a recommended methodology which efficiently estimates accurate stellar atmospheric parameters for large samples of stars. Our analysis includes a simultaneous equivalent width analysis of Fe I and Fe II spectral lines, and for the first time, utilizes on-the-fly non-local t

Activating the immune system has associated fitness costs, both immediate costs in the form of reduced current reproduction and long-term costs in the form of reduced life span and future reproduction. This indicates that immune system activation can be an important agent in life history trade-offs. In this review, we evaluate the importance of four currencies generally considered as potential med

The effect of eutrophication on particulate amorphous silica (ASi) sequestration was isolated and quantified in Lake St. Croix and Lake Pepin, two natural, human-impacted impoundments of the upper Mississippi River. In contrast to impoundments behind engineered dams, where silica (Si) fluxes may be changed by various aspects of dam construction, these two riverine lakes have long (9,000+ years) se