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Genetic networks with canalyzing Boolean rules are always stable

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are dynamically stable. Furthermore, for architectures with few inputs per node, the dynamics of the networks is close to critical. In addition, the fraction of gene

Antisense inhibition of laminin-8 expression reduces invasion of human gliomas in vitro

Using gene array technology, we recently observed for the first time an up-regulation of laminin alpha4 chain in human gliomas. The data were validated by semiquantitative reverse transcription-PCR for RNA expression and immunohistochemistry for protein expression. Moreover, increase of the alpha4 chain-containing laminin-8 correlated with poor prognosis for patients with brain gliomas. Therefore,

High-spin structure beyond band termination in Er-157

The angular-momentum induced transition from a deformed state of collective rotation to a noncollective configuration has been studied. In Er-157 this transition manifests itself as favored band termination near I=45 (h) over bar. The feeding of these band terminating states has been investigated for the first time using the Gammasphere spectrometer. Many weakly populated states lying at high exci

Scavenging of ultrafine particles by rainfall at a boreal site: observations and model estimations

Values of the scavenging coefficient determined from observations of ultrafine particles ( with diameters in the range 10 - 510 nm) during rain events at a boreal forest site in Southern Finland between 1996 and 2001 were reported by Laakso et al. (2003a). The estimated range of the median values of the scavenging coefficient was [ 7 x 10(-6)- 4 x 10(-5)] s(-1), which is generally higher than mode

The influence of hypoglycaemia on regional cerebral blood flow and cerebral volume in type 1 (insulin-dependent) diabetes mellitus

The effect of moderate hypoglycaemia (venous blood glucose 2.0 +/- 0.2 mmol/l; mean +/- SD) on regional cerebral blood flow and cerebral volume was studied in a group of ten right-handed patients with Type 1 (insulin-dependent) diabetes mellitus (age 26.0 +/- 2.4 years, duration 18.4 +/- 3.8 years) using an intravenous Xenon 133 single photon emission computed tomography technique. After 10 min of

Simple counting of nailfold capillary density in suspected systemic sclerosis - 9 years' experience.

Objectives: Capillary damage is a characteristic feature of systemic sclerosis (SSc). This work aimed to explore the potential clinical value of simple microscopic counting of capillary density. Methods: In 325 patients admitted because of a clinical suspicion of SSc and in 80 healthy controls, nailfold capillary microscopy (NCM) was performed using a stereo-zoom microscope in 20x magnification an

Philopatry of winter moult area in migratory great reed warblers Acrocephalus arundinaceus demonstrated by stable isotope profiles

Abstract in UndeterminedStable carbon- (delta(13)C), nitrogen- (delta(15)N) and hydrogen (delta D) isotope profiles in feathers of migratory Great Reed Warblers Acrocephalus arundinaceus recaptured for 2 or more years in 6 successive years were examined to test whether the isotope profiles of individual warblers appeared to be consistent between years. Similar isotopic signatures in successive yea

Tracking fish movements in the ocean

Until recent technical developments, such as the use of satellite telemetry, little has been known about the movements, physiology and behaviour of long-distance migratory fish. Recently, Bloch and co-workers used electronic data storage tags surgically implanted into bluefin tuna Thunnus thynnus or linked to satellites, to reveal interesting details of the movement patterns, area use and environm

The bacterial flora of vacuum-packed cold-smoked salmon stored at 7 degrees C, identified by direct 16S rRNA gene analysis and pure culture technique

Aims: The indigenous flora of freshly chilled cold-smoked salmon just after the vacuum packaging, and the spoilage flora after storage, in vacuum package at 7 degrees C for 19 days, were to be investigated with two different sampling strategies. Methods and Results: Identification was performed using 16S rRNA sequencing of both isolated bacteria and bacterial DNA from tissue extract. The indigenou

C-14 content in vegetation in the vicinities of Brazilian nuclear power reactors

Abstract in UndeterminedC-14 specific activities were measured in grass samples collected around Brazilian nuclear power reactors. The specific activity values varied between 227 and 299 Bq/kg C. Except for two samples which showed C-14 specific activities 22% above background values, half of the samples showed background specific activities, and the other half had a C-14 excess of 1-18%. The high

Compensation for longitudinal chromatic aberration in the eye of the firefly squid, Watasenia scintillans

The camera eyes of fishes and cephalopods have come forth by convergent evolution. In a variety of vertebrates capable of color vision, longitudinal chromatic aberration (LCA) of the optical system is corrected for by the exactly tuned longitudinal spherical aberration (LSA) of the crystalline lens. The LSA leads to multiple focal lengths, such that several wavelengths can be focused on the retina

Growth and reactivity of titanium oxide ultrathin films on Ni(110)

Soft X-ray photoelectron spectroscopy (SXPS) and X-ray absorption near-edge structure (XANES) have been combined with low-energy electron diffraction (LEED) to examine the growth of titanium dioxide thin films on Ni(110). Depending on the initial titanium coverage, the formation of two different films is observed, a quasi-hexagonal phase and a film with rutile (110) rods. Spectroscopy (SXPS and XA

Symbolic technologies: Machines and the Marxian notion of fetishism

By extending the Marxian theory of fetishism from money and commodities to machines, we may achieve an epistemological shift in our understanding of the foundations of 'technological development'. The first part of the article discusses previous definitions of fetishism in order to distil some central themes that appear to be particularly significant to the argument on machine fetishism. It is arg