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An investigation of the thermo-hydraulic performance of the smooth wavy fin-and-elliptical tube heat exchangers utilizing new type vortex generators

A three-dimensional CFD numerical simulation is successfully carried out on thermo-hydraulic characteristics of a new smooth wavy fin-and-elliptical tube (SWFET) heat exchanger with three new types of vortex generators (VGs), namely - rectangular trapezoidal winglet (RTW), angle rectangular winglet (ARW) and curved angle rectangular winglet (CARW). Several parameters have been examined in this stu

The androgen receptor and stem cell pathways in prostate and bladder cancers (Review)

Bladder cancer is three times more common in men than in women. However, the physiological basis of the male predominance of bladder cancer remains poorly understood. A higher than expected association of prostate and bladder cancers has also been reported which may indicate a common mechanism of carcinogenesis. Consistent with this, androgens and the androgen receptor (AR) play essential roles in

Death causes in breast cancer patients

Background: Due to improved outcomes in breast cancer (BCa), the proportion of affected women dying of other causes has increased. Thus, a better survival of BCa requires knowledge of other causes of death. Materials and methods: Data on the population, cancers, and causes of death were gathered from the nationwide Swedish Family-Cancer Database, enrolling similar to 3.68 million Swedish women. A

Experimental Studies of Advanced Ignition Systems for Lean Burn Natural Gas Engines

One of the greatest challenges for the transport sector today is reducing its environmental impact. This applies especially to the emission aspects, much due to increasingly stringent emissions legislations. Carbon dioxide (CO2) is considered an important greenhouse gas, but also unburned hydrocarbons (HC), nitric oxides (NOx) and soot pose environmental as well as health risks. Compared to diesel

Genetic and epigenetic influence on oxidative phosphorylation, islet function and type 2 diabetes in humans

Popular Abstract in Swedish Diabetes är en grupp av sjukdomar som kännetecknas av förhöjda halter av glukos (socker) i blodet. Förekomsten av diabetes ökar i snabb takt i hela världen. År 2011 var 366 miljoner människor drabbade av diabetes, och denna siffra beräknas till 522 miljoner år 2030 om ingen avgörande åtgärd genomförs. Typ 2 diabetes är den vanligaste formen av diabetes och utgör ungefärThe prevalence of type 2 diabetes (T2D) is increasing worldwide. T2D is a heterogeneous disease caused by a complex interplay between multiple genetic, epigenetic and non-genetic factors. The disease is characterised by impaired insulin secretion from pancreatic β-cells and insulin resistance in peripheral tissues. Mitochondrial ATP production by oxidative phosphorylation (OXPHOS) is known to play

IgG Glycan Hydrolysis Attenuates ANCA-Mediated Glomerulonephritis

Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (Pr3) are considered pathogenic in ANCA-associated necrotizing and crescentic glomerulonephritis (NCGN) and vasculitis. Modulation of ANCA IgG glycosylation may potentially reduce its pathogenicity by abolishing Fc receptor mediated activation of leukocytes and complement Here, we investigated

The prevalence of anemia and iron deficiency in IBD outpatients in Scandinavia

Objective. To evaluate the prevalence of anemia and iron deficiency (ID) among patients with inflammatory bowel disease (IBD) in the Scandinavian countries. Material and methods. A cross-sectional study including 429 IBD patients from six centers in Denmark, Norway and Sweden. Patients were screened for anemia and ID. Each center included similar to 5% of their IBD cohort. Patients were consecutiv

Care planning at home: a way to increase the influence of older people?

Abstract in UndeterminedIntroduction: Care-planning meetings represent a common method of needs assessment and decision-making practices in elderly care. Older people's influence is an important and required aspect of these practices. This study's objective was to describe and analyse older people's influence on care-planning meetings at home and in hospital. Methods: Ten care-planning meetings we

On the Infinite Horizon Performance of Receding Horizon Controllers

Receding horizon control is a well established approach for control of systems with constraints and nonlinearities. Optimization over an infinite time-horizon, which is often computationally intractable, is therein replaced by a sequence of finite horizon problems. This paper provides a method to quantify the performance degradation that comes with this approximation. Results are provided for prob

Influence of genetically modified organisms on agro-ecosystem processes

Biotechnology offers extensive possibilities to incorporate new traits into organisms. Genetically modified (GM) traits relevant for agro-ecosystems include traits such as pest resistance and herbicide tolerance in crop plants, increased growth rate in fish and livestock, and enhanced nitrogen-fixation capabilities of soil microbes. In this review, we evaluated the direct and indirect trait-specif

Comparison of in vitro methods of measuring mucoadhesion: Ellipsometry, tensile strength and rheological measurements.

In this work three in vitro methods for the measurement of mucoadhesion have been compared: ellipsometry, tensile strength and rheology. The conditions used for the three methods have been as similar as possible. Six different polymers were investigated: sodium carboxymethyl cellulose (CMC), hydroxyethyl cellulose (HEC), chitosan, polyvinyl pyrrolidone (PVP) and two cross-linked polyacrylic acids,

Ecologically unequal exchange and landesque capital on Kinmen Island

Two conceptual tools in historical analyses of environmental issues and political ecologies have gained much attention in recent years: ecologically unequal exchange and landesque capital. The former narrows in on how societal relations of power allow for the physical transfer of environmental degradation—upon which our daily consumption rests—to places far away from our environmentally clean (and

Determination of Clothing Evaporative Resistance on a Sweating Thermal Manikin in an Isothermal Condition: Heat Loss Method or Mass Loss Method?

This paper addresses selection between two calculation options, i.e heat loss option and mass loss option, for thermal manikin measurements on clothing evaporative resistance conducted in an isothermal condition (Tmanikin = Ta = Tr). Five vocational clothing ensembles with a thermal insulation range of 1.05–2.58 clo were selected and measured on a sweating thermal manikin ‘Tore’. The reasons why t

A Response to Honig and Samuelsson (2014)

Honig and Samuelsson (2014) recently published an article in this outlet criticizing “Does business planning facilitate the development of new ventures? “ a paper I wrote with Scott Shane nearly 15 years ago. They claim that their effort adds to the discussion of (a) the merits of business planning, (b) data replication and extension, (c) sample selection bias, (d) evaluation of normative research