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We're number two! Beta cities and the cultural economy

Given that not every city can be an alpha city in today's global urban hierarchy, what options do beta cities such as Toronto or Chicago realistically have in the cultural economy? Put differently, if cultural capitals such as New York, London, Paris, and Tokyo play critically important roles in certifying and establishing new trends in theatre, fashion, and other cultural industries, how can beta

Realizing Lateral Wrap-Gated Nanowire FETs: Controlling Gate Length with Chemistry Rather than Lithography.

An important consideration in miniaturizing transistors is maximizing the coupling between the gate and the semiconductor channel. A nanowire with a coaxial metal gate provides optimal gate-channel coupling but has only been realized for vertically oriented nanowire transistors. We report a method for producing laterally oriented wrap-gated nanowire field-effect transistors that provides exquisite

Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors.

Hereditary retinal degeneration (RD) relates to a heterogeneous group of blinding human diseases in which the light sensitive neurons of the retina, the photoreceptors, die. RD is currently untreatable and the underlying cellular mechanisms remain poorly understood. However, the activity of the enzyme poly-ADP-ribose polymerase-1 (PARP1) and excessive generation of poly-ADP-ribose (PAR) polymers i

Fitch's paradox and ceteris paribus modalities

The paper attempts to give a solution to the Fitch's paradox though the strategy of the reformulation of the paradox in temporal logic, and a notion of knowledge which is a kind of ceteris paribus modality. An analogous solution has been offered in a different context to solve the problem of metaphysical determinism.

Field-driven geometrical phases in a time-periodic quantum system

We apply Floquet theory to explore the geometry of the Hilbert space under the influence of a time-periodic field. The geometrical phase is found to be induced by field-driven hybridizations when the photon energy of the driving field is close to the transition energies of the states of a quantum system. The phases of two hybridized states are phase locked to each other. We show that the geometric

EndoE from Enterococcus faecalis Hydrolyzes the Glycans of the Biofilm Inhibiting Protein Lactoferrin and Mediates Growth.

Glycosidases are widespread among bacteria. The opportunistic human pathogen Enterococcus faecalis encodes several putative glycosidases but little is known about their functions. The identified endo-β-N-acetylglucosaminidase EndoE has activity on the N-linked glycans of the human immunoglobulin G (IgG). In this report we identified the human glycoprotein lactoferrin (hLF) as a new substrate for E

Communication experience of individuals treated with home mechanical ventilation.

Background: Mechanical ventilatory support seriously affects speaking and communication, and earlier studies show that many ventilator-supported patients experience difficulties and frustration with their speech and voice production. Since there is a growing number of individuals who require mechanical ventilatory support and there is a paucity of studies that examine ventilator-supported communic

Direct numerical simulation of lean premixed CH4/air and H-2/air flames at high Karlovitz numbers

Three-dimensional direct numerical simulation with detailed chemical kinetics of lean premixed CH4/air and H-2/air flames at high Karlovitz numbers (Ka similar to 1800) is carried out. It is found that the high intensity turbulence along with differential diffusion result in a much more rapid transport of H radicals from the reaction zone to the low temperature unburned mixtures (similar to 500 K)

A first comparison of the responses of a He-4-based fast-neutron detector and a NE-213 liquid-scintillator reference detector

A first comparison has been made between the pulse-shape discrimination characteristics of a novel He-4-based pressurized scintillation detector and a NE-213 liquicl-scintillator reference detector using an Am/Be mixed-field neutron and gamma-ray source and a high-resolution scintillation-pulse digitizer. In particular, the capabilities of the two fast neutron detectors to discriminate between neu

Simple and efficient decoupling of compact arrays with parasitic scatterers

Compact arrays such as multiple antennas on a mobile terminal suffer from low efficiency and high correlation between antenna signals. In the present paper, a simple and rigorous procedure for decoupling two closely coupled antennas with a parasitic scatterer is proposed. The parasitic scatterer, which can be an additional antenna, acts as a shield between two active antenna elements. In contrast

Caries risk assessment in young adults using Public Dental Service guidelines and the Cariogram-a comparative study

Objectives. To investigate the caries risk profiles in young adults and to compare the risk classification using the Public Dental Service (PDS) guidelines with a risk assessment program, the Cariogram. Materials and methods. All 19-year-old patients registered at eight public dental clinics were invited to participate (n = 1699). The study group who completed the baseline examination consisted of

Labour Market activationn Policies for the Long-Term Ill - A Sick Idea?

Abstract in UndeterminedThis paper addresses the failure of activation programmes to achieve a rapid return to work when they are directed towards the long-term ill. The empirical basis for the paper is an analysis of the outcomes for 691 individuals in Sweden chosen for a re-activation policy programme to shorten their sick leave and increase their chances of returning to work. The outcome at the

Fixed parameter algorithms for the minimum weight triangulation problem

We discuss and compare four fixed parameter algorithms for finding the minimum weight triangulation of a simple polygon with (n - k) vertices on the perimeter and k vertices in the interior (hole vertices), that is, for a total of n vertices. All four algorithms rely on the same abstract divide-and-conquer scheme, which is made efficient by a variant of dynamic programming. They are essentially ba

Mass screening for celiac disease from the perspective of newly diagnosed adolescents and their parents: A mixed-method study

Background: Mass screening for celiac disease (CD) as a public health intervention is controversial. Prior to implementation, acceptability to the targeted population should be addressed. We aimed at exploring adolescents' and parents' experiences of having the adolescents' CD detected through mass screening, and their attitudes towards possible future mass screening. Methods: All adolescents (n =

Luminance-dependence of spatial vision in budgerigars (Melopsittacus undulatus) and Bourke's parrots (Neopsephotus bourkii).

Budgerigars (Melopsittacus undulatus) and Bourke's parrots (Neopsephotus bourkii) are closely related birds with different activity patterns. Budgerigars are strictly diurnal while Bourke's parrots are active in dim twilight. Earlier studies show that the intensity threshold of colour vision is similar in both species while Bourke's parrots have larger eyes with a higher density of rods than budge

A new small-angle X-ray scattering set-up on the crystallography beamline I711 at MAX-lab.

A small-angle X-ray scattering (SAXS) set-up has recently been developed at beamline I711 at the MAX II storage ring in Lund (Sweden). An overview of the required modifications is presented here together with a number of application examples. The accessible q range in a SAXS experiment is 0.009-0.3 A(-1) for the standard set-up but depends on the sample-to-detector distance, detector offset, beams