A MOUSE MODEL FOR RIEGER SYNDROME.
Rieger syndrome is an autosomal dominant human disorder affecting eye, tooth and umbilical development, andwhose primary morbidity is the 50% occurrence of glaucoma in affected individuals. The identification of etiologicmutations in the PITX2 gene and its encoded protein, solurshin, inspired the development of a transgenic animal thatmight serve as a model for this disorder. In addition, the more