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Tissue transglutaminase (tTg) has been identified as the major autoantigen in coeliac disease (CD). ELISA methods have been developed for measuring the autoantibody. There are divergent reports on the effects of calcium on the antibody binding to tTg. Furthermore, zinc is a potent inhibitor of tTg. To better understand the role of transglutaminase in CD, we have studied the stability of commercial
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Two lesions, actinic keratosis (AK) and squamous cell carcinoma in situ (CIS), are believed to be precursors of squamous cell carcinoma (SCC) of the skin. These lesions can serve as an excellent model system for studying genetic changes associated with the inception of skin SCC. In the present study, five such lesions of the skin, three AKs and two AK+CIS, from three patients were short-term cultu
Thylakoids isolated from tobacco were fragmented by sonication and the vesicles so obtained were separated by partitioning in aqueous polymer two-phase systems. By this procedure, grana vesicles were separated from stroma exposed membrane vesicles. The latter vesicles could be further fractionated by countercurrent distribution, with dextran-polyethylene glycol phase systems, and divided into two
Popular Abstract in Swedish Denna islamologiska avhandling diskuterar och analyserar den islamtolkning som gjorts av den muslimske tänkaren Nurcholish Madjid i Indonesien. Nurcholish ¬ som nyligen dog vid sextisex års ålder - har bidragit till reformeringen av islamiskt tänkande i Indonesien i över trettio år. Hans idéer är starkt påverkade av den lokala indonesiska kontexten, men utgör också en dThis dissertation in the field of Islamic studies offers a critical analysis of Nurcholish Madjid's attempt to interpret Islam within the framework of modern Indonesia. Nurcholish, who recently passed away at the age of sixty-six, had been active in the reform of Islamic thought for over thirty years, and while remaining deeply coloured by the local Indonesian context, was also part of a global an
Utgångspunkten för projektet Skåne i god form II har varit de problem på arbetsmarknaden som kan relateras till arbetsmiljön och som resulterar i hög sjukfrånvaro och svårigheter att behålla och nyrekrytera arbetskraft. Projektet har syftat till att skapa möjligheter för de anställda att tillsammans med designer granska sin egen arbetsmiljö och de arbetsuppgifter man har och utarbeta förslag på hu
If individuals occupy habitats in a way that maximizes their fitness, if they are free to occupy the habitats they choose and if fitness declines with population density, then their abundance across habitats should follow an ideal free distribution. But, if individuals are genetically related, this simple fitness-maximization mechanism breaks down. Habitat occupation should obey Hamiltons rule (na
Observations of the ultra-sharp-lined HgMn star chi Lupi made with the Goddard High Resolution Spectrograph after the Hubble Space Telescope First Servicing Mission display the effect of COSTAR corrective optics upon the spectral resolution of several observing modes. The resolution is restored to levels expected in the absence of the telescope spherical aberration for all observations made throug
In a large variety of disciplines, fundamental studies often straddle in self-referential situations, in need of relativization to language and complementaristic resolution. In such attempts, the languages at play are hardly visible themselves. Only shadows of language, somewhat characteristic of the various disciplines, become visible and tractable. We select two domains, quantum mechanics and cy
Intramuscular triacylglycerol is an important energy store and is also related to insulin resistance. The mobilization of fatty acids from this pool is probably regulated by hormone-sensitive lipase (HSL), which has recently been shown to exist in muscle and to be activated by both adrenaline and contractions. Adrenaline acts via cAMP-dependent protein kinase (PKA). The signalling mediating the ef
PURPOSE: To determine the normal values of the anterior and posterior capsular distances of the hip joint in healthy children by means of US, using MR imaging as reference, and to evaluate any possible correlation between age, length, weight and anterior capsular distance (ACD). MATERIAL AND METHODS: In our first study both hips in 14 healthy children (5-18 years old) were examined with US and MR
Here we present evidence that a fibroblast heparan sulphate proteoglycan of approx. 300 kDa and with a core protein of apparent molecular mass 70 kDa is covalently linked to the plasma membrane via a linkage structure involving phosphatidylinositol. Phosphatidylinositol-specific phospholipase C releases such a heparan sulphate proteoglycan only from cells labelled with [35S]sulphate in the absence
Three strains capable of mineralizing nonylphenol as sole carbon source were isolated from a sample of contaminated soil and characterized as two Pseudomonas spp. and a Stenotrophomonas sp. The two Pseudomonas spp. expressed characteristics typical of psychrophiles growing optimally of 10 °C and capable of growing at 0 °C. The Stenotrophomonas sp. was more likely psychrotrophic because it had an o
A new approach to the low cycle fatigue problem, based on non-linear fracture mechanics, is investigated. The method is designed to predict final failure of engineering structures containing cracks that are small compared to the significant length dimensions of the structure. The suggested procedure is simple to apply and the failure load can be predicted for a moderately low number of major load
Background: As part of a larger study whose objective is to develop an abbreviated version of the EORTC QLQ-C30 suitable for research in palliative care, analyses were conducted to determine the feasibility of generating a shorter version of the 4-item emotional functioning (EF) scale that could be scored in the original metric. Methods: We used data from 24 European cancer studies conducted in 10
