Tapasin (tpn), an essential component of the MHC class I (MHC I) loading complex, has a canonical double lysine motif acting as a retrieval signal, which mediates retrograde transport of escaped endoplasmic reticulum (ER) proteins from the Golgi back to the ER. In this study, we mutated tpn with a substitution of the double lysine motif to double alanine (GFP-tpn-aa). This mutation abolished inter

The novel "Reflexer" (Reflections) is the first novel in Swedish literature with a transgender person as the main character. "Reflexer" is a coming-out-novel before the genre was invented and deals with both sexual and gender identities in the early 20th century Sweden. "Reflexer" can thematically be linked to our contemporary LGBTQ literature.

This chapter describes and analyzes the public relations strategies and practices of a public organization, a local rescue services, in the process of establishing credibility and building trust in multicultural areas. The trust-building efforts are a response to several years of social unrest, communicative clashes and hostile treatment between operative firemen and residents in certain areas. Th

The focus of attention in this article is that of milieux as forges for creativity and renewal. Among the milieux presented are places, corporations and research institutions. The renewal discussed here includes art, architecture, music and literature as well as science and technology. The goal of this article is to identify characteristics of importance in environments where exceptionally creativ

The spectral efficiency of a volume in a MIMO environment is analyzed. The analysis is based on a spherical mode expansion for the propagation, the radiation Q for the antennas, and Fano theory for the broadband matching

This paper investigates the mean square error optimal time-frequency kernel for estimation of the Wigner-Ville spectrum of a certain class of nonstationary processes. The class of locally stationary processes have a simplified covariance structure which facilitates analysis. We give a formula for the optimal kernel in the ambiguity domain and conditions that are sufficient for the optimal time-fre

Values and opinions about what is valuable, are of centralimportance in risk and vulnerability analyses. Yet what is considered valuableis seldom explicitly established. The aim of this study is to explore what groupsof civil servants express as valuable and worth protecting when performing riskand vulnerability analyses in their organisations and to discuss the underlyingreasons for their stipula

Popular Abstract in Swedish Avhandlingen handlar om den aspekt av människans självbild, eller självet, som på engelska kallas possible selves, och som på svenska skulle kunna kallas "möjliga själv" (en etablerad svensk översättning saknas). Detta är framtidsföreställningar eller framtidsbilder där vi ser oss själva i framtida situationer eller tillstånd, och teorin om möjliga själv presenterades fPossible selves are conceptions or images of ourselves in future states or situations. The theory about possible selves used in the present thesis was developed in a social cognitive tradition of research on the self, where the self is seen as a knowledge structure (Markus & Nurius, 1986). Possible selves are parts of this knowledge structure and possible selves are of importance for motivatio

In this paper, we derive an Expectation-Maximization algorithm for hidden Markov models (HMMs) with a multivariate Rayleigh mixture model (RMM) in each state. We compare the use of multivariate RMMs to multivariate Gaussian mixture models in the general case where the HMM is a dynamic model and for the special case where it has a single state and reduces to a static model. We evaluate the proposed

To be able to guarantee service quality end-to-end Quality of Service has to be deployed. This thesis addresses the problems with applying QoS end-to-end over today’s Internet. A rather pessimistic conclusion states that QoS over Internet is hard (impossible?) to realize without introducing virtual circuits or similar. The concept of flows and label switching is introduced. Some QoS techniques are