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Late Holocene peat paleodust deposition in south-western Sweden - exploring geochemical properties, local mineral sources and regional aeolian activity

Atmospheric mineral dust not only interacts with the climate system by scattering incoming solar radiation and affecting atmospheric photochemistry, but also contributes critical nutrients to marine and terrestrial ecosystems. In a high-resolution analysis of paleodust deposition, peat development and soil dust sources, we assess the interplay between dust deposition and bog development of the Dav

Statins Induce Locomotion and Muscular Phenotypes in Drosophila melanogaster That Are Reminiscent of Human Myopathy : Evidence for the Role of the Chloride Channel Inhibition in the Muscular Phenotypes

The underlying mechanisms for statin-induced myopathy (SIM) are still equivocal. In this study, we employ Drosophila melanogaster to dissect possible underlying mechanisms for SIM. We observe that chronic fluvastatin treatment causes reduced general locomotion activity and climbing ability. In addition, transmission microscopy of dissected skeletal muscles of fluvastatin-treated flies reveals stro

Mental health, sleep and pain in elite Para athletes and the association with injury and illness ‐ a prospective study

IntroductionThe interest in Para athletes’ health continues to increase. Still, there are few studies that have evaluated health parameters beyond injury and illness in this athlete population.ObjectiveTo assess: i) the weekly proportion of elite Para athletes reporting anxiety/depression, low sleep levels (≤7 hours) and pain over 52 weeks and; ii) and to explore whether these health parameters ar

Clusters of risk factors in metabolic syndrome and their influence on central blood pressure in a global study

The effect of metabolic syndrome (MetS) and clusters of its components on central blood pressure (CBP) has not been well characterized. We aimed to describe the effect of MetS and clusters of its components on CBP in a large population and to identify whether this effect differs in men and women. We studied 15,609 volunteers (43% women) from 10 cohorts worldwide who participated in the Metabolic s

Soft X-ray signatures of cationic manganese-oxo systems, including a high-spin manganese(v) complex

Manganese-oxo species catalyze key reactions, including C-H bond activation or dioxygen formation in natural photosynthesis. To better understand relevant reaction intermediates, we characterize electronic states and geometric structures of [MnOn]+ manganese-oxo complexes that represent a wide range of manganese oxidation states. To this end, we apply soft X-ray spectroscopy in a cryogenic ion tra

Analogy as a search procedure : a dimensional view

In this paper, we outline a comprehensive approach to composed analogies based on the theory of conceptual spaces. Our algorithmic model understands analogy as a search procedure and builds upon the idea that analogical similarity depends on a conceptual phenomena called ‘dimensional salience.’ We distinguish between category-based, property-based, event-based, and part-whole analogies, and p

Multiple Environmental Influences on the Lightning of Cold-Based Continental Convection. Part II : Sensitivity Tests for Its Charge Structure and Land-Ocean Contrast

In Part I, an electrification scheme was described and a simulation of an observed cold-based storm from the U.S. Great Plains was validated with electrical observations. Most charge in the storm was separated by rebounding collisions of secondary ice originating from prior graupel-snow collisions. In this Part II, sensitivity tests are performed with the control simulation (Part I) and influences

CAFS : Cost-Aware Features Selection Method for Multimodal Stress Monitoring on Wearable Devices

Objective: Today, stress monitoring on wearable devices is challenged by the tension between high-detection accuracy and battery lifetime driven by multimodal data acquisition and processing. Limited research has addressed the classification cost on multimodal wearable sensors, particularly when the features are cost-dependent. Thus, we design a Cost-Aware Feature Selection (CAFS) methodology that

Long-term incidence of endometrial cancer after endometrial resection and ablation : A population based Swedish gynecologic cancer group (SweGCG) study

Introduction: Minimally invasive methods to reduce menorrhagia were introduced in the 1980s and 1990s. Transcervical endometrial resection (TCRE) and endometrial ablation (EA) are two of the most frequently used methods. As none of them can guarantee a complete removal of the endometrium, there are concerns that the remaining endometrium may develop to endometrial cancer (EC) later in life. The pr

The Leydig cell biomarker INSL3 as a predictor of age-related morbidity : Findings from the EMAS cohort

Background: Insulin-like peptide 3 (INSL3) is a constitutive hormone secreted in men by the mature Leydig cells of the testes. It is an accurate biomarker for Leydig cell functional capacity, reflecting their total cell number and differentiation status. Objectives: To determine the ability of INSL3 to predict hypogonadism and age-related morbidity using the EMAS cohort of older community-dwelling

Att möta människors oro och rädsla för björn och varg : Praktiska råd och vetenskapligt kunskapsunderlag

Människors oro och rädsla för stora rovdjur har under de senaste tio åren studerats inom tvärvetenskapliga samarbeten mellan miljöpsykologi, emotionspsykologi och viltekologi. Forskningen har fokuserat på att förstå underliggande orsaker till människors oro och rädsla samt att utveckla och utvärdera olika förvaltningsåtgärder för situationer då människor uttrycker rädsla för stora rovdjur.Naturvår

Surgically Treated Neuroma in Upper Extremity : Patient Characteristics and Factors Influencing Outcome of Surgery

Background: Neuroma formation occurs after inappropriately or untreated nerve injuries. Patients surgically treated for neuroma were characterized and factors influencing outcome evaluated. Methods: In a retrospective observational study, data from medical records of patients surgically treated for neuroma in two Swedish regions were analyzed. Results: In 115 included patients (median age at surge

Central nervous system monoaminergic activity in hip osteoarthritis patients with disabling pain : associations with pain severity and central sensitization

Introduction: Monoaminergic activity modulates nociceptive transmission in the central nervous system (CNS). Although pain is the most disabling symptom of osteoarthritis (OA), limited knowledge exists regarding the CNS mechanisms that amplify pain and drive sensitization processes in humans.Objectives:The main objective of this study was to evaluate associations between cerebrospinal fluid (CSF)

Primary prophylaxis in children with severe haemophilia A and B-Implementation over the last 20 years as illustrated in real-world data in the PedNet cohorts

INTRODUCTION: The prophylactic regimen in children with severe haemophilia is suggested in various publications and guidelines. Few data exist on its implementation in clinical practice.AIM: To investigate the implementation of primary prophylaxis based on real-life data from PedNet during the last 20 years.METHODS: All children from the PedNet cohort (n = 1260) with severe haemophilia A (SHA) or

The time course of metabolic plasticity and its consequences for growth performance under variable food supply in the northern pike

Many species up- or downregulate their resting metabolic rate (RMR) when they encounter favourable or unfavourable feeding conditions, respectively. This is thought to promote faster growth when food is abundant and conserve energy reserves when food is scarce. The time it takes to express metabolic plasticity remain little studied. Here, we develop a conceptual model showing how rapid or slow met

Tool use and tooling in ravens (Corvus corax) : A review and novel observations

Corvids are known for their cognitive flexibility, and many have innovated various forms of tool use. Here, we review tool use and tooling in common ravens (Corvus corax) and describe additional observations. In total, they have used tools in 10 submodes and 11 modes. Of these modes, four were observed in captivity only, four in the wild only and three in both contexts. Five of these modes constit

Cultural evolution leads to vocal iconicity in an experimental iterated learning task

Experimental and cross-linguistic studies have shown that vocal iconicity is prevalent in words that carry meanings related to size and shape. Although these studies demonstrate the importance of vocal iconicity and reveal the cognitive biases underpinning it, there is less work demonstrating how these biases lead to the evolution of a sound symbolic lexicon in the first place. In this study, we s

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In this chapter we summarize the solution developed by team KTH for the Amazon Picking Challenge 2016 in Leipzig, Germany. The competition, which simulated a warehouse automation scenario, was divided into two parts: a picking task, where the robot picks items from a shelf and places them into a tote, and a stowing task, where the robot picks items from a tote and places them in a shelf. We descri