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Post-termination complex disassembly by ribosome recycling factor, a functional tRNA mimic

Ribosome recycling factor (RRF) together with elongation factor G (EF-G) disassembles the post- termination ribosomal complex. Inhibitors of translocation, thiostrepton, viomycin and aminoglycosides, inhibited the release of tRNA and mRNA from the post-termination complex. In contrast, fusidic acid and a GTP analog that fix EF-G to the ribosome, allowing one round of tRNA translocation, inhibited

Neuronal plasticity and dendritic spines: effect of environmental enrichment on intact and postischemic rat brain.

The authors compared the influence of environmental enrichment on intact and lesioned brain, and tested the hypothesis that postischemic exposure to an enriched environment can alter dendritic spine density in pyramidal neurons contralateral to a cortical infarct. The middle cerebral artery was occluded distal to the striatal branches in spontaneously hypertensive rats postoperatively housed eithe

The impact of stent design on proximal stent-graft fixation in the abdominal aorta: an experimental study

OBJECTIVE: to study the proximal fixation of different aortic stent grafts in comparison to a hand-sewn anastomosis. DESIGN: experimental study. MATERIAL: the infrarenal aorta of 16 human cadavers were exposed, left in situ and transected 3 cm above the aortic bifurcation to mimic an infrarenal aortic neck. Stent grafts were deployed through a sheath 5 cm into the aorta. Ancure, Talent, Vanguard,

Impact of natural and artificial UVB radiation on motility and growth rate of marine dinoflagellates

The growth rates and motility of dinoflagellates were studied in the field in the presence or absence of UVB radiation, as well as in the laboratory under artificial radiation conditions. Photosynthetically active radiation (PAR, 400–700 nm) and UVB radiation showed large variations due to cloud cover and seasonal changes in natural daylight. In Swedish coastal water, UVB radiation was attenuated

Energy transfer within Zn-porphyrin dendrimers: Study of the singlet-singlet annihilation kinetics

In this article, we explore energy transfer processes within a series of Zn-porphyrin-appended dendrimers by means of excitation intensity dependent transient absorption measurements. We report singlet-singlet annihilation on two distinct time scales of 18 +/- 5 ps and 130 +/- 10 ps in the dimer and the dendrimers. The two distinct processes reflect the presence of two structural conformer distrib

Effectiveness of caching in a distributed digital library system

Today independent publishers are offering digital libraries with fulltext archives. In an attempt to provide a single user-interface to a large set of archives, the studied Article-Database-Service offers a consolidated interface to a geographically distributed set of archives. While this approach offers a tremendous functional advantage to a user, the fulltext download delays caused by the networ

Biological growth on mineral façades

During the last years there has been reported considerable and rapid contamination on newly built rendered façades in Sweden due to biological growth. The problem is believed to occur mostly on façades of render applied on thermal insulation, but apart from this it is difficult to find clear relationships indication which façades might be infected. The aim of this project is to explain why certain

DT-kolografi i stället för koloskopi. Ny datortomografisk metod vid misstänkt kolonpolyp eller malign tumör

Datortomografi av kolon (DT-kolografi) är en ny tillämpning av datortomografi, som gör det möjligt att med hög diagnostisk säkerhet upptäcka tumörer och polyper större än 10 mm. Metoden medför mindre obehag och smärta än koloskopi och kolonröntgen. Behovet av tarmrengöring är dock detsamma. DT-kolografi kan, som initial undersökning vid misstanke om maligna förändringar eller kolonpolyper, komma a

Determination of A(FB)(b) at the Z pole using inclusive charge reconstruction and lifetime tagging

A novel high precision method measures the b-quark forward-backward asymmetry at the Z pole on a sample of 3,560,890 hadronic events collected with the DELPHI detector in 1992 to 2000. An enhanced impact parameter tag provides a high purity b sample. For event hemispheres with a reconstructed secondary vertex the charge of the corresponding quark or anti-quark is determined using a neural network

Evidence of a defined spatial arrangement of hyaluronate in the central filament of cartilage proteoglycan aggregates

Aggregates of proteoglycans from the Swarm rat chondrosarcoma reassembled in vitro have been studied by rotary-shadowing electron microscopy, and shown to be similar to native structures that have never been dissociated [Morgelin, Engel, Heinegard and Paulsson (1992) J. Biol. Chem. 267, 14275-14284]. A hyaluronate with defined chain length (HAshort) has now been prepared by autoclaving high-Mr hya

Ross operation for bicuspid aortic valve disease in adults: is it a valid surgical option?

OBJECTIVE: The validity of the Ross operation as freestanding root replacement in adult patients with bicuspid aortic valve disease has lately been questioned. We have analyzed retrospectively our results in 23 adult patients (19 males) operated for bicuspid aortic valve disease ad modum "Ross" employing a freestanding root replacement technique. DESIGN: In 9 patients the dominant aortic valve les

Tooth loss and bone mineral density among women: a cross-sectional survey

OBJECTIVE: We examined the association between total tooth loss and bone mineral density to determine whether the former can be used as a surrogate marker of the latter. DESIGN: A community based cross-sectional survey. SETTING: The community-study area of the Faculty of Medicine, Galle. PARTICIPANTS: A group of randomly selected 327 women volunteers aged 32 to 97 years. MEASUREMENTS: Anthropometr

Fakultetsopponenten sammanfattar: Josefin Brüde Sundins En riktig rektor. Om ledarskap, genus och skolkulturer

Den utbildningsvetenskapliga forskningen har ofta en normativ ton och lanserar idéer om hur skolan borde vara, hur undervisning borde bedrivas, hur människor borde lära och om hur skolor borde ledas. Utbildningsvetenskaplig forskning skulle tjäna på att vara mindre normativ och mer empirisk och analytisk. I doktorsavhandlingen En riktig rektor. Om ledarskap, genus och skolkulturer, som Josefin Brü