Whatever happened to cybernetics in architecture? Cybernetics was swaggering from day one. Its original mission, to predict the evasive manoeuvres of bomber pilots, soon evolved into making predictions in social systems and game theory. In the early 1960s, cybernetics began to make inroads into architecture, famously so in the never-realised Fun Palace, designed by architect Cedric Price, theatre

We present Titta, an open-source toolbox for controlling eye trackers manufactured by Tobii AB from MATLAB and Python. The toolbox provides a wrapper around the Tobii Pro SDK, providing a convenient graphical participant setup, calibration and validation interface implemented using the PsychToolbox and PsychoPy toolboxes. The toolbox furthermore enables MATLAB and Python experiments to communicate

Living systems integrate biochemical reactions that determine the functional state of each cell. Reactions are primarily mediated by proteins. In proteomic studies, these have been treated as independent entities, disregarding their higher-level organization into complexes that affects their activity and/or function and is thus of great interest for biological research. Here, we describe the imple

With increasing demand for high-resolution X-ray images, the super-resolution method allows to estimate a single high-resolution image from several low-resolution images. Hybrid pixel detectors provide high-quality and low-resolution images, which makes them particularlywell suited for super-resolution. However, such detectors consist of a limited number of pixels at high cost. Applying super-reso

Repair of injured peripheral nerve trunks in the hand and upper extremity still represents one of the most challenging surgical constructive problems. In adults, discriminative sensory functions of the hand do not usually recover despite use of microsurgical repair techniques. A major reason for the imperfect outcome is the pronounced functional cortical reorganizations that occur after nerve inju

To better understand the historical gender wage gap, we investigate the wages of Swedish compositors circa 1900 using a rich data set of matched employer-employee information with national coverage. In line with previous findings, women earned about 70 percent of men’s wages on average. Individual and job characteristics explain much of this shortfall. Firm characteristics or firm fixed effects, o

Background: As part of I-O Optimise, a multinational research platform providing real-world insights into the management of lung cancers, the SCAN-LEAF study aims to describe the epidemiology, clinical care, and outcomes for pts with NSCLC in Scandinavia. Here, we report temporal OS trends among pts diagnosed with incident NSCLC from 2005 to 2015 in Denmark and Sweden. Methods: The SCAN-LEAF Danis

Background: As part of I-O Optimise, a multinational research platform providing real-world insights into the management of lung cancers, the SCAN-LEAF study aims to describe the epidemiology, clinical care and outcomes for pts with NSCLC in Scandinavia. We report initial Tx and OS for pts with NSCLC prior to the availability of immunotherapies in Sweden. Methods: The analysis includes all adult p

Agricultural intensification and associated loss of high-quality habitats are key drivers of insect pollinator declines. With the aim of decreasing the environmental impact of agriculture, the 2014 EU Common Agricultural Policy (CAP) defined a set of habitat and landscape features (Ecological Focus Areas: EFAs) farmers could select from as a requirement to receive basic farm payments. To inform th

This guideline aims to describe the complement system and the functions of the constituent pathways, with particular focus on primary immunodeficiencies (PIDs) and their diagnosis and management. The complement system is a crucial part of the innate immune system, with multiple membrane-bound and soluble components. There are three distinct enzymatic cascade pathways within the complement system,