Filetype
Investigating epidemiology of metastatic colon and rectal cancer is challenging, because cancer registries seldom record metastatic sites. We used a population based approach to assess metastatic spread in colon and rectal cancers. 49,096 patients with colorectal cancer were identified from the nationwide Swedish Cancer Registry. Metastatic sites were identified from the National Patient Register
The introduction of proteasome inhibitors in the treatment of multiple myeloma (MM) patients has been a therapeutic success. Peripheral neuropathy (PNP) remains one of the most frequent side-effects experienced by patients who receive these novel agents. Recent investigations on the mechanisms of PNP in patients treated with bortezomib have suggested genetic susceptibility to neurotoxicity. We use
We numerically compute the low-energy spectrum of a gate-controlled superconducting topological nanowire segmented into two islands, each Josephson coupled to a bulk superconductor. This device may host two pairs of Majorana bound states and could provide a platform for testing Majorana fusion rules. We analyze the crossover between (i) a charge-dominated regime utilizable for initialization and r
Thin films of "complex salts" (CS = ionic surfactants with polymeric counterions) have recently been shown to respond to humidity changes in ambient air by changing their liquid crystalline structure. We here report isotherms and kinetics of water sorption/desorption for ∼10-100 μm films of alkyltrimethylammonium polyacrylate CS, measured in a dynamic gravimetric vapor sorption instrument over a 0
Changes in vehicle emission reduction technologies significantly affect traffic-related emissions in urban areas. In many densely populated areas the amount of traffic is increasing, keeping the emission level high or even increasing. To understand the health effects of traffic-related emissions, both primary (direct) particulate emission and secondary particle formation (from gaseous precursors i
Grid connected renewable energy systems are becoming popular due to reasons such as rapid escalation of energy prices, depletion of fossil fuel resources and pollutant emitted by conventional energy sources. Therefore, technologies for incorporating renewable energy technologies into the existing electricity grid needs to be researched more considering the changes in grid architecture. This study
Integrating renewable energy technologies based on solar PV (SPV) and wind energy in the energy system is challenging due to time dependence of the energy potential for these energy sources. Grid integrated hybrid energy systems combining SPV panels, wind turbines, battery bank and internal combustion generators (ICG) can be used in this regard specially for distributed generation. Energy-economic
Current manuscript gives a synopsis of tumor heterogeneity related to patient samples analyzed by proteomics, protein expression analysis and imaging mass spectrometry.First, we discuss the pathophysiologocal background of cancer biology as a multifactorial and challenging diseases. Disease pathology forms the basis for protein target selection. Therefore, histopathological diagnostics and grading
The European species of Foersterella Dalla Torre 1897 (Hymenoptera: Tetracampidae) are treated, including two previ-ously described species, F. erdoesi Bouček and F. reptans (Nees), and two new species, F. angusticornis sp. nov. and F. fuscicornis sp. nov. Morphological concepts of the species are based mainly on characters in the male antenna, which fe-males lack, and with the exception of F. erd
Arktiska miljöer har de senaste decennierna upplevt en stark temperaturökning, vilket påverkar tundrans kolcykel.Smältande permafrost, minskande snötäcke och förändringar i hydrologiska mönster är exempel på pågående processer som förändrar samspelet mellan mark och atmosfär samt ekosystemens säsongsdynamik.Då ett antal av dessa processer involverar utbyte av växthusgaser, såsom spårgaserna metan Arctic environments have experienced strong warming in recent decades, which is affecting the carbon cycle of tundra ecosystems.Degrading permafrost, diminishing snow cover, and changing hydrology are examples of ongoing processes that affect the land-atmosphere interactions and seasonal ecosystem dynamics.Since a number of the affected processes involve the exchange of atmospheric greenhouse gase
Nine species in five genera of the family Axinellidae, including three new species, Axinella badungensis sp. nov., A. ba-linensis sp. nov. and Phycopsis pesgalli sp. nov. are recorded from Indonesian waters within the limits of the Western Coral Triangle province. Descriptions and discussion of those species are presented here. Four new combinations, Pha-kettia arbora (Sim, Kim & Byeon, 1990)
We present an overview of the studies of ion pairing in aqueous media of the past decade. In these studies, interactions between ions, and between ions and water, are investigated with relatively novel approaches, including dielectric relaxation spectroscopy, far-infrared (terahertz) absorption spectroscopy, femtosecond mid-infrared spectroscopy, and X-ray spectroscopy and scattering, as well as m
A 9-month lab experiment was carried out with three different amendments (vine pruning wastes, PW; composted vine pruning wastes, cPW; and sewage sludge, SS) added at three different rates (90, 180, and 240 t ha−1, dry weight) in order to test whether the type or the quantity of the amendments applied to a semiarid, degraded soil determined the Corg accumulation in its particle-size fractions (coa
BACKGROUND: Acute dyspnea affects a large heterogeneous patient group with high mortality and readmission rates.PURPOSE: To investigate if cardiometabolic biomarkers and clinical characteristics predict readmission and death in patients hospitalized for acute dyspnea.METHODS: 65 dyspnea patients at a general internal medicine ward were followed for six months. The combined endpoint was readmission
Snow cover is one of the key factors controlling Arctic ecosystem functioning and productivity. In this study we assess the impact of strong variability in snow accumulation during 2 subsequent years (2013-2014) on the land-atmosphere interactions and surface energy exchange in two high-Arctic tundra ecosystems (wet fen and dry heath) in Zackenberg, Northeast Greenland. We observed that record-low
Atmospheric particulate matter is one of the main factors governing the Earth's radiative budget, but its exact effects on the global climate are still uncertain. Knowledge on the molecular-scale surface phenomena as well as interactions between atmospheric organic and inorganic compounds is necessary for understanding the role of airborne nanoparticles in the Earth system. In this work, surface c
Amylin, a pancreatic β-cell-derived peptide hormone, forms inclusions in brain microvessels of patients with dementia who have been diagnosed with type 2 diabetes and Alzheimer's disease. The cellular localization of these inclusions and the consequences thereof are not yet known. Using immunohistochemical staining of hippocampus and parahippocampal cortex from patients with Alzheimer's disease an
