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An evidence-based approach to forensic life-threat assessments using spleen injuries as an example

INTRODUCTION: During the judicial process of addressing violent crime, a forensic practitioner may need to assess whether an inflicted injury should be considered life-threatening. This could be important for the classification of the crime. To some extent, these assessments are arbitrary since the natural course of an injury might not be completely known. To guide the assessment, a quantitative a

Framing Positive Obligations under the European Convention on Human Rights Law: Mediating between the Abstract and the Concrete

This article examines positive obligations under the European Convention on Human Rights from the perspective of the level of concreteness chosen for their framing. This level is essential for understanding whether and how the analytical distinction between the existence of an obligation and the breach of this obligation can be applied. The level of concreteness is an important conceptual framewor

Changes to consultations and diagnosis of osteoarthritis in primary care during the COVID-19 pandemic

OBJECTIVE: General practitioners (GP) are often the first medical professionals to treat musculoskeletal complaints. Yet the impact of COVID-19 on primary care utilisation for musculoskeletal complaints is largely unknown. This study quantifies the impact of the pandemic on primary care utilisation for musculoskeletal complaints and specifically osteoarthritis (OA) in the Netherlands.DESIGN: We ex

Cardiac Asystole at Birth Re-Visited : Effects of Acute Hypovolemic Shock

Births involving shoulder dystocia or tight nuchal cords can deteriorate rapidly. The fetus may have had a reassuring tracing just before birth yet may be born without any heartbeat (asystole). Since the publication of our first article on cardiac asystole with two cases, five similar cases have been published. We suggest that these infants shift blood to the placenta due to the tight squeeze of t

Follow-up and screening for type-2 diabetes mellitus in women with previous gestational diabetes in primary care

ObjectiveGestational diabetes mellitus (GDM) is an established risk factor for developing type 2 diabetes mellitus (T2DM) that is possible to prevent by systematic follow-up and preventive measures. The aim of this study was to examine whether women with previous GDM were offered follow-up in primary care, according to Swedish national guidelines.DesignRetrospective review of electronic medical re

Integration of ground-source heat pumps in combined district heating and cooling networks: A holistic modeling framework

The integration of heat pumps in low-enthalpy district heating and cooling networks can increase the efficiency and flexibility of the network. In such systems, heat pumps are installed both locally and centrally to serve different functions. In the former case, decentralized heat pumps at each building adjust the low-network temperature to the desired supply temperature. In the latter case, a cen

A new vegetation index combination for leaf carotenoid-to-chlorophyll ratio : minimizing the effect of their correlation

The ratio of leaf carotenoid to chlorophyll (Car/Chl) is an indicator of vegetation photosynthesis, development and responses to stress. However, the correlation between Car and Chl, and their overlapping absorption in the visible spectral domain pose a challenge for optical remote sensing of their ratio. This study aims to investigate combinations of vegetation indices (VIs) to minimize the influ

Biofilm formation is associated with poor outcome in prosthetic joint infections caused by Staphylococcus lugdunensis

Background: Staphylococcus lugdunensis has been described as a pathogen of increasing importance in prosthetic joint infections (PJI). Our aim was to describe the clinical presentation of PJI caused by S. lugdunensis, and to correlate the biofilm-forming ability of the bacterial isolates to clinical outcome. Method: S. lugdunensis isolates from PJI episodes during 2015–2019 were included and analy

Sex hormone-dependent and-independent regulation of serum BAFF and TNF in cohorts of transgender and cisgender men and women

Background: The risk of inflammatory diseases is sex-dependent, but it remains unknown whether this is due to the impact of sex hormones or sex chromosomes. Transgender individuals represent a unique cohort for studying the relative influence of endocrine and chromosomal factors. Here we compared serum levels of B-cell activating-factor (BAFF) and tumor necrosis factor (TNF) in transgender men (TM

Contribution of carbon pricing to meeting a mid-century net zero target

A mid-century net zero target creates a challenge for reducing the emissions of emissions-intensive, trade-exposed sectors with high cost mitigation options. These sectors include aluminium, cement, chemicals, iron and steel, lime, pulp and paper and petroleum refining. Available studies agree that decarbonization of these sectors is possible by mid-century if more ambitious policies are implement

Sex differences in multilayer functional network topology over the course of aging in 37543 UK Biobank participants

Aging is a major risk factor for cardiovascular and neurodegenerative disorders, with considerable societal and economic implications. Healthy aging is accompanied by changes in functional connectivity between and within resting-state functional networks, which have been associated with cognitive decline. However, there is no consensus on the impact of sex on these age-related functional trajector

Fear and anxiety differ in construal level and scope

The fear-anxiety distinction has been extensively discussed and debated among emotion researchers. In this study, we tested this distinction from a social-cognitive perspective. Drawing on construal level theory and regulatory scope theory, we examined whether fear and anxiety differ in their underlying level of construal and scope. Results from a preregistered autobiographical recall study (N = 2

Hallmarks and potential pitfalls of customer- and consumer engagement scales : A systematic review

Multiple scales measuring a customer's, or consumer's, engagement (CE) with a brand or specific brand elements (e.g., advertising/social media content) have been proposed in the literature, offering researchers different options to gauge CE. However, the myriad proposed operationalizations can yield confusion among scholars regarding how to best capture CE, exposing a growing issue for CE research

The National Prevalence of Clinically Diagnosed Psoriatic Arthritis in Sweden in 2017

Objective. Psoriatic arthritis (PsA) prevalence estimates vary across studies; studies based on national data are few. We aimed to estimate the prevalence of clinically diagnosed PsA in Sweden in 2017, overall and stratified by sex, age, education, and geography, and to quantify disease-modifying antirheumatic drug (DMARD) use among those in contact with specialized rheumatology care between 2015