Effect of individualized anesthesia and analgesia on postoperative pain in patients stratified for pain sensitivity : A study protocol for the PeriOPerative individualization trial randomized controlled trial
BACKGROUND: Despite advancements in surgical and anesthesia techniques, acute and persistent postoperative pain are still a common challenge. Postoperative pain has direct effects on individual patient care and outcome, as well as putting strain on limited health care resources. Several prediction methods for postoperative pain have been described. One such method is the assessment of pain during