Background: Bladder cancer is molecularly one of the most heterogenous malignancies characterized by equally heterogenous clinical outcomes. Standard morphological assessment with pathology and added immunohistochemical analyses is unable to fully address the heterogeneity, but up to now treatment decisions have been made based on such information only. Bladder cancer molecular subtypes will likel

Quaternary Asian low-latitude hydroclimate cyclicity has long been attributed to insolation forcing, in contrast to the dominant ice-sheet and CO2 controls identified in mid-high-latitude regions. However, debates exist regarding these rainfall variations and forcings due to inconsistent reconstructions and simulations. Here, by combining rainfall proxy records with multi-model simulations, domina

The high brilliance and coherent beams resulting from recent upgraded synchrotron radiation facilities open the way for a large range of experiments, where detectors play a key role in the techniques and methods developed to fully exploit the upgraded synchrotron. For instance, one of the major limitations of XAFS experiment is the performance of the detectors. In order to be able to measure more

An innovative design of microbial electrolytic reactor (MER) coupled with Ipomoea aquatica Forsk. plant microbial fuel cell (IAF-PMFC) was developed for azo dye wastewater treatment and electricity generation. This study aims to assess the sequential degradation of azo dye and the feasibility of energy self-sufficiency in the MER/IAF-PMFC system. The decomposition of azo dye into aromatic amines a

In recent years, school strikes and street protests for climate justice have drawn international attention to young people's mobilisation and activism on global issues. This article addresses the need to map the history of global awareness among young people by exploring the origins of the Operation Dagsverke (Operation Day's Work) campaign in Sweden during the early 1960s. Drawing primarily on ma

In this article, I challenge the increasing emphasis on digital technologies to enhance encounters with the past in heritage landscapes. Beginning with a memory from my childhood, I conceptualise presence as being there and review recent approaches in heritage studies that highlight the wide range of benefits derived from embodied experiences in heritage places including reinforcing feelings of we

This paper investigates an integrated traffic environment modeling and model predictive control (MPC) system to realize interaction-aware dynamic motion planning of an autonomous vehicle with multiple surrounding vehicles. The interaction-aware interacting multiple model Kalman filter (IAIMM-KF) from the literature is used to hierarchically predict maneuvers and trajectories of surrounding vehicle

Purpose: The purpose of the study was to describe the design and implantation of a branched stent-graft during endovascular aortic repair incorporating double-cuff bidirectional inner branch. Technique: A new double-cuff bidirectional antegrade and retrograde inner branched stent-graft with large diamond-shaped fenestration was designed for incorporation of a splenic artery. The inner cuffs of the

In this study, a synthesis process based on the microemulsion method (ME) was developed with the aim to produce controlled-size starch nanoparticles (SNPs). Several formulations were tested for the preparation of the W/O microemulsions varying the organic/aqueous phase ratios and co-stabilizers concentrations. SNPs were characterized in terms of size, morphology, monodispersity and crystallinity.

The preservation of labile biomolecules presents a major challenge in chemistry, and deep eutectic solvents (DESs) have emerged as suitable environments for this purpose. However, how the hydration of DESs impacts the behavior of proteins is often neglected. Here, we demonstrate that the amino acid environment and secondary structure of two proteins (bovine serum albumin and lysozyme) and an antib

Acquired haemophilia A (AHA) is a rare bleeding disorder caused by acquired antibodies against coagulation factor VIII. In the Nordic countries, treatment and outcomes have not been studied in recent times. To collect retrospective data on patients diagnosed with AHA in the Nordic countries between 2006 and 2018 and compare demographic data and clinical outcomes with previously published reports,

This chapter describes a preliminary study of sustainable social progress in the Kingdom of Tonga conducted following the 2009 report and recommendations of the Commission on the Measurement of Economic Performance and Social Progress (CMEPSP). Tonga appears to be making reasonable social progress according to GDP, the Human Development Index and Millennium Development Goals metrics. However, clos

Permanent deformation is the primary failure mode for the asphalt concrete (AC) pavement in urban environment. It is mainly caused by a combination of heavy traffic load, low vehicle speed and channelised traffic. A rut prediction model would therefore be a valuable tool for planning maintenance scheduling and selecting an appropriate asphalt material. This study uses the PEDRO (Permanent deformat

This article introduces the Framework for Integrating Rights and Equality (FIRE): a transdisciplinary framework that builds synergies between human rights-based (HRBA) and gender equality approaches to disaster risk reduction (DRR) and climate change adaptation (CCA). It describes how FIRE has been developed, tested and refined over the course of a five-year regional learning and technical coopera

There have been significant advances in the field of nanofluidics, and novel technologies such as single-cell analysis have been demonstrated. Despite the evident advantages of nanofluidics, fluid control in nanochannels for complicated analyses is extremely difficult because the fluids are currently manipulated by maintaining the balance of driving pressure. To address this issue, the use of valv

Recent research has revealed that interdisciplinary work combining archaeological and heritage practice continues to be limited by enduring assumptions separating the two fields. Traditional structures and institutional barriers make it difficult to break away from what is expected in order to explore what is possible in what archaeologists and heritage practitioners ‘do’. Though archaeologists pl

Enligt Världshälsoorganisationen finns ett globalt underskott på utbildade sjuksköterskor. Även i Sverige är vårdpersonal som undersköterskor och sjuksköterskor ett bristyrke med en begränsad löneutveckling. Denna studie undersökte undersköterskor och sjuksköterskor inom den offentliga sektorn i Sverige (N = 139). Via en digital enkät undersöktes deltagarnas intentioner att stanna eller lämna sin According to the World Health Organization, educated nurses need to increase all around the world. Assistant nurses and nurses are a deficit profession in Sweden with a limited salary trend. The aim of the study was to see how inclined participants were to stay or leave the current workplace, to explore psychological safety, job satisfaction and to what extent these factors are associated with int