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Among the responders to microbial invasion, neutrophils represent the earliest and perhaps the most important immune cells that contribute to host defense with the primary role to kill invading microbes using a plethora of stored anti-microbial molecules. One such process is the production of reactive oxygen species (ROS) by the neutrophil enzyme complex NADPH-oxidase, which can be assembled and a

Abstract in GreekΠερίληψηΟ Μηχανισμός των Αντικυθήρων αποτελεί ένα μοναδικό εύρημα. Η έρευνά του απασχολεί επιστήμονες προερχόμενους από ένα ευρύ φάσμα ειδικοτήτων και τα αποτελέσματά της φανερώνουν τον ανεπτυγμένο βαθμό της επιστημονικής εξέλιξης της εποχής, που κατασκευάστηκε ο Μηχανισμός, ξαναγράφοντας την ιστορία της τεχνολογίας. Μετά από έναν και πλέον αιώνα από την εύρεση του, αρχαιολόγοι επ

Den digitala utvecklingen har gått mycket snabbt vilket omvärlden på flera sätt har varit tvungen att anpassa sig efter. En åtgärd från den Europisks unionens sida som har vidtagits i försök att anpassa sig är framtagandet av GDPR. GDPR syftar bland annat till att skydda person-lig integritet genom att reglera behandling av personuppgifter. I denna uppsats har fokus legat på att undersöka hur tillThe digital development has progressed rapidly, which the surrounding world has had to adapt to in several ways. One measure taken by the European Union to adapt, is the development of GDPR. GDPR aims, among other things, to protect personal integrity by regulating the processing of personal data. The objective of this paper has been to investigate the lawful basis "legitimate interest&qu

Saliva plays a crucial role in maintaining oral health through its physical and chemical properties that provide various protective functions. One of its essential components is the human host defense peptide LL-37, which is produced by immune cells and epithelial cells, and participates in the first line of defense against pathogens. LL-37 is a potent antimicrobial agent against both gram-positiv

Through the advent of high-order harmonic generation and attosecond light pulses, photoionization dynamics has been studied on the attosecond time-scale, the intrinsic time-scale of such dynamics. When the electron leaves the atomic potential a phase shift is imprinted on the electron wavefunction. The measurement of this phase, together with amplitude allows us to determine the dynamics that of t

Bostäder i storstäder har blivit en svårtillgänglig lyxvara, samtidigt som ett fåtal tjänar mycket pengar på situationen. Som bostadsmarknaden ser ut idag, med vinstdrivande byggbolag tillsammans med dyr mark, går problemet inte att lösa utan förändring (Länsstyrelsen 2021). Detta examensarbete söker efter ett alternativt sätt att bo där de boende tillsammans tar kontroll över sin boendesituation.Housing in big cities has become a luxury that many people cannot afford, while a few make a lot of money out of the situation. As the housing market stands today, with profit-driven construction companies and expensive land, the problem cannot be solved without change (Länsstyrelsen 2021). This thesis seeks an alternative way of living, where the residents together take control of their housing s

Detta är en bearbetad version på nederländska av min tidigare på svenska utgivna biografi om den engelske kungen Henrik VIII.De Zweedse hoogleraar Dick Harrison vertelt het kleurrijke levensverhaal van Hendrik VIII (1491-1547). Hendrik werd, na de dood van zijn vader, de tweede Tudor-koning van Engeland. Hij leidde een roemrucht bestaan. Hij had zes echtgenotes, van wie hij er twee liet onthoofden. Hij scheidde, voor eigen gewin, de Anglicaanse kerk af van de Kerk van Rome, en hij verenigde Engeland en Wales wettelijk i

The currant bud moth Euhyponomeutoides albithoracellus is a destructive pest in black currant orchards in Northern Sweden and Finland. The larvae feed on the buds, and at high densities, the species can cause severe yield losses. Sex pheromone components of the bud moth were identified via solvent extraction of excised female pheromone glands, analyses by gas chromatography with electroantennograp

Volatile fatty acids (VFAs) are key platform chemicals used in a multitude of industries including chemicals, pharmaceuticals, food and agriculture. The current route for VFA production is petrochemical based. VFAs can be biologically produced using organic wastes as substrate, therefore directly contributing to a sustainable economy. This process is commonly known as acidogenic fermentation (AF).

The host Maria Bach speaks to Evelina Kallträsk, David Larsson Heidenblad, Anna Nilsson Hammar and Johan Östling about the history of knowledge and how its approaches might be useful for historians of economics.In a new episode of the podcast Ceteris Never Paribus, the host Maria Bach speaks to Evelina Kallträsk, David Larsson Heidenblad, Anna Nilsson Hammar and Johan Östling, all members of the Lund Centre for the History of Knowledge (LUCK). They discuss what is the history of knowledge and how its approaches might be useful for historians of economics.

The relationship between state and civil society organisations is a well studied area within the field of political science in the Swedish contemporary political context. While the focus has previously largely been on producer-organisations and their politically privileged position, the resent additional focus has been on the civil society organisation defined by social-movements-oriented organisa

Aims/hypothesisPPARGC1A encodes peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α), a central regulator of energy metabolism and mitochondrial function. A common polymorphism in PPARGC1A (rs8192678, C/T, Gly482Ser) has been associated with obesity and related metabolic disorders, but no published functional studies have investigated direct allele-specific effects in adipocyte bi

The productivity of the Acetone Butanol Ethanol (ABE) fermentation can be significantly increased by application of various in situ product recovery (ISPR) techniques. There are numerous technically viable processes, but it is not clear which is the most economically viable in practice. There is little available information about the energy requirements and economics of ISPR for the ABE fermentati

Clonal hematopoiesis of indeterminate potential (CHIP) is a common form of age-related somatic mosaicism that is associated with significant morbidity and mortality. CHIP mutations can be identified in peripheral blood samples that are sequenced using approaches that cover the whole genome, the whole exome, or targeted genetic regions; however, differentiating true CHIP mutations from sequencing a

During the last few decades, satellite remote sensing has proven to be an important non-invasive method for archaeological research in order to detect ancient sites and manage existing ones. Archaeologists have tried in the recent past to embed Geographic Information Systems (GIS) and image processing techniques in their research as non-destructive approaches, which can allow a wider perception o

Context: Rivers are heterogeneous landscapes characterised by distinct patches separated by boundaries. The significance of tributaries as dominant geomorphic boundaries in determining the character of the river discontinuum is a prevailing, yet largely unscrutinised, paradigm of river science. Objectives: This study examines the spatial organisation and strength of geomorphic boundaries within th

Background: No targeted drugs are currently available against small cell lung cancer (SCLC). BCL-2 family members are involved in apoptosis regulation and represent therapeutic targets in many malignancies. Methods: Expression of BCL-2 family members in 27 SCLC cell lines representing all known four SCLC molecular subtypes was assessed by qPCR, Western blot and mass spectrometry-based proteomics.

Background: A high level of competence among staff is necessary for providing patient-safe surgical care. Knowledge regarding what factors contribute to the professional development of specialist nurses in surgical care and why they choose to remain in the workplace despite high work requirements is needed. To investigate and describe the organizational and social work environment of specialist nu