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Polygenic scores of diabetes-related traits in subgroups of type 2 diabetes in India: a cohort study

BackgroundA machine-learning approach identified five subgroups of diabetes in Europeans which included severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), mild obesity-related diabetes (MOD) and mild age-related diabetes (MARD) with partially distinct genetic aetiologies. We previously validated four of the non-autoimmune subgroup

Age and Referral Route Impact the Access to Diagnosis for Women with Advanced Ovarian Cancer

Purpose: The majority of women with ovarian cancer are diagnosed in late stages. Most women do have symptoms prior to diagnosis, sometimes several months before the diagnosis. The aim of this study was to evaluate the timeline from the first presentation of symptoms to a physician until there is a reasonable suspicion of cancer, among women diagnosed with advanced stage ovarian cancer. We wanted t

Morphological development of a small-scale beach nourishment in a non-tidal area

Combining hard and soft costal protection solutions can be an appropriate measure to enhance structure lifetime. This study aims to quantify the morphological evolution of the nourished stretch and adjacent coastlines. A small-scale beach nourishment has been performed in front of a rock revetment at site in Faxe Ladeplads in Zealand, Denmark. The overall objective is to learn more about the dynam

More Theory for Mortuary Research of the VikingWorld

This themed journal issue provides many examples of ways forward in the study of death and memory in the Viking world. While all contributions demonstrate that there are exciting new ways to study remains from funerary contexts that focus on different forms of citation involving material culture and monuments, this article will very briefly discuss dimensions that have not been addressed here. Spe

The impact of immunomodulating treatment on the immunogenicity of COVID-19 vaccines in patients with immune-mediated inflammatory rheumatic diseases compared to healthy controls. A Swedish nationwide study (COVID19-REUMA)

OBJECTIVES: To elucidate antibody responses after the second and third dose of COVID-19 vaccine in patients with inflammatory rheumatic diseases (IRD) treated with biologic/targeted disease modifying anti-rheumatic drugs (b/ts DMARDs).METHODS: Antibody levels to antigens representing spike full length protein and spike S1 were measured before vaccination, 2-12 weeks after the second dose, before a

Do Exporters Import Gender Inequality?

We examine whether exposure to gender inequality at export destinations affects the gender wage gap in exporting firms. We motivate the analysis through a stylized model where wages depend on worker productivity, and men have a comparative advantage when trading with gender-unequal countries due to customer discrimination. Empirically, we use high-quality matched employer-employee data from Sweden

UK Hansard 1935-2014

This corpus is based on the Rheault version and is reproduced with his written permission. The original corpus contained the following columns: cabinet function parliament party party_in_power speaker_id speech_id speech_text topic yearTo which we have added the following columns: date times_in_house seniority district district_class

Arabinoxylan and its potential role in lowering the glycaemic index

Oat (Avena sativa) is a cereal crop rich in dietary fibre, vitamins, antioxidants and other nutrients. It is considered to have higher nutritional values compared to other cereals (Tosh & Miller, 2016). Arabinoxylan (AX) is a hemicellulose naturally abundant in cereal crops. It is a major component of dietary fibre in crops like wheat, barley, rye, maize, rice and oats (Lu et al., 2000). Stu

High arabinoxylan oat lines characterization: structural properties and heat-treatment effect

Arabinoxylan (AX) is a beneficial dietary fibre found in cereals such as oats. This crop also possesses high quality proteins and other fibres like b-glucan that help reduce LDL and postprandial blood glucose levels. Lines with a higher content of AX have been recently identified, and the current study aimed to investigate the structure of the AX fibre in these lines in comparison to the commercia

Empirical challenges from the comparative and developmental literature to the Shared Intentionality Theory : A review of alternative data on recursive mind reading, prosociality, imitation and cumulative culture (Part 2)

Humans have an irresistible inclination to coordinate actions with others, leading to species-unique forms of cooperation. According to the highly influential Shared intentionality theory (SITh), human cooperation is made possible by shared intentionality (SI), typically defined as a suite of socio-cognitive and motivational traits for sharing psychological states with others, thereby enabling ind

Dual-Band Infrared Scheimpflug Lidar Reveals Insect Activity in a Tropical Cloud Forest

We describe an entomological dual-band 808 and 980 nm lidar system which has been implemented in a tropical cloud forest (Ecuador). The system was successfully tested at a sample rate of 5 kHz in a cloud forest during challenging foggy conditions (extinction coefficients up to 20 km–1). At times, the backscattered signal could be retrieved from a distance of 2.929 km. We present insect and bat obs

The Brexit battle on Facebook: assessing echo chambers and polarisation

Does online campaigning foster ‘echo chambers’ and exacerbate the polarisation of society? On Facebook, Leave and Remain supporters behaved very differently. Pro-Remain users commented mainly on like-minded Facebook pages. By avoiding confrontation with their political opponents, Remainers showed behaviour characteristic of an ‘echo chamber’. In contrast, Leavers spread their messages on pages spa

Symmetric doubly periodic gravity-capillary waves with small vorticity

We construct small amplitude gravity-capillary water waves with small nonzero vorticity, in three spatial dimensions, bifurcating from uniform flows. The waves are symmetric, and periodic in both horizontal coordinates. The proof is inspired by Lortz' construction of magnetohydrostatic equilibria in reflection-symmetric toroidal domains. It relies on a representation of the vorticity as the cross

System and method for performing motion-insensitive and quiet three-dimensional magnetic resonance imaging

A method for generating motion-corrected medical images includes obtaining, via a processor, k-space data of a region of interest acquired by a magnetic resonance imaging system utilizing a 3D radial pulse sequence with ZTE acquisition including optional magnetization preparation pulses. The method also includes sampling, via the processor, the k-space data to obtain a plurality of interleaved k-s