To examine whether altered gene expression of insulin receptor substrates (IRS)-1 and IRS-2 and Src homologous and collagen-like protein Shc is an inherited trait and is associated with muscle insulin resistance or type 2 diabetes, we measured mRNA levels of these genes by a relative quantitative RT-PCR method in muscle biopsies taken before and after an insulin clamp from 12 monozygotic twin pair

Hematopoietic stem cells (HSCs) are primitive tissue-specific somatic stem cells, responsible for the maintenance and replenishment of the bone marrow (BM) and subsequently the entire blood system. The never-ending ability to differentiate into all the mature hematopoietic lineages makes these HSCs attractive candidates for use in future regenerative medicine. HSCs are balanced between different f

The two nuclei Cd-98 and Sn-102, closest neighbours of Sn-100, have been studied with a recoil catcher setup, following the reactions: Ni-58(Ti-46, alpha 2n)Cd-98 and Ni-58(Cr-50, alpha 2n)Sn-102. Long lived isomeric states were measured in Cd-98 I-pi = (8+), t(1/2) = 0.48(8) mu s and in Sn-102 I-pi = (6(+)) with t(1/2) = 1.0(6) mu s. The proposed experimental level schemes of the isomeric decay a

Pioneering work in the last century has resulted in a widely accepted paradigm that primary production is strongly positively related to temperature and water availability such that the northern hemispheric forest carbon sink may increase under conditions of global warming. However, the terrestrial carbon sink at the ecosystem level (i.e. net ecosystem productivity, NEP) depends on the net balance

Background: Gastrectomy, specifically the removal of the acid-producing part of the stomach (fundectomy), is known to cause osteopenia. This effect has been ascribed to the elimination of a hypothetical osteotropic peptide hormone, presumably produced in the oxyntic mucosa. Since osteopenia is due to a disturbed balance between bone formation and resorption, we assessed the effect of gastrectomy o

A 10-bit 5-MS/s successive approximation ADC cell and a 70-MS/s parallel ADC array based on this cell, designed and fabricated in a 1.2-?m CMOS process, are presented. The ADC cell was designed to have an input bandwidth of more than 35 MHz and a sampling time of 14 nS at a clock rate of 70 MHz. The parallel ADC array consists of 14 such cells which are timed in one clock cycle skew successively i

REX-ISOLDE is an experiment at ISOLDE/CERN with the aim to study the nuclear structure of neutron-rich nuclei using radioactive ion beams up to 2.2 MeV/u. The highly-efficient gamma-ray detector set-up MINIBALL will be used to explore reactions induced by Coulomb excitation or neutron transfer.

Purpose: Interstitial temperature mapping was used to determine the heat field within the prostate by the Coretherm. (ProstaLund, Lund, Sweden) transurethral microwave thermotherapy device. Gadolinium. enhanced magnetic resonance imaging (MRI) and histopathology were used to determine the extent and pattern of coagulation necrosis following treatment. The cell kill assessment feature of the device

In this paper, enhancement of the signal root estimation of a particular kind of real-valued two-dimensional (2-D) sinusoidal modes is considered. To its constitution, each mode corresponds to the superposition of two real-valued plane waves in a particular symmetry. The concept of partial forward-backward averaging, which is applicable for modes that are undamped in at least one dimension, is int

Analys av den brittiska science fiction-filmen under 1960- och 1970-talen med filmen Moon Zero Two som exempel.

Popular Abstract in Swedish Det övergripande syftet för denna avhandling är att bland patrullerande poliser undersöka förekomst och karaktär av en yrkeskultur, som går utöver eller står i motsättning till polisens officiellt sanktionerade samhällsmandat bl.a. i termer av den inriktning, de prioriteringar och det regelverk som omger polisarbetet. Begreppet yrkeskultur står här för kollektiva mönsteUsing ethnographical methods, this thesis examines the prevalence and character of an occupational culture among patrolling police in terms of frames of reference, conduct and attitudes, a culture which overrides or is in opposition to the official mandate of the police force. It is suggested that the occupational culture of the patrolling police should not be regarded as a homogenous culture but

The antigen-binding site, the paratope, of an antibody can be seen as being composed of a central core and a more peripheral area situated at its rim. Naturally these regions acquire their diversity using different mechanisms and they also have dissimilar roles, as they contribute differently to the binding interaction. Also, antigens of different size utilize these regions differently; while hapt