Search results

Filter

Filetype

525042 hits

Muscle mass, creatinine, cystatin C, and selective glomerular hypofiltration syndromes

In this issue of Clinical Kidney Journal, Stehlé and colleagues demonstrate that estimation of glomerular filtration rate (GFR) by use of creatinine and a measure, total lumbar muscle cross-sectional area, reflecting the total muscle mass of an individual, is superior to GFRestimating equations based upon creatinine and demographic variables. The report by Stehlé et al demonstrates one solution to

A Reconfigurable RF Filter With 1%–40% Fractional Bandwidth for 5G FR1 Receivers

This letter presents a radio frequency front-end (RFFE) for 5G new radio (NR) receivers operating in frequency range 1 (FR1). The core of this RFFE is a synthetic fourth-order Q -enhanced RF filter employing gm -boosting, noise-canceling, capacitive cross-coupling, and forward body-biasing techniques to achieve 1.7 to 6.4 GHz operating range and 1% to 40% adjustable fractional bandwidth (FBW). The

Are local fisheries important for marine tourism? A case study of the Swedish fishing village Träslövsläge

Coastal fishing fleets are declining in many parts of Europe. In Sweden, this has left many traditional fishing harbours with no or very few active fishers. This might have effects on the marine tourism industry where the existence of commercial fishing is part of the visitors’ tourism experience. In this paper in-depth interviews with local representatives for the tourism sector are combined with

Cleaning and tailoring the Pt3Sn(111) surface for surface experiments

The cleaning process of the bimetallic Pt3Sn(111) surface has been studied by means of low-energy electron microscopy (LEEM), microspot low-energy electron diffraction (μ-LEED), and X-ray photoemission electron microscopy (XPEEM). Different cleaning procedures, performed under ultra-high vacuum conditions (UHV), including sputtering with argon ions and repeated cycles of annealing up to 1500 K wer

Apathy in Alzheimer's disease : A neurocircuitry based perspective

In addition to memory deficits and other cognitive disturbances, patients with Alzheimer's disease (AD) experience neuropsychiatric symptoms, notably apathy, which is a state of impaired motivation observed by deficits in goal directed behavior. Apathy is a multifaceted neuropsychiatric condition and appears to be a prognostic indicator, correlating with the progression of AD. Strikingly, recent s

Refugee migration from Ukraine to other parts of Europe: Challenges to the housing-integration intersection at the city level

In the context of the massive refugee influx from Ukraine to its European neighbouring states over the last months, this update reflects on the experiences of two international exchanges led by HOUSE-IN: a JPI Urban Europe-funded project that deals with challenges at the housing-integration nexus. The exchanges revealed the impacts of this forced migration at the intersection of housing and integr

Comparison of membrane fouling during ultrafiltration with adsorption studied by quartz crystal microbalance with dissipation monitoring (QCM-D)

Even though membrane technology is used in numerous industrial applications, membrane fouling is still a major challenge. Valuable information on the formation kinetics and structure of the fouling layer can be obtained by in situ real-time monitoring. Quartz crystal microbalance with dissipation monitoring (QCM-D) enables the study of adsorptive fouling in situ on a model membrane. However, so fa

Synchrotron-based near ambient-pressure X-ray photoelectron spectroscopy and electrochemical studies of passivation behavior of N- and V-containing martensitic stainless steel

Passivation behavior of a N- and V-containing martensite stainless steel was studied by synchrotron-based near ambient-pressure X-ray photoelectron spectroscopy, electrochemical analyses, and thermodynamic calculation. The passive film consists of Cr3+, Fe(2, 3)+, and V(2, 3, 4)+ oxides as inner layer, and Cr3+ and Fe3+ hydroxides as outer layer. Austenitization at 1080 oC (rather than 1010 oC) an

Pregnenolone for the treatment of L-DOPA-induced dyskinesia in Parkinson's disease

Growing preclinical and clinical evidence highlights neurosteroid pathway imbalances in Parkinson's Disease (PD) and L-DOPA-induced dyskinesias (LIDs). We recently reported that 5α-reductase (5AR) inhibitors dampen dyskinesias in parkinsonian rats; however, unraveling which specific neurosteroid mediates this effect is critical to optimize a targeted therapy. Among the 5AR-related neurosteroids, s

Functional genome annotation and transcriptome analysis of Pseudozyma hubeiensis BOT-O, an oleaginous yeast that utilizes glucose and xylose at equal rates

Pseudozyma hubeiensis is a basidiomycete yeast that has the highly desirable traits for lignocellulose valorisation of being equally efficient at utilization of glucose and xylose, and capable of their co-utilization. The species has previously mainly been studied for its capacity to produce secreted biosurfactants in the form of mannosylerythritol lipids, but it is also an oleaginous species capa

Leaving Their Mark: Using Danish Student Grade Lists to Construct a More Detailed Measure of Historical Human Capital

We provide a brief overview of the educational history of Denmark and document archival and printed sources covering the development of primary, secondary, and tertiary education. In particular, we focus on student grade lists, which are available for individuals at all levels of education from the early Nineteenth century until well into the Twentieth century. We suggest that these can be used to

Harmonious relations: quality transmission among composers in the very long run

Most creative professionals develop and refine their talents by learning from others. In most empirical settings, estimating how this learning process fosters quality is challenging. This paper explores the transmission of quality among music composers over more than seven centuries. How does a composer’s quality influence the quality of the composers they teach? Using a unique dataset of 17,433 c

Using machine learning to select variables in data envelopment analysis : Simulations and application using electricity distribution data

Agencies that regulate electricity providers often apply nonparametric data envelopment analysis (DEA) to assess the relative efficiency of each firm. The reliability and validity of DEA are contingent upon selecting relevant input variables. In the era of big (wide) data, the assumptions of traditional variable selection techniques are often violated due to challenges related to high-dimensional

P90 ribosomal S6 kinases : A bona fide target for novel targeted anticancer therapies?

The 90 kDa ribosomal S6 kinase (RSK) family of proteins is a group of highly conserved Ser/Thr kinases. They are downstream effectors of the Ras/ERK/MAPK signaling cascade. ERK1/2 activation directly results in the phosphorylation of RSKs, which further, through interaction with a variety of different downstream substrates, activate various signaling events. In this context, they have been shown t

Unreported incidental pulmonary embolism in patients with cancer : Radiologic natural history and risk of recurrent venous thromboembolism and death

Purpose: To assess the risk of recurrent venous thromboembolism (VTE) and death in patients with unreported cancer-associated incidental pulmonary embolism (iPE). Materials and methods: Matched cohort study on cancer patients with a CT study including the chest between 2014-01-01 and 2019-06-30. Studies were reviewed for unreported iPE, and cases were matched with controls without iPE. Cases and c

Rapid formation of new migration route and breeding area by Arctic geese

Many Arctic-breeding animals are at risk from local extirpation associated with habitat constriction and alterations in phenology in their Arctic environment as a result of rapid global warming.1 Migratory species face additional increasing anthropogenic pressures along their migratory routes such as habitat destruction, droughts, creation of barriers, and overexploitation.2,3 Such species can onl