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On the Generalization of the GMS Evolutionary Model
We study a generalization of the evolution model proposed by Guiol, Machado and Schinazi [4]. In our model, at each moment of time a random number of species is either born or removed from the system; the species to be removed are those with the lower fitnesses, fitnesses being some numbers in [0, 1]. We show that under appropriate conditions, a set of species approaches (in some sense) a sample f
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The aim of our work was to calculate basic mathematical characteristics of payment functional, such as mathematical expectation, variation and expected risk in discrete and continuous market models. In our paper we present a model of financial market in which the entire time interval in the continuous model is divided into steps with exponential distribution, and in the discrete model into steps o
Effects of linear amphiphilicity on membrane interactions of C-terminal thrombin peptides
Effects of linear amphiphilicity on membrane interactions of antimicrobial peptides were investigated by ellipsometry, dual polarization interferometry, fluorescence spectroscopy, light scattering, and circular dichroism. In doing so, the thrombin-derived GKY25 (GKYGFYTHVFRLKKWIQKVIDQFGE) was compared to WFF25 (WFFFYYLIIGGGVVTHQQRKKKKDE) of identical composition, but with amino acids sorted accord
Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets
The molecular basis of type 2 diabetes predisposition at most established susceptibility loci remains poorly understood. KCNQ1 maps within the 11p15.5 imprinted domain, a region with an established role in congenital growth phenotypes. Variants intronic to KCNQ1 influence diabetes susceptibility when maternally inherited. By use of quantitative PCR and pyrosequencing of human adult islet and fetal
Semi-empirical atomistic study of point defect properties in BCC transition metals
We have constructed a set of embedded atom method (EAM) potentials for Fe, Ta, W and V and used them in order to study point defect properties. The parametrizations of the potentials ensure that the third order elastic constants are continuous and they have been fitted to the cohesive energies, the lattice constants, the unrelaxed vacancy formation energies and the second order elastic constants.
Evaluation of Level of Confidence and Optimization of Roll-back Recovery with Checkpointing for Real-Time Systems
Increasing soft error rates for semiconductor devices manufactured in later technologies enforce the usage of fault tolerant techniques such as Roll-back Recovery with Checkpointing (RRC). As RRC introduces time overhead that increases the completion (execution) time, time constraints (deadlines) might be violated. This is a drawback for a class of computer systems where the correct operation is d
Endoscopic assessment and grading of Barrett's esophagus using magnification endoscopy and narrow band imaging: Impact of structured learning and experience on the accuracy of the Amsterdam classification system
Objective. Several classification systems have been launched to characterize Barrett's esophagus (BE) mucosa using magnification endoscopy with narrow band imaging (ME-NBI). The good accuracy and interobserver agreement described in the early reports were not reproduced subsequently. Recently, we reported somewhat higher accuracy of the classification developed by the Amsterdam group. The critical
Arterial dysfunction but maintained systemic blood pressure in cavin-1-deficient mice.
Caveolae are omega-shaped plasma membrane micro-domains that are abundant in cells of the vascular system. Formation of caveolae depends on caveolin-1 and cavin-1 and lack of either protein leads to loss of caveolae. Mice with caveolin-1 deficiency have dysfunctional blood vessels, but whether absence of cavin-1 similarly leads to vascular dysfunction is not known. Here we addressed this hypothesi
Gut Manifestations in an Experimental Model of Multiple Sclerosis
Multiple sclerosis (MS) is an immune-mediated demyelinating and neurodegenerative disease of the central nervous system (CNS). Neuroinflammatory processes in MS are believed to lead to damage and leakage in the blood-brain barrier that protects the CNS and regulates the trafficking of soluble mediators and leukocytes. MS is thought to be triggered in genetically susceptible individuals following e
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BACQUIN, MARI, Theseus de Cologne, édition partielle d’une chanson de geste du XIVe siècle. Études romanes de Lund, 81, 355 pages. Written in French. Monograph. Theseus de Cologne is a French romance from the fourteenth century written by an anonymous author. This voluminous work contains more than 26,000 lines. The text of the romance is preserved in three manuscripts from the fifteenth century,
Two-particle Aharonov-Bohm effect in electronic interferometers
We review recent theoretical investigations on the two-particle Aharonov-Bohm effect and its relation to entanglement production and detection. The difficulties of the entanglement detection due to dephasing and finite temperature are discussed regarding a recent experimental realization of a two-particle Aharonov-Bohm interferometer [15]. We also discuss a theoretical proposal for a two-particle
Phase transition pathways for the production of 100 nm oil-in-water emulsions
Oil/water emulsions can be produced through phase inversion, by adding water to a reverse water/oil microemulsion. According to small angle neutron scattering experiments and visual observations performed during phase inversion, the stages of this process are as follows: (i) upon water addition, the microemulsion gives way to a highly swollen lamellar phase; (ii) the transient lamellar phase break
ELUCIDATING REGULATORY NETWORKS PROMOTING B-CELL DEVELOPMENT
Popular Abstract in Swedish Vårt blod består av flera olika specialiserade typer av celler. Dessa utför allt från transport av syre (röda blodkroppar) och sårläkning (blodplättar) till att utgöra vårt immunsystem (vita blodkroppar). Vårt immunförsvar kommer ständigt i kontakt med virus, bakterier och sjuka celler som måste kännas igen och bekämpas. Därför finns det ett kontinuerligt behov av att bB-cells are an essential part of our adaptive immune system. A network of transcription factors together with external signals facilitate the gradual developmental progression from progenitor cells towards the B-cell fate. Several key factors participating in this network have been identified. Among these are the transcription factors E2A, HEB, EBF1 and FOXO1 as well as the IL7 signaling cascade.
Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens.
Malaria is a major global cause of deaths and a vaccine is urgently needed.
Decreased expression of RNA-binding motif protein 3 correlates with tumour progression and poor prognosis in urothelial bladder cancer
BACKGROUND: Low nuclear expression of the RNA-binding motif protein 3 (RBM3) has previously been found to be associated with poor prognosis in several cancer forms e.g. breast, ovarian, colorectal, prostate cancer and malignant melanoma. The aim of this study was to examine the prognostic impact of RBM3 expression in urinary bladder cancer.METHODS: Immunohistochemical RBM3 expression was examined
Clause combining in Semitic : The circumstantial clause and beyond
The volume presents the results of an international project carried out in cooperation between the Uppsala University, the Hebrew University in Jerusalem, Lund University and the University of Gothenburg. The questions put forward in the project were: How is hypotaxis marked in Semitic, other than by conjunctions? How does this affect the organization of texts? More specifically, what constitutes
Switched on to cancer
Scandinavian journal of modern greek studies
Properties of self-assembled Bi nanolines on InAs(100) studied by core-level and valence-band photoemission, and first-principles calculations
We have studied self-assembled bismuth (Bi) nanolines on the Bi-terminated InAs(100) surface by core-level and valence-band photoelectron spectroscopy, and ab initio first-principles calculations. A structural model for this intriguing surface is suggested based on the comparison of the measured and calculated core-level shifts. Also, the atomic origins for the core-level shifts are proposed based