General Circulation and Earth System Models are the most advanced tools for investigating climate responses to future scenarios of greenhouse gas emissions, playing the role of projecting the climate throughout the century. Nevertheless, climate projections are model-dependent and may show systematic biases, requiring a bias correction for any further application. Here, we provide a dataset based

Artificial intelligence (AI) has been used to develop drug sensitivity prediction models, raising the opportunity of using it for personalized cancer medicine. This chapter describes recent advancements in drug response prediction methods using machine learning algorithms. Pharmacogenomic datasets come with different types of biological data including genetic mutations, gene expression, copy numbe

Digitalisation has developed over half a century and is one of the global trends defining society of today and future. Digitalisation is envisioned to help water utilities to become: i) community orientated and digitally integrated with customers and society; ii) digitally transformed end-to-end throughout the value-chain and interconnected between business units; iii) predictive & proactive,

Material interfaces can occur at different material length scales. Understanding the properties and the behaviour of interfaces is of utmost importance because interfaces can significantly influence the effective constitutive response of the material under consideration. Based on the fundamentals of electro-mechanically coupled cohesive zone formulations for electrical conductors and on the associ

Hormone secretion from pancreatic islets is essential for glucose homeostasis and loss or dysfunction of islet cells is a hallmark of type 2 diabetes. Maf transcription factors are critical for establishing and maintaining adult endocrine cell function. However, during pancreas development, MafB is not only expressed in insulin- and glucagon-producing cells, but also Neurog3+ endocrine progenitor

This concluding article assesses the past decade of international scholarship on the European Union (EU) and normative power as represented by the contributions to the special issue. It argues that the normative power approach (NPA) makes it possible to explain, understand and judge the EU in global politics by rethinking the nature of power and actorness in a globalizing, multilateralizing and mu

Amyloid fibrils are associated with a number of different neurodegenerative diseases. Detailed knowledge of the fibril structure will be of importance in the search of therapy and may guide experiments to understand amyloid formation. In this paper we investigate the morphology of α-synuclein amyloid fibrils, associated with Parkinson’s disease, formed under different conditions. In particular, we

I argue that there can be value relations without individual values to support them. The fact that an item is better than another item does not have to be explained by reference to the values of the individual items. Instead, value relations can be grounded directly and exhaustively in descriptive facts about their relata. I show that my suggestion fits well with plausible perspectives on the natu

Abstract in DanishMan har ikke kunne undgå at høre om the Belt and Road Initiative (BRI), One Belt, One Road, eller Den Nye Silkevej, som et af Xi Jinpings og Kinas vigtigste projekter bliver kaldt.Sammen med Tabita Rosendahl, Sinolog og PhD-studerende ved Lund Universitet, der forsker i netop BRI, dykker vi ned i Kinas Belt and Road Initiative.Hør om baggrunden for BRi, hvorfor det er vigtigt for

Widespread contamination of ecosystems with pesticides threatens non-target organisms. However, the extent to which life-history traits affect pesticide exposure and resulting risk in different landscape contexts remains poorly understood. We address this for bees across an agricultural land-use gradient based on pesticide assays of pollen and nectar collected by Apis mellifera, Bombus terrestris

In 1827, an Indian juggler named Mooty Madua Samme converted to Christianity in Stockholm, Sweden. This historical event got much attention in the press at the time – as did his succeeding marriage to a Swedish woman named Erica – and was celebrated as a victory for the Evangelical Lutheran faith. Later, in the 1840s, a narrative depicting the event spread via a travelogue by Xavier Marmier, which

Background: Hypertension is the leading modifiable risk factor for cerebral small vessel diseases (SVDs). Yet, it is unknown whether antihypertensive drug classes differentially affect microvascular function in SVDs. Aims: To test whether amlodipine has a beneficial effect on microvascular function when compared to either losartan or atenolol, and whether losartan has a beneficial effect when comp

Syfte: Syftet med vår studie var att undersöka hur personer med afasi upplever sin kommunikation och livskvalitet och om upplevelsen har ett samband med svårighetsgrad av stroke, svårighetsgrad av afasi samt kognitiv förmåga. Metod: I studien ingick 30 deltagare som fått afasi till följd av en ischemisk stroke. Tre månader efter insjuknandet genomförde deltagarna Comprehensive Aphasia Test (CAT).Purpose: The aim of the present study was to investigate how people with aphasia experience their communication and quality of life and whether the experience is related to degree of stroke, degree of aphasia and cognitive ability. Method: The study included 30 participants who acquired aphasia as a result of an ischemic stroke. Three months post stroke, participants completed the Comprehensive Ap

Syfte: Studien syftar till att kartlägga hur erfarna logopeder i konsensus perceptuellt bedömer transkvinnors röster. Ett vidare syfte är kartlägga om logopedernas perceptuella konsensusbedömning av parametern maskulin respektive feminin och parametern röstansträngning korrelerar med transkvinnornas självskattning av samma parametrar. Metod: Undersökningen är en deskriptiv studie som kombinerar kPurpose: The following study attempts to map how experienced speech-language pathologists perceptually evaluate trans women’s voices in consensus. A further purpose is to compare perceptual evaluations of speech-language pathologists (SLP’s), to examine any correlation to trans women’s self-evaluation of the same parameters. Method: This descriptive study entails quantitative as well as qualitat

Multiple scales measuring a customer's, or consumer's, engagement (CE) with a brand or specific brand elements (e.g., advertising/social media content) have been proposed in the literature, offering researchers different options to gauge CE. However, the myriad proposed operationalizations can yield confusion among scholars regarding how to best capture CE, exposing a growing issue for CE research