Many cell functions rely on the ability of microtubules to self-organize as complex networks. In plants, cortical microtubules are essential to determine cell shape as they guide the deposition of cellulose microfibrils, and thus control mechanical anisotropy in the cell wall. Here we analyze how, in turn, cell shape may influence microtubule behavior. Using a computational model of microtubules e

The plant shoot apical meristem holds a stem cell niche from which all aerial organs originate. Using a computational approach we show that a mixture of monomers and heterodimers of the transcription factors WUSCHEL and HAIRY MERISTEM is sufficient to pattern the stem cell niche, and predict that immobile heterodimers form a regulatory ‘pocket’ surrounding the stem cells. The model achieves to rep

Processes in individual and mass production are governed by certain principles which need to be taken into account as early as the conceptual design phase. A comprehensive analysis of processes in tool production has shown that production also needs to be considered in remodeling or the introduction ofconcurrent engineering. The paper discusses the principles of the manufacturing process which aff

Many small companies ask themselves how and when to begin participating in the information revolution, and what changes this may bring to their business operation. Five typical models of product data integration were designed to help users to create a comprehensive view of the problems of technical information systems in companies. It was found that setting up an information system is a dynamic pr

The management system presented in the paper allows the generation and control of documentation flow throughout the whole manufacturing process, from all design levels to manufacturing. Using the method of quality assurance, a useful management system has been developed that covers cooperative work between different departments, clear responsibilities, the description of procedures for documentati

When re-engineering a company's information system, one must have a thorough knowledge of the work process. In this article, the methodology of analysis of information creation and information flow is presented. The most important requirements are identified, and concrete solutions are given for the creation of an appropriate information system. As an illustration, a virtual toolmaking factory is

A rich understanding of the productivity, carbon and nutrient cycling of terrestrial ecosystems is essential in the context of understanding, modelling and managing the future response of the biosphere to global change. This need is particularly acute in tropical ecosystems, home to over 60% of global terrestrial productivity, over half of planetary biodiversity, and hotspots of anthropogenic pres

The paper presents application of lean engineering methods at design process re-engineering. Lean principles are harder to implement in an one-of-a-kind production environment rather than in an environment of a serial production, where there are almost no changes during production process. There are considerable differences in value-added activities that characterize lean production on one hand an

Application of concurrent engineering (CE) to product development process (PDP) has to consider the type of production (individual, serial, mass), product complexity and level of design: original, innovative, variation and adaptive. Systematic analyses of product development processes, workflows, data and project management, in various companies, has shown that specific criteria have to be fulfill

Aircraft Maintenance and Repair Organizations (MRO) have to be competitive and attractive for the existing and new customers. Aircraft ground time at the MRO has to be as short as possible as well as cost efficient without reducing the quality of the accomplished work. Application of lean methods into aircraft maintenance processes means continuous improvement process and elimination of non-value-

We present a program allowing for the construction of a heavy ion Monte Carlo event using a general purpose proton–proton event generator of the users’ choice to deliver sub–collisions. In this heavy ion event, one or more jets can be added, again using a jet calculation of the users’ choice, allowing for more realistic simulation studies of jets in a heavy ion background.

Vacuum cleaner motor is an air cooled single-phase induction motor with impeller. Its compact design can result in more than 2 kW of input power per 1 kg of mass. It can operate only if an air flow is cooling the motor; otherwise it is overheated and destroyed. A large production volume of a vacuum cleaner motor classifies it as a mass production product. In the past its development has been mostl

Tools and methods are an important part of product development process. Advantages of different methods are growing with product novelty and complexity. Moderation of product development team meeting is a challenge at face to face meetings. Moderation has to be conducted with additional care at spatially distributed or virtual teams. The workshops or meetings related to different tools and methods

The modelling of biological systems often consists into differential equation models that need to be fitted to experimental data. During this complex process, the practical experience of the biologist and the theoretical abstraction of the modeller require back-and-forth refinements of the model, design of new experiments and inclusion of more data-points into the fitting procedure. Available opti

Historical commons represent self-governed governance regimes that regulate the use and management of natural and man-made shared resources. Despite growing scientific interests, analyses of commons evolution and temporal dynamics are rare and drivers of change (birth, adaptation, dissolution) remain obscure. We apply an interdisciplinary approach and address these issues from an eco-evolutionary

Scholarly journals are often blamed for a gender gap in publication rates, but it is unclear whether peer review and editorial processes contribute to it. This article examines gender bias in peer review with data for 145 journals in various fields of research, including about 1.7 million authors and 740,000 referees. We reconstructed three possible sources of bias, i.e., the editorial selection o