Using direct cell reprogramming to induce functional plasmacytoid dendritic cells from fibroblasts Direct cell reprogramming is a technique used to generate differentiated cells of one lineage from somatic cells of another. This concept has been used to explore the diversity and function of numerous cell types. Plasmacytoid dendritic cells (pDCs) are a subset of dendritic cells specialized at pro

With this research we aim to understand the dynamics of consumers' use of cancel culture as a resource for their identity construction online. Theories included were surrounding framing, morality, consumers as moral protagonists, purity and dirt as well as distaste and symbolic violence. These theories were selected to aid with the analysis of the empirical material and to add new insight to t

Despite being their closest evolutionary relatives, chimpanzees have a substantially different brain compared to humans: Homo sapiens display larger and more complex forebrains, although the protein-coding genes between the two species are basically unchanged. Therefore, differences in the transcriptome and in regulatory networks must be further investigated to better understand the dissimilaritie

The 83 million year old family tree of burnet moths To classify the living world around them, early on humans started naming plants and animals in order to distinguish food from non-food, predator from prey, etc. In 1800s a practice of a more formal way of classifying the living world was started, in which using Latin names made the classification universal. The unique appearances were used to di

Human-wildlife conflicts threaten the existence of many species worldwide. Large carnivores are often involved in such conflicts due to their diets and expansive home ranges. In Finland, wolf (Canis lupus) is one of such conflict-prone species. The wolf conflict is a multifaceted issue stemming for instance from fears, damages to domestic animals, competition for game and opposition of EU wildlife

The purpose of this paper is to investigate what motivates the recidivism discrepancy between populations with: severe psychiatric disorder and non-severe psychiatric disorder. The aim is to introduce an argument for biopsychosocial influences as underlying an individual’s propensity to act, using Luhmannian systems theory. By making use of current research on social and neurological risk factors,

I denna magisteruppsats undersöks hur dialekten i romanen Machandel av Regina Scheer kan översättas till svenska på ett källtexttroget sätt. Inom ramen för magisterarbetet har utdrag ur romanen översatts, och i uppsatsen analyseras denna översättning. Dialektens centrala roll i verket presenteras i en källtextanalys, följd av ett resonerande kapitel om utgångspunkterna för översättningen. Riktlinj

The overall purpose of the thesis is to gather deeper insights into the redesign of management control systems (MCSs) following a shift in value emphasis in family-owned firms by exploring the different dynamics of the family business system (FBS). Furthermore, the research has aimed to find an answer to how a shift from family management to external management influences the value emphasis, and h

Barn som bevittnat våld i nära relationer är en utsatt grupp vars behov ofta förbises(Socialstyrelsen 2019). Såväl svensk som internationell forskning på området visar att denna form av utsatthet får allvarliga konsekvenser på både lång och kort sikt. Samtidigt indikerar andra studier på kunskapsluckor och brister i arbetet med barn som bevittnat våld vilket resulterar i att dessa barn inte får de

Emerging infectious diseases (EID) continue to threaten the persistence of wildlife populations. The standing genetic variation of a population can affect its ability to adapt to environmental changes like EID. Levels of variation at immune genes, such as toll-like receptor genes (TLR) of the innate immune system, are particularly relevant. The current study explores the role of demographic histor

Fractal curves are self similar objects, most of which have the property of being nowhere differentiable. The foundations of fractal curves are in the study of continuous functions with no points of differentiability. In this thesis, the continuity and nowhere differentiability of the Weierstrass function will be proved by using an auxiliary function and mostly elementary tools from Fourier analys

En viktig del av finansmarknaden är kreditmarknaden, där företag, banker och investerare köper och säljer olika former av skuldbrev. Ett ofta använt verktyg på kreditmarknaden är den så kallade avkastningskurvan. Avkastningskurvan beskriver räntan på en samling liknande obligationer som en funktion av löptiden. Den är viktig för att prissätta instrumenten som handlas på kreditmarkaden, men kan äveThe yield curve of a collection of debt contracts describes the yield of the debt contract as a function of the length-to-maturity of the contract. It turns out that these yield curves provide useful insight about the economy as a whole and can, for example, be used to predict short-term economic downturns. Therefore, it is of utmost importance that financial analysts and decision-makers are able

Berlin Dialect in Swedish? : How Berlin Dialect is Represented in the Swedish Translation of Berlin Alexanderplatz Alfred Döblin’s modern novel Berlin Alexanderplatz, first published in 1929, is strongly characterized by the Berlin dialect and colloquial speech. The first complete Swedish translation of this renown work was conducted by Ulrika Wallenström in 1978. This thesis investigates to what

This thesis analyses the relationship between sustainability transformations and grassroots movements in Monteverde, Costa Rica. The focus is toward understanding the influence of community-based initiatives on transformations that have sustainability as a goal, due to their potential for shaping society and addressing challenges such as climate change. The study also examines the emergence and de

Introduction: Narasin is a feed additive for animals to treat the parasitic disease Coccidiosis. The antibiotic is deadly to humans when consumed in large amounts. Studies has shown that Narasin can transfer on Vancomycin resistant E. Faecium (VRE). Vancomycin is an antibiotic used to treat bacterial infections in humans. The resistance could be passed on to humans from the chicken and contribute

Celldelning -Livets process De allra flesta levande celler delar sig. Multicellulära organismer gör det för att bygga upp vävnader eller för att förnya och ersätta skadade celler. Encelliga organismer delar sig för att föröka sig och hålla sin population levande. För att en bakterie ska överleva och föra sina gener vidare måste den dela på sig. Detta sker via en process som kallas binär fissio

Seawater intrusion has been aggravated due to anthropogenic reasons, such as sea level rise and over abstraction of groundwater, which is spoiling the groundwater sustainability. This study focused on a negative hydraulic barrier using a barrier well as a countermeasure. Two lab-scale experiments and a numerical analysis with a 2-D solute transport model were conducted to examine an optimal locati

Conductance was calculated for trapezoidal nanowires with different forms and strengths of imperfection using kwant, a quantum transport software package that uses a tight-binding model. In this thesis it is found that increasing magnitudes of different imperfections such as surface charge and roughness roughen conductance steps, introduce resonances, and lower conductance overall with different c

Introduction: This study was performed to optimize extraction of lead, copper and zinc from seaweed using pressurized hot water, to investigate the selectivity and extractability of the extraction. Background: Pressurized hot water extraction is an environmentally sustainable method in comparison to more common extraction methods, such as distillation or solvent extraction, used with plant mater