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Tumour growth after portal vein embolization with pre-procedural chemotherapy for colorectal liver metastases.

For resection of colorectal cancer (CRC) liver metastases, pre-operative portal vein embolization (PVE) is used to increase the size of the future liver remnant (FLR) prior to advanced liver resection when indicated. PVE is speculated to cause tumour progression, but only a limited number of studies have analysed tumour growth after PVE in the context of pre-procedural chemotherapy, which was the

Factors governing human fear of brown bear and wolf

This article analyzes people's subjectively experienced fear in areas with presence of brown bear or wolf. Departing from the Human-Environment Interaction Model (Küller, R. 1991) a hypothetical model of environmental and individual antecedents of fear was tested using structural equation modeling of survey data (n = 391). In the model of fear of brown bear, the main predictor was the appraisal of

Self-doubters, strugglers, storytellers, surfers and others: Images of self-identities in organization studies

This article provides an overview of the key images of identity in organizations found in the research literature. Image refers to the overall idea or conceptualization, capturing how researchers relate to - and shape - a phenomenon. Seven images are suggested: self-doubters, strugglers, surfers, storytellers, strategists, stencils and soldiers. These refer to how the individual is metaphorically

Transcriptional Regulation in Ebola Virus: Effects of Gene Border Structure and Regulatory Elements on Gene Expression and Polymerase Scanning Behavior.

The highly pathogenic Ebola virus (EBOV) has a nonsegmented negative-strand (NNS) RNA genome containing seven genes. The viral genes either are separated by intergenic regions (IRs) of variable length or overlap. The structure of the EBOV gene overlaps is conserved throughout all filovirus genomes and is distinct from that of the overlaps found in other NNS RNA viruses. Here, we analyzed how diver

Phosphorylation of the activation loop tyrosine 823 in c-Kit is crucial for cell survival and proliferation.

The receptor tyrosine kinase c-Kit, also known as the stem cell factor receptor, plays a key role in several developmental processes. Activating mutations in c-Kit lead to alteration of these cellular processes and have been implicated in many human cancers such as gastrointestinal stromal tumors (GISTs), acute myeloid leukemia (AML), testicular seminomas and mastocytosis. Regulation of the cataly

Detection of radioactive fragments in patients after radiological or nuclear emergencies using computed tomography and digital radiography.

A comparison has been carried out between standard-dose computed tomography, non-diagnostic computed tomography and digital radiography with respect to their suitability for detecting radioactive fragments associated with nuclear or radiological events such as debris from radiological dispersal devices. The purpose was to investigate if radiographic imaging is justified for the detection and local

Physicochemical properties of different thickeners used in infant foods and their relationship with mineral availability during in vitro digestion process

Locust bean gum (LBG) and modified starches are commonly used as thickeners in food products for infants. However, there is no consensus on their possible effects on infant nutrition, especially on mineral availability. The aim of the present work was to characterize the effect of LBG, cross-linked, hydroxypropylated maize starch (Mhdp) and pre-gelatinized rice starch (gRS) on Ca, Fe and Zn availa

Vicariance divergence and gene flow among islet populations of an endemic lizard.

Allopatry and allopatric speciation can arise through two different mechanisms: vicariance or colonization through dispersal. Distinguishing between these different allopatric mechanisms is difficult and one of the major challenges in biogeographical research. Here, we address whether allopatric isolation in an endemic island lizard is the result of vicariance or dispersal. We estimated the amount

Recent trends and drivers of regional sources and sinks of carbon dioxide

The land and ocean absorb on average just over half of the anthropogenic emissions of carbon dioxide (CO2) every year. These CO2 "sinks" are modulated by climate change and variability. Here we use a suite of nine dynamic global vegetation models (DGVMs) and four ocean biogeochemical general circulation models (OBGCMs) to estimate trends driven by global and regional climate and atmospheric CO2 in

Sex effects on short-term complications after hip fracture: a prospective cohort study

Objectives: To evaluate potential sex differences and other factors associated with complications within 4 months after a hip fracture. Methods: A total of 1,915 patients. 65 years (480 men) with hip fracture were consecutively included in a prospective multicenter cohort study. A review of medical records and patient interviews according to a study protocol based on the Standardized Audit of Hip

Filtered Stochastic Shadow Mapping Using a Layered Approach

Given a stochastic shadow map rendered with motion blur, our goal is to render an image from the eye with motion-blurred shadows with as little noise as possible. We use a layered approach in the shadow map and reproject samples along the average motion vector, and then perform lookups in this representation. Our results include substantially improved shadow quality compared to previous work and a

Visibility conditions and diel period affect small-scale spatio-temporal behaviour of pike Esox lucius in the absence of prey and conspecifics

Pike Esox lucius in the absence of prey and conspecifics were shown to have the highest habitat-change activity during dusk and to decrease preference for complex habitats in turbid water. As the behaviours indicate routine responses in the absence of behavioural interactions, E. lucius spatio-temporal distributions should be directly affected and thereby more easily assessed and avoided by prey,

Cyclic and linear monoterpenes in phospholipid membranes: Phase behavior, bilayer structure, and molecular dynamics.

Monoterpenes are abundant in essential oil extracted from plants. These relatively small and hydrophobic molecules have shown many important biological fucntions, including antimicrobial activity and membrane penetration enhancement. The interaction between the monoterpenes and lipid bilayers is considered important to the understanding of the biological functions of monoterpenes. In this study we

The last termination in the central South Atlantic

Lake sediments and peat deposits from two basins on Nightingale Island (37 degrees S), in the Tristan da Cunha archipelago, South Atlantic, have been analyzed. The studies were focused on the time period 16.2-10.0 cal ka BP, determined by 36 C-14 dates from the two sequences. A wide variety of proxies were used, including pollen and diatom analyzes, biogenic silica content, C and N analyzes, stabl

BENCHOP—The BENCHmarking project in Option Pricing

The aim of the BENCHOP project is to provide the finance community with a common suite of benchmark problems for option pricing. We provide a detailed description of the six benchmark problems together with methods to compute reference solutions. We have implemented seventeen different numerical methods for these problems, and compare their relative performance. All implementations are available o

The age and genomic integrity of neurons after cortical stroke in humans.

It has been unclear whether ischemic stroke induces neurogenesis or neuronal DNA rearrangements in the human neocortex. Using immunohistochemistry; transcriptome, genome and ploidy analyses; and determination of nuclear bomb test-derived (14)C concentration in neuronal DNA, we found neither to be the case. A large proportion of cortical neurons displayed DNA fragmentation and DNA repair a short ti

Transmission of infrared and visible wavelengths through energy-saving glass due to etching of frequency-selective surfaces

The transmission of infrared (IR) and visible frequencies through modern energy-saving glass, due to etching of bandpass frequency-selective surfaces (FSSs), is analysed. Energy-saving glass panels employ a very thin layer of metallic oxide on one side of the ordinary glass. Due to the presence of this layer, IR waves are attenuated whereas visible wavelengths can pass through, providing good see-

Nipponoparmelia perplicata sp. nov. (Parmeliaceae, Ascomycota) from eastern Asia

A new species, Nipponoparmelia perplicata described from Korea and Russia, is segregated from N. laevior, from which it differs in having shorter and wider lobes that characteristically turn down towards the margins. The pseudocyphellae are inconspicuous, positioned along the lobe margins or on the underside. An improved description of N. pseudolaevior is presented, including new data on isidia wi