The standard treatment of glioblastoma, an aggressive brain tumour, includes radiotherapy combined with temozolomide. Based on a randomised trial, showing five months increased survival, TTF has been introduced in the management of patients with good performance status. Data from the Swedish national quality registry for CNS tumours have been analysed for TTF usage. The results demonstrate that 65

Wood-water interactions are central to the utilization of wood in our society since water affects many important characteristics of wood. This topic has been investigated for more than a century, but new knowledge continues to be generated as a result of improved experimental and computational methods. This review summarizes our current understanding of the fundamentals of water in wood and highli

BACKGROUND: SARS-CoV-2 has been shown to predominantly infect the airways and the respiratory tract and too often have an unpredictable and different pathologic pattern compared to other respiratory diseases. Current clinical diagnostical tools in pulmonary medicine expose patients to harmful radiation, are too unspecific or even invasive. Proteomic analysis of exhaled breath particles (EBPs) in c

Balancing personal desire and social expectations, fathers who seek greater gender equality in the family today often face stereotypes at work and in society. Reflections from a collection of interviews

The impacts of adverse weather conditions on railway infrastructure can result in delays and cancellations across the railway network and increased maintenance costs. The frequency and severity of extreme weather events are expected to rise due to climate change, making railways more vulnerable. This study aims to gain a better understanding of weather-related infrastructure failures (specifically

The accurate estimation of soil carbon (C) pool and fluxes is a prerequisite to better understand the terrestrial C feedback to climate change. However, recent studies showed considerable uncertainties in soil C estimates. To provide a reliable C estimate in the grasslands of the Qinghai-Tibet Plateau (QTP), we calibrated key parameters in a process-based ecosystem model (the CENTURY model) throug

This thesis explores the role played by norms and social actors in establishing the acceptability and the purported validity of leadership measures. Taking an interpretivist and critical approach, I examine the subjective and normative side of supposedly objective quantitative assessment tools.Through observations, interviews, and document analysis I uncover the normative agendas and social contex

I detta kapitel ställs frågor om betydelsen av mellanmänskliga möten inom vården utifrån ett patientperspektiv. Närmare bestämt hur kvinnor med bröstcancer upplevt att de fått balansera den medicinska vårdens effektivitet mot ett delvis uteblivet känslomässigt och personligt bemötande. Det kan beskrivas som ett känsloarbete där de medicinska villkoren väger över så att de egna känslorna inte får d

Moving from a fossil dependent to a fossil free economy requires increased energy production from renewable resources. This thesis discusses the utilization of agricultural waste streams, such as straw and manure, for biogas production. The first part of the research presented focuses on pretreatment of straw with the aim to reduce the handling issues concerning straw and improve the degradation o

I det här kapitlet beskriver och diskuterar vi hälso- och sjukvårdskuratorns roll i ett historiskt såväl som nutida perspektiv. Frågor i fokus handlar om hur den nyligen införda yrkeslegitimationen för kuratorer inom hälso- och sjukvården påverkar arbetssituationen avseende autonomi, jurisdiktion och samverkan med andra yrkesgrupper. Förändras yrkets legitimitet i organisationen? Vilka möjligheter

INTRODUCTION: Immune cells in the tumour microenvironment are associated with prognosis and response to therapy. We aimed to comprehensively characterise the spatial immune phenotypes in the mutational and clinicopathological background of non-small cell lung cancer (NSCLC).METHODS: We established a multiplexed fluorescence imaging pipeline to spatially quantify 13 immune cell subsets in 359 NSCLC