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RIFM fragrance ingredient safety assessment Dimethyl succinate, CAS Registry Number 106-65-0
Theoretical study of the effect of π+-π+ association in imidazolium ionic liquids at charged interfaces
We develop an extended classical density-functional theory to describe clustering of imidazolium-based cations into linear chains, driven by π-π stacking. We find that the associating system displays a similar short-ranged structure to the completely dissociated fluid. We also construct a restricted primitive model for associating ionic species in an RTIL+solvent mixture. The double-layer formed i
An exploratory study on how Internet of Things developing companies handle User Experience Requirements
[Context and motivation]} Internet of Things (IoT) is becoming common throughout everyday lives. However, the interaction is often different from when using e.g. computers and other smart devices. Furthermore, an IoT device is often dependent on several other systems, heavily impacting the user experience (UX). Finally, the domain is changing rapidly and is driven by technological innovation. [Que
Special feature on heat: transdisciplinary approaches to climate change
Cognitive medicine - a new approach in health care science
Background: The challenges of today's society call for more knowledge about how to maintain all aspects of cognitive health, such as speed/attention, memory/learning, visuospatial ability, language, executive capacity and social cognition during the life course. Main text: Medical advances have improved treatments of numerous diseases, but the cognitive implications have not been sufficiently addr
Energy metabolic changes in the early post-injury period following traumatic brain injury in rats
Impaired cerebral energy metabolism may be a major contributor to the secondary injury cascade that occurs following traumatic brain injury (TBI). To estimate the cortical energy metabolic state following mild and severe controlled cortical contusion (CCC) TBI in rats, ipsi-and contralateral cortical tissues were frozen in situ at 15 and 40 min post-injury and adenylate (ATP, ADP, AMP) levels were
Animal modelling of traumatic brain injury in preclinical drug development : where do we go from here?
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults. Survivors of TBI frequently suffer from long-term personality changes and deficits in cognitive and motor performance, urgently calling for novel pharmacological treatment options. To date, all clinical trials evaluating neuroprotective compounds have failed in demonstrating clinical efficacy in cohorts of s
Interleukin-33 Promotes Recruitment of Microglia/Macrophages in Response to Traumatic Brain Injury
Traumatic brain injury (TBI) is a devastating condition, often leading to life-long consequences for patients. Even though modern neurointensive care has improved functional and cognitive outcomes, efficient pharmacological therapies are still lacking. Targeting peripherally derived, or resident inflammatory, cells that are rapid responders to brain injury is promising, but complex, given that the
Spaces of becoming: the Stockholm Film Workshop as a transnational site of film production
An account of the Stockholm Film Workshop (1973 - 2001) and how it became a site of film production by immigrant filmworkers, primarily from Latin America and Greece.
Med sinne för rättvisa - parallella normsystem och den uppochnervända världen
Rättspluralism i Indien
Water in Kazakhstan, a key in Central Asian water management
Central Asia is one of the regions with the highest probability of conflicts over water. Kazakhstan is the main Central Asian economic power and therefore it is important to understand how the country’s water management policy is influencing water availability in the other Central Asian states. Already, the Central Asian economies are developing under increasing water deficiency, resulting in deve
An Efficient Algorithm for Matrix-Valued and Vector-Valued Optimal Mass Transport
We present an efficient algorithm for recent generalizations of optimal mass transport theory to matrix-valued and vector-valued densities. These generalizations lead to several applications including diffusion tensor imaging, color image processing, and multi-modality imaging. The algorithm is based on sequential quadratic programming. By approximating the Hessian of the cost and solving each ite
Welcome to Hipsterville, In search of urban sustainable tourism.
Hipsterville has many locations, primarily in Europe and North America. The name of this ”place” refers tourban districts, mainly in large cities, which are dominated by particular subcultures. They are often formerworking class districts, in different stages of gentrification, located away from traditional tourism disticts. Inthese districts, clusters of small scale innovative firms may develop,
Family, Gender, and New Constellations: Crises and Changing Configurations in Late Đổi Mới Vietnam.
This chapter explores the ways in which ‘the family’ (gia đình) in late Đổi Mới Vietnam is undergoing transformations as a political institution, social organization, and lived experience. The notion of crisis, the chapter argues, provides an analytical vantage point to capture discrepancies between the ways in which the family is construed ideologically at the systemic level and how family life i
Tilltagande anemi och trombocytopeni hos gravida kan vara trombotisk trombocytopen purpura
New Quantitative Estimates of Long-Term Military Spending in Spain (1850–2009)
Contrasting patterns of Andean diversification among three diverse clades of Neotropical clearwing butterflies
The Neotropical region is the most biodiverse on Earth, in a large part due to the highly diverse tropical Andean biota. The Andes are a potentially important driver of diversification within the mountains and for neighboring regions. We compared the role of the Andes in diversification among three subtribes of Ithomiini butterflies endemic to the Neotropics, Dircennina, Oleriina, and Godyridina.
Mitophagy : A Mechanism for Plant Growth and Survival
Mitophagy is a conserved cellular process that is important for autophagic removal of damaged mitochondria to maintain a healthy mitochondrial population. Mitophagy also appears to occur in plants and has roles in development, stress response, senescence, and programmed cell death. However, many of the genes that control mitophagy in yeast and animal cells are absent from plants, and no plant prot
On the Calculation of SAXS Profiles of Folded and Intrinsically Disordered Proteins from Computer Simulations
Solution techniques such as small-angle X-ray scattering (SAXS) play a central role in structural studies of intrinsically disordered proteins (IDPs); yet, due to low resolution, it is generally necessary to combine SAXS with additional experimental sources of data and to use molecular simulations. Computational methods for the calculation of theoretical SAXS intensity profiles can be separated in