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Prevalence and determinants of differences in cystatin C and creatinine-based estimated glomerular filtration rate in community-dwelling older adults : A cross-sectional study

Background: Differences in cystatin C and creatinine-based estimated glomerular filtration rate (EGFR) can lead to clinical uncertainty. Existing EGFR equations perform poorly in a subset of individuals. This study aims to describe the prevalence of differences between cystatin C-based (EGFRcys) and creatinine-based (EGFRcreat) EGFR in older adults and to explore which subsets of individuals may b

Coordinated responses of natural anticoagulants to allogeneic stem cell transplantation and acute GVHD – A longitudinal study

Background Allogeneic stem cell transplantation (SCT) enhances coagulation via endothelial perturbation and inflammation. Role of natural anticoagulants in interactions between coagulation and inflammation as well as in acute graft-versus-host disease (GVHD) are not well known. The purpose of this study was to define changes in natural anticoagulants over time in association with GVHD. Patients an

From Twinning to Pure Zincblende Catalyst-Free InAs(Sb) Nanowires

III-V nanowires are candidate building blocks for next generation electronic and optoelectronic platforms. Low bandgap semiconductors such as InAs and InSb are interesting because of their high electron mobility. Fine control of the structure, morphology, and composition are key to the control of their physical properties. In this work, we present how to grow catalyst-free InAs1-xSbx nanowires, wh

Risk factors for recurrence in depression in the Lundby population, 1947–1997

Background Depression is a common disorder in both men and women, and the recurrence rate is high. The aim of this study was to identify risk factors for recurrence in depression in the Lundby Study. Methods The Lundby Study is a community-based longitudinal study with focus on mental health. The study started in 1947 and three follow-ups have been carried out since, the last one in 1997. The po

Early deficits in insulin secretion, beta cell mass and islet blood perfusion precede onset of autoimmune type 1 diabetes in BioBreeding rats

Aims/hypothesis: Genetic studies show coupling of genes affecting beta cell function to type 1 diabetes, but hitherto no studies on whether beta cell dysfunction could precede insulitis and clinical onset of type 1 diabetes are available. Methods: We used 40-day-old BioBreeding (BB) DRLyp/Lyp rats (a model of spontaneous autoimmune type 1 diabetes) and diabetes-resistant DRLyp/+ and DR+/+ litterma

Obesity and metabolic disturbances in adamantinomatous craniopharyngioma patients

An adamantinous craniopharyngioma (CP) is rare benign pituitary tumour often growing invasively and thereby affecting the hypothalamus. The recurrence rate in CP is high and therapy of choice is surgery, followed by cranial radiotherapy (CRT) in about half of the patients. Patients with CP have a 3-19 fold higher cardiovascular mortality in comparison to the general population. The majority of pat

Investigation of the Combustion Characteristics with Focus on Partially Premixed Combustion in a Heavy Duty Engine

Partially Premixed Combustion (PPC) has shown its potential by combining high combustion controllability with emission characteristics that are close to those of an HCCI engine. In order to get PPC the ignition delay needs to be long enough for the fuel and air to mix prior to combustion. This can be achieved by injecting the fuel sufficiently early while running with high EGR.In order to find outPartially Premixed Combustion (PPC) has shown its potential by combining high combustion controllability with emission characteristics that are close to those of an HCCI engine. In order to get PPC the ignition delay needs to be long enough for the fuel and air to mix prior to combustion. This can be achieved by injecting the fuel sufficiently early while running with high EGR.In order to find out

Closed-Loop Combustion Control for a 6-Cylinder Port-Injected Natural-gas Engine

High EGR rates combined with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy duty spark ignition engines. With stoichiometric conditions a three way catalyst can be used which means that regulated emissions can be kept at very low levels. Obtaining reliable spark ignition is difficult however with high pressure and dilution. There will be aHigh EGR rates combined with turbocharging has been identified as a promising way to increase the maximum load and efficiency of heavy-duty spark ignition engines. With stoichiometric conditions a three-way catalyst can be used which means that regulated emissions can be kept at very low levels. Obtaining reliable spark ignition is difficult however with high pressure and dilution. There will be a