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Longitudinal changes in weight in relation to smoking cessation in participants of the EPIC-PANACEA study

Purpose. We assessed the association between smoking cessation and prospective weight change in the European population of the European Prospective Investigation into Cancer and Nutrition-Physical Activity, Nutrition, Alcohol, Cessation of smoking. Eating out of home And obesity (EPIC-PANACEA) project. Methods. The study involved more than 300,000 healthy volunteers, recruited between 1992 and 200

Too heavy, too late: investigating perinatal health outcomes in immigrants residing in Spain. A cross-sectional study (2009-2011).

Studies have shown that immigrants residing in Spain have lower risks of delivering low birthweight (LBW) and preterm babies despite their socioeconomic disadvantages (the healthy migrant paradox). However, less is known about other important perinatal outcomes derived from birth weight and gestational age such as macrosomia and post-term birth. This paper aims to compare the main indicators relat

Identification of prostate specific antigen (PSA) isoforms in complex biological samples utilizing complementary platforms

Measurements of the prostate-specific antigen (PSA) levels in blood are widely used as diagnostic, predictive and prognostic marker of prostate disease. The selective detection of molecular forms of PSA can contribute clinically to meaningful enhancements of the conventional PSA-test. As it is plausible that an in-depth search for structural variants of PSA gene products may increase our ability t

Antifungal Properties of Wheat Histones (H1-H4) and Purified Wheat Histone H1

Wheat (Triticum spp.) histones H1, H2, H3, and H4 were extracted, and H1 was further purified. The effect of these histones on specific fungi that may or may not be pathogenic to wheat was determined. These fungi included Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger, Fusarium oxysporum, Fusarium verticillioides, Fusarium solani, Fusarium graminearum, Penicillium digitatum, Penicill

Opening of the abdomen ad modum Joel Cohen, Joel-Cohen, Joel Joel-Cohen, or just Cohen?

I recently bought a used book, a withdrawn ex-library copy of the second edition of Sidney Joel-Cohen's legendary textbook "Abdominal and Vaginal Hysterectomy. New Techniques Based on Time and Motion Studies" (1). The book is not only a masterpiece describing gynecological surgery techniques, my copy also has by written notes, stickers and stamps with a story to tell. The book is signed and was de

Acoustic radiation- and streaming-induced microparticle velocities determined by microparticle image velocimetry in an ultrasound symmetry plane

We present microparticle image velocimetry measurements of suspended microparticles of diameters from 0.6 to 10 mu m undergoing acoustophoresis in an ultrasound symmetry plane in a microchannel. The motion of the smallest particles is dominated by the Stokes drag from the induced acoustic streaming flow, while the motion of the largest particles is dominated by the acoustic radiation force. For al

Glucagon and GLP-1 exhibit no synergistic enhancement of glucose-stimulated insulin secretion in mice.

The combination of glucagon and glucagon-like peptide-1 (GLP-1) has been suggested as an approach to target obesity, since the two hormones have complementary action on body weight. We examined whether complementary action of the two hormones also exist on insulin secretion. Female C57BL/6 mice were injected intravenously with glucose with or without GLP-1, glucagon or the combination of GLP-1 and

Lymph node CEA and MUC2 mRNA as useful predictors of outcome in colorectal cancer

The aim was to explore the utility for staging and prognostic impact of carcinoembryonic antigen (CEA), cytokeratin 20 (CK20), guanylyl cyclase C (GCC), CUB (complement protein subcomponents C1r/C1s, urchin embryonic growth factor, and bone morphogenic protein 1) containing domain protein 1 (CDCP1) and mucin 2 (MUC2) mRNA levels in mesenteric lymph nodes of colorectal cancer (CRC) patients. Lymph

Allocation of carbon to mycorrhiza in the grasses Koeleria glauca and Corynephorus canescens in sandy grasslands

By investigating both semi-natural and experimentally implemented pH variation in nutrient-poor sandy grasslands, we examined how soil decalcification may influence the arbuscular mycorrhizal (AM) fungal biomass in plant roots and in the soil, as well as the allocation of carbon (C) to AM fungal biomass. We estimated the amount of AM fungal mycelium, by using the fatty acid 16:1 omega 5, in the ro

A Technique for Remote Detection of Certain Virtual Machine Monitors

The ability to detect a virtualized environment has both malicious and non-malicious uses. This paper reveals a new exploit and technique that can be used to remotely detect VMware Workstation, VMware Player and VirtualBox. The detection based on this technique can be done completely passively in that there is no need to have access to the remote machine and no network connections are initiated by

Aligning Nanodiscs at the Air-Water Interface, a Neutron Reflectivity Study

Nanodiscs are self-assembled nanostructures composed of a belt protein and a small patch of lipid bilayer, which can solubilize membrane proteins in a lipid bilayer environment. We present a method for the alignment of a well-defined two-dimensional layer of nanodiscs at the air-water interface by careful design of an insoluble surfactant monolayer at the surface. We used neutron reflectivity to d

Early life conditions and long-term sickness absence during adulthood - A longitudinal study of 9000 siblings in Sweden.

This study examines the influence of health conditions experienced during the individual's first year of life on the incidence of sickness absence during adulthood. Using a sample of approximately 9000 biological siblings from 17 countries of origin and living in Sweden during the time period 1981-1991, sibling fixed effect models are estimated. This approach is combined with the use of an exogeno

Fibroblast growth factor 21 prevents glycemic deterioration in insulin deficient mouse models of diabetes.

In type 1 diabetes, there is a rapid loss of glycemic control immediately after onset of the disease. We aimed to determine if the deterioration of glycemic control that occurs early after the onset of insulin-deficient diabetes could be blunted by treatment with recombinant fibroblast growth factor 21 (FGF21). Normal C57BL/6J mice made diabetic by a single high dose injection of streptozotocin (S

A cytochrome c- fusion protein domain for convenient detection, quantification and enhanced production of membrane proteins in Escherichia coli - expression and characterization of cytochrome-tagged complex I subunits

Overproduction of membrane proteins can be a cumbersome task, particularly if high yields are desirable. NADH:quinone oxidoreductase (complex I) contains several very large membrane-spanning protein subunits that hitherto have been impossible to express individually in any appreciable amounts in Escherichia coli. The polypeptides contain no prosthetic groups and are poorly antigenic, making optimi

Exogenous pancreatic-like enzymes are recovered in the gut and improve growth of exocrine pancreatic insufficient pigs

The exocrine pancreatic insufficient (EPI) pigs grow less due to different disturbances in feed digestion, absorption, and retention. Use of pancreatic-like enzymes of microbial origin in pigs may improve feed use and performance in slow-growing pigs. The aim was to study gut recovery and effectiveness of pancreatic-like enzymes of microbial origin supplementation on pig performance. Six male pigs

Exploring Nonverbal Behaviors in Elite Handball: How and When do Players Celebrate?

This study explores nonverbal behaviors in the form of gestures and touch during elite handball matches. Based on a coding scheme, 616 post-shot periods following a goal, stemming from 18 matches, were analyzed. Results revealed that on average 2.77 nonverbal behaviors were displayed after scoring. Playoff matches resulted in a higher average of nonverbal behaviors than league matches. The more a

Constant Mismatch Loss Boundary Circles and Their Application to Optimum State Distribution in Adaptive Matching Networks

An adaptive matching network provides a number of states between which it can be reconfigured. At a certain frequency, the matching network transforms a reference impedance to different impedances for the different states. The circuit will be able to match those impedances perfectly to the reference impedance, and impedances close to those will also be fairly well matched. The matching will, howev