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Staphylococcus aureus (S. aureus) is a notorious opportunistic foodborne pathogen and also a common cause of bovine mastitis. It is known to produce many different virulence factors, including various staphylococcal enterotoxins and toxic shock syndrome toxin-1 (TSST-1). The aim of this work was to investigate the regulation, expression, formation and role of S. aureus toxins in relation to food s

BACKGROUND: Guidelines recommend estimation of glomerular filtration rate (eGFR) prior to iodine contrast media (CM) examinations. It is also recommended that absolute eGFR in mL/min, not commonly used relative GFR (adjusted to body surface area; mL/min/1.73 m(2)), should be preferred when dosing and evaluating toxicity of renally excreted drugs.PURPOSE: To validate the absolute Lund-Malmö equatio

Cystatin C is produced in all nucleated cells. It has various functions and biological activities. Researchers are focused on its role in kidney diseases as a marker of glomerular filtration but also as a very important link in development of amyloid diseases. This work describes expression and purification of both wild type (wt) and stabilized form (stab 1 and 2) of wt cystatin C and amyloid-form

The (1)H NMR Fast Field Cycling relaxometry was applied to study the molecular dynamics of the human protein HC (alpha (1)-microglobulin), its hydration and aggregation in solution state. The (1)H NMRD data have revealed the complex nature of the water/protein HC system resulting from the co-existence of monomer and dimer forms of the protein in solution as well as the presence of oligosaccharides

Nettoprimärproduktionen (NPP), är källan till den mat vi äter, virket vi bygger hus av och veden vi eldar med. NPP spelar också en stor roll i den globala kolcykeln, genom fotosyntesen så binder växterna koldioxid från luften och producerar blad och stammar. Hur mycket växterna producerar styrs till stor utsträckning av klimatet samt hur mycket koldioxid som finns i atmosfären. Detta gör att de föNet primary production (NPP) serves as an indicator for plant-based resources such as food, timber and biofuel for human appropriation. It is defined by the annual production of plant matter and is mainly controlled by climate and human activities. Climate change in combination with human activities is altering NPP. As the controls of NPP are expected to further change in the future, it is vital t

In 1984, Richard Ruiz set forth three orientations to language planning: language as problem, language as right, and language as resource. Since that time, the orientations have only become more powerful, rising to the level of paradigm in the field of language policy and planning (LPP). In this paper, we revisit Ruiz’s orientations. By drawing upon Ruiz’s own work as well as the work of other sch

Glioblastoma (GBM), or WHO Astrocytoma grade IV, is the most common primary brain tumour in adults. GBM is shown to escape host immune surveillance through many paths, of which expression of indoleamine 2,3-dioxygenase (IDO), leading to induction and accumulation of regulatory T-cells in the tumour microenvironment, has been shown to be of importance. 1-Methyl tryptophan (1-MT) is an inhibitor of

Using high resolution X-ray photoelectron spectroscopy and scanning tunneling microscopy we study the intercalation of hydrogen under graphene/Ir(111). The hydrogen intercalated graphene is characterized by a component in C 1s that is shifted −0.10 to −0.18 eV with respect to pristine graphene and a component in Ir 4f at 60.54 eV. The position of this Ir 4f component is identical to that of the Ir

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine, hitherto mostly known to be involved in inflammatory responses and immunoregulation. The human tslp gene gives rise to two transcription and translation variants: a long form (lfTSLP) that is induced by inflammation, and a short, constitutively-expressed form (sfTSLP), that appears to be downregulated by inflammation. The TSLP forms ca