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Haemophilia B, an X-linked recessive bleeding disorder characterized by lack or deficiency of factor IX, has been shown to be caused by any of a variety of DNA abnormalities (partial or total deletions, nonsense or missense mutations). Since in most countries carrier detection is based on factor IX coagulant activity (FIX:C) assay, this study was designed to determine whether carriers' FIX:C value
Data from ice cores suggest that Late-glacial and early Holocene atmospheric CO2 variations were rather conservative, the most important change being a gradual Younger Dryas increase. By contrast, palaeo-CO2 records based on the inverse relationship between CO2 Partial pressure and stomatal frequency of terrestrial plant leaves reflect a more dynamic CO2 evolution, including an abrupt decrease at
In order to estimate the detention effect (storage and peak flow attenuation) of a sedum green-roof, a comparison between the response of an impervious roof (runoff coefficient C = 1) and a green-roof has been carried out. Precipitation and runoff data from several controlled experiments (with wet initial conditions, i.e. approximately at field capacity) on a sedum green-roof were used for the ana
The aim of this study was to examine biochemical changes in cell wall carbohydrates and extensin proteins during long-term storage of carrots (Daucus carota L. cv. Nerac). During the storage period of 6 months, cell wall fractions were isolated from the carrot at various times for carbohydrate and protein analysis. Signs of extensin cross-linking and its concomitant insolubilisation in the cell wa
A retrospective cohort study was performed in Sweden to evaluate the possibility that an individual symptom or constellation of illness symptoms related to silicone occurs in women after breast implant surgery. A random sample (n = 2500) of all women in the Swedish national implant registry who underwent breast augmentation surgery with alloplastic breast implants during the years 1965 through 199
Hormonal cancers such as breast and prostate cancer arise from steroid hormone-regulated tissues. In addition to breast and prostate cancer hormonal regulation has also a role in endometrial, ovarian, testis and thyroid carcinomas. The effects of estrogens, androgens and progestagens on tumor growth are largely mediated by paracrine and autocrine target molecules which include growth factors and g
We present a case of primary seminal vesicle carcinoma detected at transurethral resection. The clinical presentation, radiologic findings, and pathologic features of these tumors are reviewed. Grossly, seminal vesicle carcinoma is poorly circumscribed and solid or solid/cystic and may be misinterpreted as an abscess or hemorrhage on radiologic examination. Although a definitive diagnosis often ca
Type 1 fimbriae have been implicated as virulence factors in animal models of urinary tract infection (UTI), but the function in human disease remains unclear. This study used a human challenge model to examine if type 1 fimbriae trigger inflammation in the urinary tract. The asymptomatic bacteriuria strain Escherichia coli 83972, which fails to express type 1 fimbriae, due to a 4.25 kb fimB-fimD
A palynological analysis of a Lower Miocene cored section from Sonder Vium in western Jylland, Denmark, provides new data regarding the vegetation and climate during the earliest Neogene. Most samples yielded well-preserved palynomorphs. Terrestrial pollen and spores dominate, with lesser proportions of dinoflagellates. A fluvial input into the marine setting is corroborated by the presence of fre
A commercial biomedical poly(ether urethane), Pellethane 2363-80AE, was surface modified through the use of amphiphilic polymeric additives, and through surface grafting with poly(ethylene glycol), PEG. Two different amphiphilic polymers, Polymer C and Pluronic PE9400, were used as additives. Polymer C, a segmented polyurethane, was prepared from PEG1500, 4,4'-diphenylmethane diisocyanate and a C-
In a search for potential infertility loci, which might be revealed by clustering of chromosomal breakpoints, we compiled 464 infertile males with a balanced rearrangement from Mendelian Cytogenetics Network database (MCNdb) and compared their karyotypes with those of a Danish nation-wide cohort. We excluded Robertsonian translocations, rearrangements involving sex chromosomes and common variants.
Within the framework of an interdisciplinary project on the effects of climate and forest management on beech-dominated deciduous forests (Swabian Jura, south-western Germany), forest meteorological investigations are carried out to analyse the influences of exposure and canopy density on the microclimate within various beech stands (Fagus sylvatica L.). This second paper of the series ‘‘Microclimat
We construct Lie superalgebras osp(2n+1|4n+2) and osp(2n|4n) starting with certain classes of anti-structurable algebras via the standard embedding Lie superalgebra construction corresponding to (ε, δ)-Freudenthal Kantor triple systems.
Let G be a geometric t-spanner in E-d with n vertices and m edges, where t is a constant. We show that G can be preprocessed in O(m log n) time, such that (1 + epsilon)-approximate shortest-path queries in G can be answered in O(1) time. The data structure uses O(n log n) space.
Heterocyclic amines (HCAs) are potent mutagens/carcinogens to which humans are frequently exposed through the consumption of cooked meat and fish food. The effect of normal intake of HCAs and their role in the aetiology of human cancer is unknown. To some extent, limitations of the existing analytical methods in monitoring the low levels of HCAs in biological samples have hindered obtaining conclu
As has been commonly recognised, the Internet enables a transcendence of physical and national boundaries and therefore constitutes an ideal place for forging diasporic connections. There is no denying that the Internet has the potential to greatly affect how diasporic identities and senses of belonging are formed; the question is how, and in what online context? This article investigates a cluste
The relationship between triacylglycerol and monoacylglycerol hydrolyzing activities of purified rat heart lipoprotein lipase was studied using emulsified trioleoylglycerol and micellar or albumin-bound monooleoylglycerol as substrates. The maximal reaction rates obtained with the two substrates were similar (650 and 550 nmol of fatty acid released per min per mg of protein, respectively). Additio
An analysis of the backscattering data for the Schrodinger operator in odd dimensions n3 motivates the introduction of the backscattering transform [image omitted]. This is an entire analytic mapping and we write [image omitted] where BNv is the Nth order term in the power series expansion at v=0. In this paper we study estimates for BNv in H(s) spaces, and prove that Bv is entire analytic in vH(s
