Search results

Filter

Filetype

Your search for "*" yielded 534452 hits

Experimental evaluation of the effect of filtration of diesel exhaust by biologic exposure indicators

The airway resistance, compliance of the respiratory system, transfer factor, and alveolar volume of 33 healthy rabbits were studied before and after exposure to diluted diesel exhaust generated in an experimental motor. Three diesel fuels and two particle traps were tested. Subsequent to the post-exposure lung function measurements, the animals were sacrificed and the lungs were processed for mor

A general approach to the apparent permeability index

The apparent permeability index is widely used as part of a general screening process to study drug absorption, and is routinely obtained from in vitro or ex vivo experiments. A classical example, widely used in the pharmaceutical industry, is the in vitro Caco-2 cell culture model. The index is defined as the initial flux of compound through the membrane (normalized by membrane surface area and d

The extracellular matrix and inflammation - Fibromodulin activates the classical pathway of complement by directly binding C1q

Components that propagate inflammation in joint disease may be derived from cartilage since the inflammation resolves after joint replacement. We found that the cartilage component fibromodulin has the ability to activate an inflammatory cascade, i.e. complement. Fibromodulin and immunoglobulins cause comparable deposition of C1q, C4b, and C3b from human serum. Using C1q and factor B-deficient ser

A cinefluorographic study of the temporal organization of articulator gestures: Examples from Greenlandic

Movement data on articulator gestures in West Greenlandic are presented in order to elucidate principles of articulator coordination, especially the domain of coarticulation (as distinct from the domain of assimilation), the handling of conflicting demands on articulators, and the relation of vowels to consonants. The present data are consistent with results previously obtained from Swedish and Bu

Real-time extraction of maximally stable extremal regions on an FPGA

This paper describes the implementation of a real-time Maximally Stable Extremal Region (MSER) detector. In order to reach real-time performance, both algorithmic and memory issues have been addressed. The Union-find algorithm, which is the heart of the MSER detector, is extended to create linked regions that significantly decrease the time to extract MSERs. Hash indexed memory structures are used

Reduced frontotemporal perfusion in psychopathic personality

Several brain-imaging studies have found associations between aberrant functioning in the frontal and temporal lobes and violent offending. We have previously reported decreased frontotemporal perfusion unrelated to psychosis, substance abuse, or current medication in 21 violent offenders. In the present study, we compared the regional cerebral blood flow (rCBF) in a new group of 32 violent offend

Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin?

Interactions between plasma proteins and MPO were studied. The protein fraction of normal plasma and serum was shown to exhibit an inhibitory effect on the peroxidase activity of MPO. Most of the inhibitory effect could be retained on an MPO-coupled affinity chromatography column. In particular, a protein with apparent mol. wt of 130 kD showed affinity for MPO. The protein was identified as cerulo

Silent and Audible Persistent Ductus Arteriosus: An Angiographic Study.

Persistent ductus arteriosus (PDA) murmurs become silent probably due to the direction of the jet across the ductus arteriosus when entering the pulmonary artery. Out of 15 children with silent PDA, 14 demonstrated a ductal flow not contacting and away from the anterior wall of the main pulmonary artery. In 15 children with a continuous murmur caused by a PDA, 12 exhibited a ductal flow toward and

Multi-frequency response from a designed array of micromechanical cantilevers fabricated using a focused ion beam

We demonstrate arrays of cantilevers with different lengths, fabricated by focused ion beam milling. The arrays of oscillators generate a spectrum of different resonant frequencies, where each frequency correlates to the corresponding individual cantilever. The frequency response from all the cantilevers is collected from a single measurement under the same environment and conditions for the entir

Factors affecting time to pregnancy

BACKGROUND: Both lifestyle factors and occupational and environmental factors have been suggested to affect the female reproductive system. In the present study, the separate and joint effects of several such factors are investigated. METHODS: Information on time to pregnancy (TTP) was available for 1578 women randomly selected from the general Swedish population. The information was collected ret

Carpal tunnel syndrome and keyboard use at work - A population-based study

Objective. To investigate the relationship between carpal tunnel syndrome (CTS) and keyboard use at work in a general population. Methods. A health status questionnaire was mailed to 2,465 persons of working age (25-65 years) who were randomly selected from the general population of a representative region of Sweden. The questionnaire required the subjects to provide information about the presence

Principal components analysis of the impact of event scale with children in war

A new 13-item version of the Impact of Event Scale (Horowitz, Wilner, & Alvarez, 1979) was adminstered to 2976 9–14 year old children from Bosnia as part of a large epidemiological screening survey. The IES-13 consists of four intrusion items, four avoidance items, and five new arousal items. Factor analyses showed the scale to have an identical underlying factor structure as when it was used

Law as a gate keeper for participation. The case of 3G infrastructure development in Sweden

This article shows how participation on national, regional and local levels is regulated in the infrastructure of the third generation of mobile telephony, 3G, in Sweden. This regulated participation, the “law in books”, is compared to participation in practice, the “law in action” perspective in the sense of the outcome and functionality of these regulations. This includes the identification of i

Scandinavian relative clause extractions - Apparent restrictions

This brief article investigates the restrictions on Mainland Scandinavian relative clause extraction that have figured in the literature on island constraints. The conclusion is that none of these restrictions can be regarded as constraints on relative clause extraction per se and therefore that the peripheral status standardly assigned to Mainland Scandinavian relative clause extraction cannot be

Electroencephalography (EEG) for neurological prognostication after cardiac arrest and targeted temperature management; rationale and study design

Background: Electroencephalography (EEG) is widely used to assess neurological prognosis in patients who are comatose after cardiac arrest, but its value is limited by varying definitions of pathological patterns and by inter-rater variability. The American Clinical Neurophysiology Society (ACNS) has recently proposed a standardized EEG-terminology for critical care to address these limitations. I

Model-based analysis of the ventricular response during atrial fibrillation

We study a model of the atrioventricular node function during atrial fibrillation (AF), for which the model parameters can be estimated from the ECG. The proposed model is defined by parameters which characterize the arrival rate of atrial impulses, the probability of an impulse choosing either one of the two atrioventricular nodal pathways, the refractory periods of these pathways, and the prolon