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Patterns of pathologic lymph nodes in anal cancer : a PET-CT-based analysis with implications for radiotherapy treatment volumes

Background: This study investigates the patterns of PET-positive lymph nodes (LNs) in anal cancer. The aim was to provide information that could inform future anal cancer radiotherapy contouring guidelines. Methods: The baseline [18F]-FDG PET-CTs of 190 consecutive anal cancer patients were retrospectively assessed. LNs with a Deauville score (DS) of ≥3 were defined as PET-positive. Each PET-posit

The Struggles of Light Bound in Matter : Modelling Optical Excitations in Nanostructures

This thesis addresses three different topics on the interaction between light and matter in open quantum systems. The first topic concerns two-dimensional spectroscopy and the spectral contributions from different nonlinear action signals with a focus on how to differentiate between them. The second topic concerns the thermalization of excited electrons in hot-carrier solar cells with a focus on h

Inflows of foreign direct investments in Central Asian countries between 1991 and 2020

This report aims at identifying common causes, patterns, and effects of changing foreign investments across the countries of Central Asia. Experience of neighboring countries in Central Asia as a distinct region of the world attracting foreign investment is particularly relevant for each country in the area. Therefore, the comparative analysis of the Central Asian countries presented in this repor

Spectral characterization of magic angles in twisted bilayer graphene

Twisted bilayer graphene (TBG) has been experimentally observed to exhibit almost flat bands when the twisting occurs at certain magic angles. In this Letter we show that in the approximation of vanishing AA coupling, the magic angles (at which there exist entirely flat bands) are given as the eigenvalues of a non-Hermitian operator, and that all bands start squeezing exponentially fast as the ang

Respiratory Induced Modulation in f-Wave Characteristics During Atrial Fibrillation

The autonomic nervous system (ANS) is an important factor in cardiac arrhythmia, and information about ANS activity during atrial fibrillation (AF) may contribute to personalized treatment. In this study we aim to quantify respiratory modulation in the f-wave frequency trend from resting ECG. First, an f-wave signal is extracted from the ECG by QRST cancelation. Second, an f-wave model is fitted t

Genetic Diversity and Population Structure in Bryophyte With Facultative Nannandry

Among plants, gender dimorphism occurs in about 10% of all angiosperms and more than 50% of all moss taxa, with dwarf males (DM) found exclusively in some unisexual mosses. In this study, we explore the role of male dwarfism as a reproductive strategy in the widespread acrocarpous moss Dicranum scoparium, which has facultative male dwarfism, having both dwarf males (DMs) and normal-sized males (NM

Heart rate and adverse outcomes in patients with prevalent atrial fibrillation

OBJECTIVE: The optimal target heart rate in patients with prevalent atrial fibrillation (AF) is not well defined. The aim of this study was to analyse the associations between heart rate and adverse outcomes in a large contemporary cohort of patients with prevalent AF.METHODS: From two prospective cohort studies, we included stable AF outpatients who were in AF on the baseline ECG. The main outcom

Electronic correlations at paramagnetic (001) and (110) NiO surfaces : Charge-transfer and Mott-Hubbard-type gaps at the surface and subsurface of (110) NiO

We explore the interplay of electron-electron correlations and surface effects in the prototypical correlated insulating material, NiO. In particular, we compute the electronic structure, magnetic properties, and surface energies of the (001) and (110) surfaces of paramagnetic NiO using a fully charge self-consistent DFT+ dynamical mean-field theory method. Our results reveal a complex interplay b

Mediatisation and social sustainability – an ambivalent relationship

Mediatisation is one of the central concepts by which to understand how the intensifying media and communications environment constructs our social world. The aim of research is to examine the conditions of sustainability communication in a media economy of visibility and recognition. To this end, we focus on how the phenomenon overtourism is constructed as a social sustainability challenge in new

Neuronal Replacement in Stem Cell Therapy for Stroke : Filling the Gap

Stem cell therapy using human skin-derived neural precursors holds much promise for the treatment of stroke patients. Two main mechanisms have been proposed to give rise to the improved recovery in animal models of stroke after transplantation of these cells. First, the so called by-stander effect, which could modulate the environment during early phases after brain tissue damage, resulting in mod

The Other Side of SARS-CoV-2 Infection : Neurological Sequelae in Patients

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread around the globe causing coronavirus disease 2019 (COVID-19). Because it affects the respiratory system, common symptoms are cough and breathing difficulties with fever and fatigue. Also, some cases progress to acute respiratory distress syndrome (ARDS). The acute phase of COVID-19 has been also related to nervous system s

The effect of Lactiplantibacillus plantarum 299v together with a low dose of iron on iron status in healthy pregnant women : A randomized clinical trial

Introduction: Iron deficiency during pregnancy is a global health problem and is associated with adverse pregnancy outcomes. The aim of this randomized, double-blind, placebo-controlled study was to evaluate the effect of Lactiplantibacillus plantarum 299v (Lp299v, 1010 colony forming units), 4.2 mg iron, 12 mg ascorbic acid and 30 µg folic acid (Lp) on iron status in healthy, non-anemic, pregnant

Probing skin barrier recovery on molecular level following acute wounds : An in vivo/ex vivo study on pigs

Proper skin barrier function is paramount for our survival, and, suffering injury, there is an acute need to restore the lost barrier and prevent development of a chronic wound. We hypothesize that rapid wound closure is more important than immediate perfection of the barrier, whereas specific treatment may facilitate perfection. The aim of the current project was therefore to evaluate the quality

Acoustic-Pressure-Assisted Engineering of Aluminum Foams

Shaping metals as a foam modulates their physical properties, enabling attractive applications where lightweight, low thermal conductivity, or acoustic isolation are desirable. Adjusting the size of the bubbles in the foams is particularly relevant for targeted applications. Herein, a method with a detailed theoretical understanding of how to tune the size of the bubbles in aluminum melts in situ