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Intergenerational Transmission of Human Capital : Is it a One-Way Street?

Studies on the intergenerational transmission of human capital usually assume a one-way spillover from parents to children. However, children may also affect their parents’ human capital. Using exogenous variation in education, arising from a Swedish compulsory schooling reform in the 1950s and 1960s, we address this question by studying the causal effect of children's schooling on their parents’

Hybrid control of a manufacturing transport system

This paper describes the design of a least restrictive, safe hybrid control scheme for a manufacturing transport system transporting fragile objects from a production unit to a stamping/packaging station. The control scheme consists of several control modes. One control mode handles trajectory following using time-optimal control, the other control modes are safety related and are engaged in a lea

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This paper analyses the hegemony of the growth paradigm through the example of its naturalisation in capitalist production and consumption relations. Applying a combination of theoretical elements from the Marxian tradition, the Regulation approach and Bourdieusian sociology, emphasis is placed on how the growth imperative is reflected in people’s minds and bodies. It becomes hegemonic because it

Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

IMPORTANCE The clinical management of BRCA1 and BRCA2 mutation carriers requires accurate, prospective cancer risk estimates. OBJECTIVES To estimate age-specific risks of breast, ovarian, and contralateral breast cancer for mutation carriers and to evaluate risk modification by family cancer history and mutation location. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study of 6036 BRCA1 and

Constraining a terrestrial biosphere model with remotely sensed atmospheric carbon dioxide

We present two novel earth observation products derived from the BESD and EMMA XCO2 products which were respectively retrieved from SCIAMACHY and GOSAT observations within the GreenHouse Gas project of ESA's Climate Change Initiative (GHG-CCI). These products are inferred by a Carbon Cycle Data Assimilation System (CCDAS) and consist of net and gross biosphere-atmosphere fluxes of carbon dioxide o

Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma

Background: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of histone protein variants in PDAC patients. Methods: Liquid chromatography-tandem mass spectrometry (

Timing of oral anticoagulant therapy in acute ischemic stroke with atrial fibrillation : Study protocol for a registry-based randomised controlled trial

Background: Oral anticoagulation therapy is recommended for the prevention of recurrent ischemic stroke in patients with atrial fibrillation (AF). Current guidelines do not provide evidence-based recommendations on optimal time-point to start anticoagulation therapy after an acute ischemic stroke. Non-vitamin K antagonist oral anticoagulants (NOACs) may offer advantages compared to warfarin becaus

Arterial stiffness and incidence of diabetes : A population-based cohort study

Objective: Diabetes is known to be associated with increased arterial stiffness. However, the temporal association between increased carotid-femoral pulse wave velocity (c-f PWV) and diabetes is unclear. The aim of this study is to explore the relationship between arterial stiffness, as determined by c-f PWV, and incidence of diabetes. Research Design and Methods: The study population included par

Utvärdering av utvecklingsstatus för fuktanalysmetoder : Utvärdering och uppföljning av projektet CONMOD del II

Rapporten avser följa upp och utvärdera de resultat som kom från projektet CONMOD rörande fuktanalyser. I de sju rapporterna som har utgjort underlag för denna undersökning har står det generellt sett väldigt lite om fukt med två undantag. De två rapporter där det står mest om fukt och fuktmodellering, är dels i bilaga A5.4, i rapporten ”Barsebäck NPP- Material testing project”, Materialanalyser a

Verifiering av struktur och fuktmekaniska beräkningsverktyg : Tillämpning på reaktorinneslutningars betongkonstruktioner, Vercors Fas 1

Électricité de France har utanför Paris byggt en 1/3 skalmodell av en reaktorinneslutning motsvarande en fransk fullskalereaktor modell P4. Anläggningen möjliggör studier av hur åldringsprocesser påverkar förspända reaktorinneslutningar. Syftet är att efter de 7 år som ett övergripande forskningsprojektet vid på anläggningen pågår, uppnå påverkan motsvarande den åldring som en fullskalereaktor har

Combining shock barometry with numerical modeling : Insights into complex crater formation—The example of the Siljan impact structure (Sweden)

Siljan, central Sweden, is the largest known impact structure in Europe. It was formed at about 380 Ma, in the late Devonian period. The structure has been heavily eroded to a level originally located underneath the crater floor, and to date, important questions about the original size and morphology of Siljan remain unanswered. Here we present the results of a shock barometry study of quartz-bear

Dimethylguanidino valeric acid is a marker of liver fat and predicts diabetes

Unbiased, “nontargeted” metabolite profiling techniques hold considerable promise for biomarker and pathway discovery, in spite of the lack of successful applications to human disease. By integrating nontargeted metabolomics, genetics, and detailed human phenotyping, we identified dimethylguanidino valeric acid (DMGV) as an independent biomarker of CT-defined nonalcoholic fatty liver disease (NAFL

Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in size, including exosomes, microvesicles, and apoptotic bodies. They are released under physiological conditions, but also upon cellular activation, senescence, and apoptosis. They play an important role in intercellular communication. Their release may also maintain cellular integrity by ridding the cell of d

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease1. We conducted a GWAS using 21,468 ER-negative cases and 100,594 controls combined with 18,908 BRCA1 mutation carriers (9,414 with breast cancer), all of European origin. We identified independent associations at P < 5 × 10-8