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Impact of modern techniques on short-term outcome after surgery for primary hyperparathyroidism: a multicenter study comprising 2,708 patients.

PURPOSE: Preoperative localization procedures and the use of intraoperative parathyroidism (iOPTH) have led to a shift of paradigm from bilateral neck exploration to focused parathyroidectomy in primary hyperparathyroidism (pHPT). However, only a small number of randomized trials from specialized centers have been published. The main purpose of the study was to analyze the impact of localization p

Tracing pollution and recovery using sediments in an urban estuary, northern Baltic Sea: Are we far from ecological reference conditions?

One of the primary challenges of the Water Framework Directive (WFD) of the European Union is to provide a guide for the recovery of surface waters from pollution. However, few studies deal with reference conditions according to the WFD in coastal waters. Using the urbanised Laajalahti Bay (Helsinki, Finland) as an example, reference conditions and pollution history were defined using the stratigr

Resource Use in Patients with Psoriasis After the Introduction of Biologics in Sweden

The introduction of biologics has changed treatment patterns as well as costs in patients with psoriasis. This study was performed to estimate direct and indirect costs of the psoriasis population in Sweden, and to analyse changes in costs between 2006 and 2009. The study population was identified in national registers. Direct costs included health care visits with primary psoriasis diagnoses in s

Neonatal individualised care in practice, a Swedish experience

A family-centred, developmentally supportive approach to newborn intensive care referred to as NIDCAP (Newborn Individualized Developmental Care and Assessment Programme) has caught considerable interest during recent years. In this paper we review the scientific context behind its conceptual framework and summarize our experience from 10 years of training, implementation and research. We present

A statistical downscaling algorithm for thermal comfort applications

We describe a new two-step modeling framework for investigating the impact of climate change on human comfort in outdoor urban environments. In the first step, climate change scenarios for air temperature and solar radiation (global, diffuse, direct components) are created using a change-factor algorithm. The change factors are calculated by comparing ranked daily regional climate model outputs fo

Frontotemporal demens heterogen sjukdomsgrupp.

Frontotemporal lobar degeneration (FTLD) or frontotemporal dementia (FTD) is a clinically and neuropathologically heterogeneous group of primary degenerative dementia diseases. The clinical representation consists of progressive psychiatric and/or neurological symtoms such as behavioural changes, language or motor dysfunction. FTD is usually divided into the following subgroups: Behavioural varian

Computation of the M matrix for fourth-order problems

This paper is concerned with the numerical computation of the Titchmarsh-Weyl M matrix. We show how an algorithm may be developed which relates solutions of an initial-value problem to an approximation of the M matrix. In some special cases we compare the results from our algorithm with results obtained using special functions.

Tumour vessel damage resulting from laser-induced hyperthermia alone and in combination with photodynamic therapy

This study examined tumour vessel injury resulting from laser-induced hyperthermia alone and in combination with photodynamic therapy (PDT) in the treatment of rat liver tumours by means of scanning electron microscopy. A total of 18 Wistar rats were divided into three groups, Group I (six animals) underwent hyperthermia for 15 min (15-min hyperthermia). Group II (six animals) underwent hypertherm

Unconditional two-locus nonparametric linkage analysis

We discuss different aspects of unconditional two-locus nonparametric linkage (NPL) analysis with special emphasis on gene-gene interaction. We interpret this as identical-by-descent (IBD) sharing correlation between two disease loci both having marginal effect. We relate this to the concept of two-locus NPL score functions, the possible importance of using a composite rather than a simple null hy