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Supranational Influence in EU Enforcement: The ECJ and the Principle of State Liability

Existing research on supranational autonomy in the European Union (EU) is predominantly concerned with political and judicial agenda-setting, whereas the supranational institutions' capacity to exert independent influence in post-decisional enforcement has received more limited attention. Employing principal-agent analysis, this article explores an important component of the supranational institut

Effects of alpha-ketoglutarate on bone homeostasis and plasma amino acids in turkeys

The objective of the study was to evaluate the effect of denervation and alpha-ketoglutarate (AKG) administration on the development of osteopenia in the turkey radius. At 22 d of age, all turkeys were subjected to neurectomy of the right radius. Control turkeys were given a saline solution into the crop each day for 97 d. Experimental turkeys were given 0.4 g of AKG/kg of BW into the crop each da

Up-regulation of glucocorticoid-regulated genes in a mouse model of Rett syndrome

Rett syndrome (RTT) is a severe form of mental retardation, which is caused by spontaneous mutations in the X-linked gene MECP2. How the loss of MeCP2 function leads to RTT is currently unknown. Mice lacking the Mecp2 gene initially show normal postnatal development but later acquire neurological phenotypes, including heightened anxiety, that resemble RTT. The MECP2 gene encodes a methyl-CpG-bindi

Biologically mediated phosphorus precipitation in wastewater treatment with microalgae

A lab-scale continuous microalgal culture was grown on sterile-filtered wastewater in order to clarify the phosphorus removing mechanisms in a microalgal treatment step that treats residual phosphorus from a hydroponic wastewater treatment pilot plant. The phosphorus assimilation was dependent on algal biomass production, whereas the chemical precipitation was dependent on phosphorus load, i.e. an

Patients perceptions of information about risks at cardiac surgery

Objective: The aim was to describe the patients' own experiences of risk information in connection with cardiac surgery and it's outcome. Methods: Questionnaires were answered prior to and 8 weeks after cardiac surgery. Data were analysed using qualitative content analysis. Patients in the intervention group (n = 55) received standard information and a newly written extended information brochure a

Effects of isradipine, a new calcium antagonist, on maternal cardiovascular system and uterine activity in labour

The effects of isradipine (a new calcium antagonist of the dihydropyridine type) on maternal blood pressure and heart rate, fetal heart rate, and uterine activity in labour were measured. Uterine activity was recorded by an intrauterine microtip transducer catheter connected to a fetal monitor. Isradipine was given as a slow injection in doses of 0.5 mg (10 women), 1 mg (11 women), and 1.5 mg (6 w

Correlation attacks using a new class of weak feedback polynomials

In 1985 Siegenthaler introduced the concept of correlation attacks on LFSR based stream ciphers. A few years later Meier and Staffelbach demonstrated a special technique, usually referred to as fast correlation attacks, that is very effective if the feedback polynomial has a special form, namely, if its weight is very low. Due to this seminal result, it is a well known fact that one avoids low wei

Primula elatior found at lake Ringsjön, Scania

A small population of Primula elatior has recently been found in a virgin swampy forest close to the southeastern shore of lake Ringsjon in Stehag parish. Here it grows in fully natural vegetation together with e.g. Anemone ranunculoides, Paris quadrifolia, Listera ovata, Ranunculus auricomus and Viola epipsila and there are no reasons to suspect that the population is anything but spontaneous. Un

An integral operator on $H\sp p$

To every analytic function $g$ in the unit disk $\bold D$ one associates the integral operator $T_g(f)(z)\coloneq z^{-1}\int^z_0f(\xi)g'(\xi)d\xi$ on spaces of analytic functions in $\bold D$. Operators of this form appear naturally in complex analysis. For instance, the choice $g(z)\equiv z$ leads to the integration operator, and the choice $g(z)=\log(1/(1-z))$ leads to the Cesàro operator. The

Humoral immunity targeting site I of antigenic domain 2 of glycoprotein B upon immunization with different cytomegalovirus candidate vaccines.

Glycoprotein B (gB) is a major component in several vaccines that are under development for prevention of disease by cytomegalovirus. It contains multiple determinants that are targets for neutralizing antibodies. One of them is site I of antigenic domain 2 (AD-2). The epitope, defined by short peptides, is quite conserved between different isolates. However, it is poorly immunogenic in natural in

Multiple-gradient array measurements for multichannel 2D resistivity imaging

Two-dimensional resistivity imaging using multiple gradient, Wenner and dipole-dipole electrode arrays was carried out at two field sites in Sweden and one in Nicaragua, with the objective of confirming the practical applicability of results obtained with numerical modelling. The results support earlier numerical modelling studies that concluded that the gradient array, using multiple current elec

Seizure-induced differential expression of messenger RNAs for neurotrophins and their receptors in genetically fast and slow kindling rats

Levels of messenger RNAs for brain-derived neurotrophic factor, nerve growth factor and neurotrophin-3, and their high-affinity receptors, TrkB and TrkC, were analysed in the brains of genetically fast and slow kindling rats using in situ hybridization. Basal expression of neurotrophins and Trk messenger RNAs in the hippocampal formation, amygdala, frontoparietal and piriform cortices did not diff

Tympanic membrane changes in experimental acute otitis media and myringotomy

Objective. The present experimental study explored pathomorphological changes and calcium depositions in the tympanic membrane during experimental acute otitis media caused by nontypeable Haemophilus influenzae in myringotomized and nonmyringotomized ears. Material and methods. A rat model of experimental acute otitis media caused by nontypeable Haemophilus influenzae was employed Sixteen Sprague-

Are birds stressed during long-term flights? A wind-tunnel study on circulating corticosterone in the red knot

During endurance flight most birds do not feed and have to rely on their body reserves. Fat and protein is catabolised to meet the high energetic demands. Even though the hormonal regulation of migration is complex and not yet fully understood. the adrenocortical hormone corticosterone crystallizes to play a major role in controlling physiological traits in migratory birds during flight. However,

Laminin {alpha}1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

basement membrane (BM) assembly, which is required for pregastrulation development. Individual domains may have other functions, not necessarily structural. The cell binding C terminus of Lm {alpha}1 chain contains five Lm globular (LG) domains. In vitro, {alpha}1LG1–3 domains bind integrins, and {alpha}1LG4 binds dystroglycan, heparin, and sulfatides. A prevailing hypothesis is that {alpha}1LG4 i

Staff experience and understanding of working with abused women suffering from mental illness

The phenomenon of abused women with mental illness is often unrecognised by staff working within welfare services. This may be explained by staff members' attitudes, insecurity or lack of awareness. Today, there are shortcomings in the knowledge of staff members' experiences and interpretations of abuse against women suffering from mental illness. The aim of this qualitative study was to describe

A prospective population-based management program including primary surgery and postoperative risk assessment by means of DNA ploidy and histopathology. Adjuvant radiotherapy is not necessary for the majority of patients with FIGO stage I-II endometrial cancer

A management program for FIGO stage I-II nonserous, nonclear-cell adenocarcinomas was evaluated. Histopathology and DNA ploidy were used to estimate postoperatively the risk of progression or death of disease and to tailor treatment. The patient material was a population-based consecutive cohort of all women with endometrial cancer in the Southern Swedish Health Care Region diagnosed between June

PITX2 isoform-specific regulation of atrial natriuretic factor expression - Synergism and repression with Nkx2.5

PITX2 and Nkx2.5 are two of the earliest known transcriptional markers of vertebrate heart development. Pitx2(-/-) mice present with severe cardiac malformations and embryonic lethality, demonstrating a role for PITX2 in heart development. However, little is known about the downstream targets of PITX2 in cardiogenesis. We report here that the atrial natriuretic factor ( ANF) promoter is a target o