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Effects of restricted diffusion in a biological phantom: a q-space diffusion MRI study of asparagus stems at a 3T clinical scanner

Introduction The aim of this work was to study the effects of restricted diffusion in a biological phantom consisting of green asparagus stems using q-space MRI at a clinical scanner. Method Measurements of the full width at half maximum (FWHM) of the displacement distribution were performed with varied diffusion time (T d). The accuracy of the measurements was investigated with respect to the deg

Human sputum cathepsin B degrades proteoglycan, is inhibited by a2-macroglobulin and modulated by neutrophil elastase cleavage of cathepsin B precursor and cystatin C

The high-Mr alkali-stable form of cathepsin B was purified from purulent human sputum. It was shown to solubilize proteoglycan monomer entrapped in polyacrylamide at a rate comparable with that of human lysosomal cathepsin B. Like the enzyme from lysosomes, sputum cathepsin B was bound by human alpha 2-macroglobulin, which inhibited its action on proteoglycan. Cystatin C in purulent sputum was sho

Coherent transport through an interacting double quantum dot: Beyond sequential tunneling

Various causes for negative differential conductance in transport through an interacting double quantum dot are investigated. Particular focus is given to the interplay between the renormalization of the energy levels due to the coupling to the leads and the decoherence of the states. The calculations are performed within a basis of many-particle eigenstates and we consider the dynamics given by t

"NeuroStem Chip": a novel highly specialized tool to study neural differentiation pathways in human stem cells.

BACKGROUND: Human stem cells are viewed as a possible source of neurons for a cell-based therapy of neurodegenerative disorders, such as Parkinson's disease. Several protocols that generate different types of neurons from human stem cells (hSCs) have been developed. Nevertheless, the cellular mechanisms that underlie the development of neurons in vitro as they are subjected to the specific differe

PITX genes are required for cell survival and Lhx3 activation.

The PITX family of transcription factors regulate the development of many organs. Pitx1 mutants have a mild pituitary phenotype, but Pitx2 is necessary for the development of Rathke's pouch, expression of essential transcription factors in gonadotropes, and expansion of the Pit1 lineage. We report that lack of Pitx2 causes the pouch to undergo excessive cell death, resulting in severe pituitary hy

The effect of endothelin receptor blockade on the development of the Sephadex-induced inflammation in the rat lung

The non-peptide ET-receptor antagonist Bosentan was used to investigate the role of endogenous endothelin-1 (ET-1) in the development of the Sephadex-induced lung inflammation in the rat. Intratracheal instillation of Sephadex caused a 60-fold rise in endothelin-1-like-immunoreactivity (ET-1-LI) in bronchoalveolar lavage fluid (BALF) concomitant with development of lung oedema, an influx of inflam

NSAID visar övertygande effekt vid postoperativ smärta

Non-steroidal antiinflammatory drugs (NSAID) are increasingly being included in the management of postoperative pain as part of a multimodal therapeutic approach. However, there is an ongoing debate among clinicians as to the perioperative use of NSAID's as many authors have cautioned against their use in this setting. Concerns about their impact on coagulation and renal function as well as a risk

Klimatdata för fuktberäkningar - Fuktsäkerhet i byggnader

Syftet med denna skrift är att exemplifiera hur man kan välja klimatdata för olika beräkningar som bör genomföras vid en fuktdimensionering. Klimatparametrarna finns sammanställda i ett PC-program som heter KLIMATDATA. Programmet är fritt tillgängligt att hämta hem. Värdena på de olika klimatparametrarna är sammanställda från tio olika meteorologiska mätstationer i Sverige för 30-årsperioden 1961-

Galerkin/Runge-Kutta discretizations of nonlinear parabolic equations

Global error bounds are derived for full Galerkin/Runge-Kutta discretizations of nonlinear parabolic problems, including the evolution governed by the p-Laplacian with p >= 2. The analysis presented here is not based on linearization procedures, but on the fully nonlinear framework of logarithmic Lipschitz constants and an extended B-convergence theory. The global error is bounded in L-2 by Delta

Uninterpretable features and EPP: a minimal account of language build up and break down

Like most L2 speakers, speakers of early L1, children with SLI, and Broca’s aphasics lack the or¬dinary speaker’s ability to produce utterances on line with almost no errors. Often they produce well-formed utterances, but quite frequently they produce errors that are almost non-existent in the speech of normal grown-up speakers. In my paper I will suggest, based on empirical material from Swedish,

Cerebrospinal fluid protein reactions during non-neurological surgery

Objective- To study changes in cerebrospinal fluid (CSF) protein markers of blood-CSF barrier integrity and immunological reactions during surgical stress. Methods- Thirty-five patients without neurological or psychiatric disorders undergoing knee replacements had CSF and serum samples drawn from spinal and arterial catheters before, 3 h after and the morning after surgery. Results- Serum albumin

Compatibility between flooring materials on concrete - development of test method

I syfte att utveckla en ny provningsmetod för golvmaterial/system på betong beträffande fläkningskraft, relativ fuktighet och emissioner av organiska ämnen studerades 60 provkroppar. Provkroppen, tre identiskt lika av vardera i syfte att studera noggrannheten, byggdes upp som ett verkligt golv inuti en stålform (standard ventilationsdelar i stål - lock och fläns) vilken satt kvar under hela testpe

A determination of electroweak parameters at HERA

Using the deep inelastic e(+) p and e(-) p charged and neutral current scattering cross sections previously published, a combined electroweak and QCD analysis is performed to determine electroweak parameters accounting for their correlation with parton distributions. The data used have been collected by the HI experiment in 1994-2000 and correspond to an integrated luminosity of 117.2 pb(-1). A me

Hygiene in warewashers utilizing blasting granules that foodservice establishments use.

Four kitchens, each with a different work load, were used to evaluate the microbiological risk of utilizing blasting granules in a new type of warewash machine. The granules, plastic pellets 3.5 - 3.5 mm, are recirculated together with the dishwater in the machine, and when the dishwater is expelled, the granules remain in the machine until the next day. Samples of soiled dishwater and tap water w