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Androgens in women after allogeneic hematopoietic cell transplantation : Impact of chronic GvHD and glucocorticoid therapy

Low androgen levels may contribute to sexual dysfunction in women after allogeneic hematopoietic cell transplantation (alloHCT). However, data on serum androgens in women after alloHCT are limited. The aim of this study was to assess androgen levels and their association with chronic GvHD (cGvHD) and glucocorticoid (GC) therapy. Included were 65 allografted women, 33 with cGvHD, and 23 of these we

'Be Creative!' : Control, Demand, Hypocrisy, and the Management of Creativity

Our paper challenges the “romantic” notion of creativity being good and liberating. Interpreting the empirical evidences from two organizations, based in India and Sweden, respectively, it presents how creativity and creative process are strangling because they are controlled and demanded in organizations. In doing so, we put forth the idea of hypocritical creativity in organizations. Our study hi

The Efficiency Paradox in Organization and Management Theory

We theoretically discuss a phenomenon that we label “efficiencyism”. Efficiencyism describes a fixation on reified tenets of efficiency without questioning its assumptions and consequences. In organization and management theory efficiency is a foundational concept, which is assumed to be vital for economic success based on the optimization of input-output ratios. Based on the logic of the Jevons P

Probing the dynamics of complexed local anesthetics via neutron scattering spectroscopy and DFT calculations

Since potential changes in the dynamics and mobility of drugs upon complexation for delivery may affect their ultimate efficacy, we have investigated the dynamics of two local anesthetic molecules, bupivacaine (BVC, C18H28N2O) and ropivacaine (RVC, C17H26N2O), in both their crystalline forms and complexed with water-soluble oligosaccharide 2-hydroxypropyl-β-cyclodextrin (HP-β-CD). The study was ca

Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus

Objectives Belimumab is the first biologic drug approved for Systemic Lupus Erythematosus (SLE). Here, we aimed to investigate the effects of belimumab on clinical and serologic outcomes, and sought to identify predictors of treatment response in three Swedish real-life settings. Methods Fifty-eight patients were enrolled at initiation of belimumab and followed longitudinally for up to 53 months.

The challenge of alignment and barriers for the design and implementation of science, technology and innovation policies for innovation systems in developing countries

This chapter aims at discussing the main challenges of designing and implementing science, technology and innovation (STI) policies in developing countries. In particular, it addresses the problems of: a) aligning STI policies with the national economic development agenda, as well as coordinating STI policies among different ministries and other public organizations, and among diverse government l

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Evaluation of anti-proliferative effect of BSA-1 and 32/26/2B in Y79 retinoblastoma cancer cells.

Det omstridda arvet : Den kommunistiska erfarenheten i dansk och svensk historiekultur

This thesis investigates the dissension and dividing force present with regard to dealing with the communist experience in Sweden andDenmark. It studies the manifestations and causes of this dissension and compares the ways it has been dealt with in historical culture. 38in-depth interviews with history teachers and historical scholars, belonging to two generations, have been conducted. They have