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Smoking and pre-existing organ damage reduce the efficacy of belimumab in systemic lupus erythematosus

Objectives Belimumab is the first biologic drug approved for Systemic Lupus Erythematosus (SLE). Here, we aimed to investigate the effects of belimumab on clinical and serologic outcomes, and sought to identify predictors of treatment response in three Swedish real-life settings. Methods Fifty-eight patients were enrolled at initiation of belimumab and followed longitudinally for up to 53 months.

The challenge of alignment and barriers for the design and implementation of science, technology and innovation policies for innovation systems in developing countries

This chapter aims at discussing the main challenges of designing and implementing science, technology and innovation (STI) policies in developing countries. In particular, it addresses the problems of: a) aligning STI policies with the national economic development agenda, as well as coordinating STI policies among different ministries and other public organizations, and among diverse government l

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Evaluation of anti-proliferative effect of BSA-1 and 32/26/2B in Y79 retinoblastoma cancer cells.

Det omstridda arvet : Den kommunistiska erfarenheten i dansk och svensk historiekultur

This thesis investigates the dissension and dividing force present with regard to dealing with the communist experience in Sweden andDenmark. It studies the manifestations and causes of this dissension and compares the ways it has been dealt with in historical culture. 38in-depth interviews with history teachers and historical scholars, belonging to two generations, have been conducted. They have

Tuning Crystal Structures and Thermoelectric Properties through Al Doping in ReSi1.75

Binary rhenium silicide, ReSi1.75, and its aluminium-doped variants have been synthesized. Their crystal structures were characterized by X-ray diffraction, solved and refined through the use of superspace group models. The binary undoped ReSi1.75 is a commensurate (supercell) structure of the previously well-known MoSi2-type structure. Al doping renders an incommensurate structure that was solved

III-V heterojunction nanowire tunnel FETs monolithically integrated on silicon

In this presentation we will discuss our recent progress on the integration of InAs/Si p-tunnel FETs (TFETs) and InAs/GaSb n-TFETs on SOI wafers. Local III-V growth is enabled by the development of Template-Assisted Selective Epitaxy (TASE) [1-4]. Both polarity devices have scaled geometries with cross-sections on the order of 30nm. The p-channel InAs/Si TFETs are developed based on our previously

Assessment of hygrothermal performance and mould growth risk in ventilated attics in respect to possible climate changes in Sweden

Most of the last 20 years in Sweden have been mild and wet compared to the 1961-1990 climate reference period. After a few relatively cold years in the mid-1980s, practically all years have been warmer than the preceding 30 years average. During the indicated period, an increase of moisture-related problems (mould growth) was observed in ventilated attics, a moisture sensitive building part.This w