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Stimuli-controlled self-assembly of diverse tubular aggregates from one single small monomer

The design and synthesis of new stimuli-responsive hydrogen-bonding monomers that display a diversity of self-assembly pathways is of central importance in supramolecular chemistry. Here we describe the aggregation properties of a simple, intrinsically C2-symmetric enantiopure bicyclic cavity compound bearing a terminally unsubstituted ureidopyrimidinone fragment fused with a pyrrole moiety in dif

Structural and magnetic properties of multi-core nanoparticles analysed using a generalised numerical inversion method

The structural and magnetic properties of magnetic multi-core particles were determined by numerical inversion of small angle scattering and isothermal magnetisation data. The investigated particles consist of iron oxide nanoparticle cores (9 nm) embedded in poly(styrene) spheres (160 nm). A thorough physical characterisation of the particles included transmission electron microscopy, X-ray diffra

The impacts of organisational justice and psychological resilience on employee commitment to change in an M&A context

Many firms have carried out organisational change, such as mergers and acquisitions, to adapt to the rapidly changing business environment. During such changes, it is crucial for firms to provide an environment that will enhance employees’ psychological stability and commitment to change. Therefore, this study explores factors that increase employee commitment to change during mergers and acquisit

An estimated 400-800 million tons of prey are annually killed by the global spider community

Spiders have been suspected to be one of the most important groups of natural enemies of insects worldwide. To document the impact of the global spider community as insect predators, we present estimates of the biomass of annually killed insect prey. Our estimates assessed with two different methods suggest that the annual prey kill of the global spider community is in the range of 400-800 million

Systematic evaluation of skeletal fractures caused by induction of electroconvulsive seizures in rat state a need for attention and refinement of the procedure

Objective: Electroconvulsive therapy (ECT) is one of the most efficient treatments for major depression. Electroconvulsive seizures (ECS), the animal model of ECT, is widely used to study both mechanisms of action and adverse effects of ECT. As the treatment itself serves as an instant anaesthetic and anaesthetic agents may affect memory functions and behaviour, ECS is traditionally administered w

Risk of Abdominal Surgery in Pregnancy Among Women Who Have Undergone Bariatric Surgery

OBJECTIVE:: To compare the rates of abdominal surgery during pregnancy among women with previous bariatric surgery (women in the case group) and women with first-trimester body mass index (BMI) greater than 35 and no previous bariatric surgery (women in the control group). METHODS:: We conducted a national cohort study, merging data from the Swedish Medical Birth Registry and the Swedish National

Exposure to bacterial products lipopolysaccharide and flagellin and hepatocellular carcinoma : A nested case-control study

Background: Leakage of bacterial products across the gut barrier may play a role in liver diseases which often precede the development of liver cancer. However, human studies, particularly from prospective settings, are lacking. Methods: We used a case-control study design nested within a large prospective cohort to assess the association between circulating levels of anti-lipopolysaccharide (LPS)

Blending DNA binding dyes to improve detection in real-time PCR

The success of real-time PCR (qPCR) analysis is partly limited by the presence of inhibitory compounds in the nucleic acid samples. For example, humic acid (HA) from soil and aqueous sediment interferes with amplification and also quenches the fluorescence of double-stranded (ds) DNA binding dyes, thus hindering amplicon detection. We aimed to counteract the HA fluorescence quenching effect by ble

Swelling and Microstructure of Nanoplatelet Systems

De flesta anser nog att kemi och speciellt teoretisk kemi är ett mycket komplext ämne, medan lera nog anses som ett begripligt koncept. Det man kanske inte tänker på är att många leror utgörs till stor del av elektrostatiskt laddade nanopartiklar där dess beteende kan förstås genom just ämnena kemi och teoretisk kemi. De laddade nanopartiklarna, även kallade lerplattor, är formade som tunna pannkaMany clay minerals consist of charged nanoplatelets that swell in an aqueous solution. The swelling and the microstructure depend on the type of clay mineral but are also dependent on, for example, the ionic composition and the temperature of the solution. The synthetic clay mineral Laponite and the natural clay mineral montmorillonite have been studied experimentally and theoretically. The swelli

Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer

There is a demand for novel targets and approaches to diagnose and treat prostate cancer (PCA). In this context, serum and plasma samples from a total of 609 individuals from two independent patient cohorts were screened for IgG reactivity against a sum of 3833 human protein fragments. Starting from planar protein arrays with 3786 protein fragments to screen 80 patients with and without PCA diagno

FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells

The drug FK506 (tacrolimus, fujimycin) exerts its immunosuppressive effects by regulating the nuclear factor of the activated T-cell (NFAT) family of transcription factors. However, FK506 also exhibits neuroprotective effects, but its direct target proteins that mediate these effects have not been determined. To identify the target proteins responsible for FK506's neuroprotective effects, the drug

Partisanship and unreformed bureaucracy : The drivers of election fraud in Sweden, 1719–1908

This paper explains election fraud historically in the case of Sweden, drawing on original data from second-instance election petitions filed in 1719–1908. These petitions reveal systematic procedural violations committed by local election officials toward the end of the Age of Liberty in the eighteenth century. By the mid-nineteenth century, however, fraud had been largely purged from Swedish ele

A future for facility management

Purpose: This paper aims to discuss the current debates in facility management to understand where the research community is working and where the facility management sector and discipline might be heading. Design/methodology/approach: A review of research outputs has been undertaken to identify research themes. The discussion is based on developments that are already shaping how one should view f