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On the physico-chemical properties of softwood hemicellulose and compounds derived from it

Hemicellulose is the second largest polysaccharide group available in nature after cellulose. Hemicellulose is present in plant cell walls along with cellulose and lignin. It is an abundant and biodegradable material that could potentially replace fossil-based products. The focus of this thesis is the properties and valorization of softwood hemicellulose (galactoglucomannan).In the first part of t

Prospective validation of microseminoprotein-β added to the 4Kscore in predicting high-grade prostate cancer in an international multicentre cohort

Objectives: To prospectively evaluate the performance of a pre-specified statistical model based on four kallikrein markers in blood (total prostate-specific antigen [PSA], free PSA, intact PSA, and human kallikrein-related peptidase 2), commercially available as the 4Kscore, in predicting Gleason Grade Group (GG) ≥2 prostate cancer at biopsy in an international multicentre study at three academic

Predicting the rate of oxygen consumption during the 3-minute constant-rate stair stepping and shuttle tests in people with chronic obstructive pulmonary disease

Background: The 3-minute constant-rate stair stepping (3-min CRSST) and constant-speed shuttle tests (3-min CSST) were developed to assess breathlessness in response to a standardized exercise stimulus. Estimating the rate of oxygen consumption (V'O2) during these tests would assist clinicians to relate the stepping/shuttle speeds that elicit breathlessness to daily physical activities with a simi

Research of the NUSTAR departments : SHE departments and HIM SHE section

The SHE departments devoted to the research of superheavy elements, operate the recoil separators SHIP and TASCA and their ancillary installations including SHIPTRAP and a laser spectroscopy setup at SHIP as well as chemistry and nuclear spectroscopy setups at TASCA. In 2019, the activities at GSI focused on the UNILAC beamtime within the FAIR Phase-0 program and on the analysis of data obtained i

Increased effect of two-fraction radiotherapy in conjunction with IDO1 inhibition in experimental glioblastoma

Objectives The aim of the study was to investigate therapeutic efficacy of single-or two-fraction radiotherapy in conjunction with IDO1-inhibition in a syngeneic rat glioblastoma model. IDO is known to cause immunosuppression through breakdown of tryptophan in the tumor microenvironment. Methods Gene expression analyses of IDO in glioblastoma were performed with data from publicly available datase

The Dark Cube : dark character profiles and OCEAN

BACKGROUND: The Big Five traits (i.e., openness, conscientiousness, extraversion, agreeableness, and neuroticism: OCEAN) have been suggested to provide a meaningful taxonomy for studying the Dark Triad: Machiavellianism, narcissism, and psychopathy. Nevertheless, current research consists of mixed and inconsistent associations between the Dark Triad and OCEAN. Here we used the Dark Cube (Garcia &a

The energy transition in the Swedish iron and steel sector, 1800– 1939

This article analyses the energy transition of the Swedish iron and steel industry (1800–1939), a leading actor in the European iron and steel market during the 19th and 20th centuries.This industry is an interesting case to analyse from the perspective of energy transition and the composition and change of capital stock (classified by energy technology). in-depth review of the this topic will ena

Economical effect on doubling of COVID-19 cases : Examples of rich versus poor countries

PurposeThe paper aims to examine some economical, political and health system indicators on the transmission of the COVID-19 transmission within the national system. The main objective is to investigate what are the most effective indicators which have led to the declared numbers by countries.Design/methodology/approachThis study combined multiple sets of data to describe best the economical statu

Evaluating competition for forage plants between honey bees and wild bees in Denmark

A recurrent concern in nature conservation is the potential competition for forage plants between wild bees and managed honey bees. Specifically, that the highly sophisticated system of recruitment and large perennial colonies of honey bees quickly exhaust forage resources leading to the local extirpation of wild bees. However, different species of bees show different preferences for forage plants

Coupling Microplate-Based Antibacterial Assay with Liquid Chromatography for High-Resolution Growth Inhibition Profiling of Crude Extracts : Validation and Proof-of-Concept Study with Staphylococcus aureus

With the identification of novel antibiotics from nature being pivotal in the fight against human pathogenic bacteria, there is an urgent need for effective methodologies for expedited screening of crude extracts. Here we report the development and validation of a simple and dye-free antimicrobial assay in 96-well microplate format, for both determination of IC50 values and high-resolution inhibit

Dietary quercetin impacts the concentration of pesticides in honey bees

Honey bees are important pollinators and are subject to numerous stressors, such as changing floral resources, parasites, and agrochemical exposure. Pesticide exposure has been linked to the decline in the global honey bee population. We have limited knowledge of the metabolic pathways and synergistic effects of xenobiotics in bees. Quercetin is one of the most abundant phytochemicals in plants an