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Predictors of short-term anxiety outcome in subthalamic stimulation for Parkinson’s disease

The effects of subthalamic nucleus deep brain stimulation (STN-DBS) on anxiety in Parkinson’s disease (PD) are understudied. We identified clinical predictors of STN-DBS effects on anxiety in this study. In this prospective, open-label, multicentre study, we assessed patients with anxiety undergoing STN-DBS for PD preoperatively and at 6-month follow-up postoperatively. We assessed the Hospital An

Amniotic fluid derived mesenchymal stem cells reduce inflammation and improve lung function following transplantation in a porcine model

BACKGROUND: Lung transplantation is hindered by low donor lung utilization rates. Infectious complications are reasons to decline donor grafts due to fear of post-transplant primary graft dysfunction. Mesenchymal stem cells are a promising therapy currently investigated in treating lung injury. Full-term amniotic fluid-derived lung-specific mesenchymal stem cell treatment may regenerate damaged lu

System reliability accounting for corrosion-induced degradation over time

The remaining lifetime of concrete structures subjected to chloride-induced corrosion has been studied in many papers. However, few studies so far consider explicitly experiences from case studies, jointly several corrosion mechanisms and a system perspective. This paper introduces a methodology to evaluate the time-dependent system reliability for concrete bridges subjected to reinforcement corro

Exploring the accessibility of primary health care data in Europe's COVID-19 response: developing key indicators for managing future pandemics (Eurodata study)

Background: Primary Health Care (PHC) plays a crucial role in managing the COVID-19 pandemic, with only 8% of cases requiring hospitalization. However, PHC COVID-19 data often goes unnoticed on European government dashboards and in media discussions. This project aims to examine official information on PHC patient care during the COVID-19 pandemic in Europe, with specific objectives: (1) Describe

Reservoir-excess pressure parameters are independently associated with NT-proBNP in older adults

AIMS: Parameters derived from reservoir-excess pressure analysis have been demonstrated to predict cardiovascular events. Thus, altered reservoir-excess pressure parameters could have a detrimental effect on highly-perfused organs like the heart. We aimed to cross-sectionally determine whether reservoir-excess pressure parameters were associated with N-terminal pro-brain-type natriuretic peptide (

STEMI, Revascularization, and Peak Troponin by Adverse Pregnancy Outcomes in Women With Myocardial Infarction

BACKGROUND: Women with a history of adverse pregnancy outcomes have a higher risk of coronary heart disease. Emerging evidence suggests that women with a history of preeclampsia have a different pattern of overall coronary atherosclerosis and that they at the time of myocardial infarction (MI) more frequently present with ST-segment elevation MI (STEMI) compared to women with no such history.OBJEC

Discovery of a dormant 33 solar-mass black hole in pre-release Gaia astrometry

Context. Gravitational waves from black-hole (BH) merging events have revealed a population of extra-galactic BHs residing in short-period binaries with masses that are higher than expected based on most stellar evolution models-And also higher than known stellar-origin black holes in our Galaxy. It has been proposed that those high-mass BHs are the remnants of massive metal-poor stars. Aims. Gaia

Economic Organizations and the Transformation Towards Degrowth

Degrowth seeks to achieve a sustainable society in the future. It implies overcoming capitalist norms and structures. Economic organizations have found little attention in degrowth scholarship. The existing literature focuses on degrowth compatibility without the wider structural and societal consideration that degrowth implies. Further, it is riddled with incoherences, such as a supposed compatib

Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns

Background: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder where pathophysiological changes begin decades before the onset of clinical symptoms. Analysis of brain atrophy patterns using structural MRI and multivariate data analysis are an effective tool in identifying patients with subjective cognitive decline (SCD) at higher risk of progression to AD dementia. Atrophy patter

Prevalence of diabetes and hospitalization due to poor glycemic control in people with bladder cancer or renal cell carcinoma in Sweden

Background: Bladder cancer (BC) and Renal cell carcinoma (RCC) are the most common urogenital cancers among both sexes, with a yearly global incidence of around 500 000 each. Both BC and RCC have been linked to diabetes. Poor glycemic control (malglycemia) is a serious consequence of diabetes and a possible consequence of systemic treatments used in BC and RCC. The objective of this study was to i

The predictive value of cardiovascular outcomes and mortality assessed by the C-reactive protein to albumin ratio in the UK Biobank

Background: The C-reactive protein/albumin ratio (CAR) seems to mirror disease severity and prognosis in several acute disorders particularly in elderly patients, yet less is known about if CAR is superior to C-reactive protein (CRP) in the general population. Methods: Prospective study design on the UK Biobank, where serum samples of CRP and Albumin were used. Cox regression analyses were conduct

Thrombospondin-4 deletion does not exacerbate muscular dystrophy in β-sarcoglycan-deficient and laminin α2 chain-deficient mice

Muscular dystrophy is a group of genetic disorders that lead to muscle wasting and loss of muscle function. Identifying genetic modifiers that alleviate symptoms or enhance the severity of a primary disease helps to understand mechanisms behind disease pathology and facilitates discovery of molecular targets for therapy. Several muscular dystrophies are caused by genetic defects in the components

Vegetation resistance to increasing aridity when crossing thresholds depends on local environmental conditions in global drylands

The crossing of aridity thresholds triggers abrupt changes in multiple functional and structural ecosystem attributes across global drylands. While we understand the consequences associated with aridity thresholds, the key factors influencing dryland vegetation resistance when crossing them remain unclear. Here, we used field observations from 58 dryland sites across five continents and satellite

Unveiling the drivers of atmospheric methane variability in Iran : A 20-year exploration using spatiotemporal modeling and machine learning

Understanding the factors controlling spatial and temporal variability of atmospheric methane concentration (XCH4) is crucial for mitigating its impacts and implementing emission reduction strategies. This study comprehensively investigates XCH4 and its driving factors (environmental, meteorological, and anthropogenic activity) across Iran over 20 years, from 2003 to 2022. It combines multi-source

Fast Relative Pose Estimation using Relative Depth

In this paper, we revisit the problem of estimating the relative pose from a sparse set of point-correspondences. For each point-correspondence we also estimate the relative depth, i.e. the relative distance to the scene point in the two images. This yields an additional constraint, allowing us to use fewer matches in RANSAC to generate the pose candidates. In the paper we propose two novel minima

JASMINE: Near-infrared astrometry and time-series photometry science

The Japan Astrometry Satellite Mission for INfrared Exploration (JASMINE) is a planned M-class science space mission by the Institute of Space and Astronautical Science, the Japan Aerospace Exploration Agency. JASMINE has two main science goals. One is Galactic archaeology with a Galactic Center survey, which aims to reveal the Milky Way's central core structure and formation history from Gaia-lev

Ett helt vidöppet tillstånd : Gurlesk existentialism i Mare Kandres Bübins unge och Aliide, Aliide

This article examines the combination of gurlesque aesthetics and existentialist themes of anxiety in Mare Kandre’s Bübins unge (1987) and Aliide, Aliide (1991). My ambition is to enable a deeper understanding of what I call “the Dark Girlhood”, that is, the existential pain that Kandre’s female characters constantly seem to experience. While previous readings take the social conditions of the cha

Optical Diagnostics in Energy Conversion Processes

This thesis presents development in optical diagnostics for studies of energy conversion processes. Work has been done in characterization of electrode wear in spark plugs, multi-species high-speed tomographic laser-induced fluorescence, high-speed diagnostics in lab-scale gas turbine burners, and surface temperature measurements on gas turbine burner injection nozzles.A new method of monitoring e

Artificial intelligence and radiologists in prostate cancer detection on MRI (PI-CAI): an international, paired, non-inferiority, confirmatory study

Background: Artificial intelligence (AI) systems can potentially aid the diagnostic pathway of prostate cancer by alleviating the increasing workload, preventing overdiagnosis, and reducing the dependence on experienced radiologists. We aimed to investigate the performance of AI systems at detecting clinically significant prostate cancer on MRI in comparison with radiologists using the Prostate Im