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Joint inhibition of mitochondrial complex IV and alternative oxidase by genetic or chemical means represses chloroplast transcription in Arabidopsis

Changes in the functional state of mitochondria have profound effects on other cellular compartments. Genome-wide expression analysis of Arabidopsis rps10 mutants with an RNAi-silenced expression of mitoribosomal S10 protein has revealed extensive transcriptional reprogramming. A meta-analysis comparing expression datasets of 25 mitochondrial perturbations showed a high similarity of the aox1a:rpo

Retrograde signals from endosymbiotic organelles : A common control principle in eukaryotic cells

Endosymbiotic organelles of eukaryotic cells, the plastids, including chloroplasts and mitochondria, are highly integrated into cellular signalling networks. In both heterotrophic and autotrophic organisms, plastids and/or mitochondria require extensive organelle-to-nucleus communication in order to establish a coordinated expression of their own genomes with the nuclear genome, which encodes the

Elucidating failure mechanisms in human femurs during a fall to the side using bilateral digital image correlation

An improved understanding of the mechanical properties of human femurs is a milestone towards a more accurate assessment of fracture risk. Digital image correlation (DIC) has recently been adopted to provide full-field strain measurements during mechanical testing of femurs. However, it has typically been used to measure strains on the anterior side of the femur, whereas in both single-leg-stance

Survival of Patients With Angina Pectoris Undergoing Percutaneous Coronary Intervention With Intracoronary Pressure Wire Guidance

Background: Intracoronary pressure wire measurement of fractional flow reserve (FFR) provides decision-making guidance during percutaneous coronary intervention (PCI). However, limited data exist on the effect of FFR on long-term clinical outcomes in patients with stable angina pectoris. Objectives: The purpose of this study was to determine the association between the usage of FFR and all-cause m

Electrocatalytic proton-reduction behaviour of telluride-capped triiron clusters : tuning of overpotentials and stabilization of redox states relative to lighter chalcogenide analogues

Reaction of [Fe3(CO)9(µ3-Te)2] (1) with the corresponding phosphine has been used to prepare the phosphine-substituted tellurium-capped triiron clusters [Fe3(CO)9(µ3-Te)2(PPh3)] (2), [Fe3(CO)8(µ3-Te)2(PPh3)] (3) and [Fe3(CO)7(µ3-Te)2(µ-R2PXPR2)] (X = CH2, R = Ph (4), Cy (5); X = NPri, R = Ph (6)). The directly related cluster [Fe3(CO)7(µ3-CO)(µ3-Te)(µ-dppm)] (7) was isolated from the reaction of [

Photocatalytic Degradation of Bacteriophages Evidenced by Atomic Force Microscopy

Methods to supply fresh water are becoming increasingly critical as the world population continues to grow. Small-diameter hazardous microbes such as viruses (20-100 nm diameter) can be filtered by size exclusion, but in this approach the filters are fouled. Thus, in our research, we are investigating an approach in which filters will be reusable. When exposed to ultraviolet (UV) illumination, tit

Physics of viral infectivity : Matching genome length with capsid size

In this work, we review recent advances in the field of physical virology, presenting both experimental and theoretical studies on the physical properties of viruses. We focus on the double-stranded DNA (dsDNA) bacteriophages as model systems for all of the dsDNA viruses both prokaryotic and eukaryotic. Recent studies demonstrate that the DNA packaged into many dsDNA viral capsids is highly pressu

Short-term Revision Risk of Patellofemoral Arthroplasty Is High : An Analysis from Eight Large Arthroplasty Registries

BACKGROUND: Patellofemoral arthroplasty (PFA) is one option for the treatment of isolated patellofemoral osteoarthritis, but there are limited data regarding the procedure and results. Because isolated patellofemoral arthritis is relatively uncommon, available case series generally are small, and even within national registries, sample sizes are limited. Combining data from multiple registries may

The late stage of Parkinson's –results of a large multinational study on motor and non-motor complications

Introduction: There is little information on the late stages of parkinsonism. Methods: We conducted a multicentre study in 692 patients with late stage parkinsonism in six European countries. Inclusion criteria were disease duration of ≥7 years and either Hoehn and Yahr stage ≥4 or Schwab and England score of 50 or less. Results: Average disease duration was 15.4 (SD 7.7) years and mean total UPDR

Dynamic decision-making of airline pilots in low-fidelity simulation

Dynamic decision-making in aviation involves complex problem solving in a dynamic environment characterized by goal conflicts and time constrains. Training mostly focuses on testing domain-specific knowledge and skills that may result in context-specific rather than general problem-solving skills. A low-fidelity decision-making simulation may favour the understanding of the decision process rather

Impact of UV irradiation at full scale on bacterial communities in drinking water

Water in a full-scale drinking water treatment plant was irradiated with ultraviolet (UV) doses of 250, 400, and 600 J/m2, and the effect on bacterial communities investigated using 16s rRNA gene amplicon sequencing, heterotrophic plate counts (HPCs), coliform, and Escherichia coli counts. The bacteria in the irradiated water were also analyzed following storage for 6 days at 7 °C, to approximate

Electron Transfer Mediated by Iron Carbonyl Clusters Enhance Light-Driven Hydrogen Evolution in Water by Quantum Dots

Photocatalytic water splitting has become a promising strategy for converting solar energy into clean and carbon-neutral solar fuels in a low-cost and environmentally benign way. Hydrogen gas is such a potential solar fuel/energy carrier. In a classical artificial photosynthetic system, a photosensitizer is generally associated with a co-catalyst to convert photogenerated charge into (a) chemical

Explaining prevalence, diversity and host specificity in a community of avian haemosporidian parasites

Many hypotheses attempt to explain parasite–host associations, but rarely are they examined together in a single community. For hosts, key traits are the proportion of infected individuals (prevalence) and the diversity of parasites infecting them. A key parasite trait is host specificity, ranging from specialists infecting one or a few closely related species to generalists infecting many species

Daylighting and Electric Lighting Integration in the Retail Sector : A Case Study of the IKEA Kaarst Store

The retail sector represents 11% of the GDP and employs 15% of the workforce in the European Union. To tackle growth of e-commerce, physical retail stores need to be reviewed; both to decrease operating costs, increase productivity and to make the shopping experience more appealing. Energy use for lighting accounts for 50% of the total energy use in non-food retail stores, which is consumed primar

Universiteten och de juridiska fakulteterna som remissinstanser

Kraven på beredning av lagstiftning är en central del i det svenska konstitutionella systemet. I ett större perspektiv kan man se dessa krav som ett uttryck för en mer allmän offentligrättslig princip om beredning av beslut. Mot denna bakgrund behandlar artikeln universitetens och de juridiska fakulteternas roll i lagberedningen som remissinstanser. Utifrån författarens erfarenheter lämnas några s