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CART Regulates Islet Hormone Secretion and Is Expressed in the {beta}-Cells of Type 2 Diabetic Rats.
Survival of mammalian cells exposed to ultrahigh dose rates from a laser-produced plasma x-ray source
PURPOSE: To determine whether intense laser-produced x rays have an increased radiation hazard. MATERIALS AND METHODS: Mammalian cells were exposed to x rays from a laser-produced plasma that produced ultrahigh peak absorbed dose rates, up to a factor of 10(10) higher than those produced by conventional x rays used in imaging. The cell survival was studied as a function of the absorbed dose. The s
Association between exposure to persistent organohalogen pollutants and epididymal and accessory sex gland function: Multicentre study in Inuit and European populations.
Early parasympathetic neuropathy associated with elevated fasting plasma C-peptide concentrations and late parasympathetic neuropathy with hyperglycaemia and other microvascular complications.
Hur dör djur?
From reconciliation to coexistence
The problem of estimating wind drift in migrating birds
Whether migrating birds compensate for wind drift or not is a fundamental question in bird migration research. The procedures to demonstrate and quantitatively estimate wind drift or compensation are fraught with difficulties and pitfalls. In this paper, we evaluate four methods that have been used in several studies over the past decades. We evaluate the methods by analysing a model migratory mov
Ett brännglas för tidens strålar : striden om Torgny Segerstedts docentur 1903
Popular Abstract in Swedish Torgny Segerstedt, den kände chefredaktören för Göteborgs Handels- och Sjöfartstidning, hade utkämpat strider före nazismens tid. Som ung kallades han till docent till Lund på en underkänd avhandling. Disputationen hade ägt rum i maj 1903 vid den teologiska fakulteten i Uppsala. Efter underkännandet beslöt alltså den teologiska fakulteten i Lund att kalla Segerstedt tilOn 1st September 1903, the Faculty of Theology at the University of Lund took the decision to appoint Torgny Segerstedt as a senior lecturer in spite of his failed doctoral dissertation. The public defence of his thesis had taken place on 28th May in the same year before the Faculty of Theology at Uppsala. It was thus after his failure that the Faculty at Lund nevertheless decided to invite him to
The stars of the Galactic center
We consider the origin of the so-called S stars orbiting the supermassive black hole at the very center of the Galaxy. These are usually assumed to be massive main-sequence stars. We argue instead that they are the remnants of low-to-intermediate mass red giants that have been scattered into near-radial orbits and tidally stripped as they approach the central black hole. Such stars retain only low
Lysophosphatidic Acid Binds to and Activates GPR92, a G Protein-Coupled Receptor Highly Expressed in Gastrointestinal Lymphocytes
Here, the ligand binding, activation, and tissue distribution of the orphan G protein-coupled receptor (GPCR) GPR92 were studied. GPR92 binds and is activated by compounds based on the lysophosphatidic acid (LPA) backbone. The binding of LPA to GPR92 was of high affinity (K(D) = 6.4 +/- 0.9 nM) and led to an increase in both phosphoinositide hydrolysis and cAMP production. GPR92 is atypical in tha
A focused antibody library for improved hapten recognition
The topography of the antigen-binding site as well as the number and the positioning of the antigen contact residues are strongly correlated with the size of the antigen with which the antibody interacts. On the basis of these considerations, we have designed a focused scFv repertoire biased for haptens, designated the cavity library. The hapten-specific scFv, FITC8, was used as a scaffold for lib
A-kassa på deltid: ett ständigt problem inom arbetslöshetsförsäkringen
Non-invasive assessment of atrial refractoriness during atrial fibrillation
Fler amerikaner utan sjukförsäkring
NADH oxidation using carbonaceous electrodes modified with dibenzo-dithia-diazapentacene
The electrochemical and the electrocatalytic behavior for NADH oxidation of a newly synthesized phenothiazine derivative, 16H,18H-dibenzo[c,1]-7,9-dithia-16,18-diazapentacene (DDDP), adsorbed on solid spectrographic graphite and on graphite powder or on zirconium phosphate (ZP), both entrapped in carbon paste, were compared. Experiments using cyclic voltammetry and a rotating disk electrode, perfo
Whey protein adsorption onto steel surfaces - effect of temperature, flow rate, residence time and aggregation
Whey protein adsorption on stainless steel surfaces was investigated by in situ ellipsometry under well-defined flow conditions and protein solution residence times. The size distribution in solution of the protein aggregates formed under the same conditions was determined by dynamic light scattering. The adsorption was performed at 72 degrees C and 85 degrees C which is below and above the unfold
Long-term outcome in patients with suspected normal pressure hydrocephalus
OBJECTIVE: To evaluate the outcome of patients with suspected normal pressure hydrocephalus at 6 months and 5 years after shunt Surgery. METHODS: Seventy-five patients (mean age, 72.5 +/- 9 yr), with normal pressure hydrocephalus symptoms were included. Fifty-four patients with positive lumbar infusion and/or cerebrospinal fluid tap tests received a cerebrospinal fluid shunt, whereas 21 patients w
Excitation of P-modes in the sun and stars
P-mode oscillations in the Sun and stars are excited stochasticly by Reynolds stress and entropy fluctuations produced by convection in their outer envelopes. The excitation increases with increasing effective temperature (until envelope convection ceases in the F stars) and also increases with decreasing gravity.
Knee kinematics and kinetics in former soccer players with a 16-years-old ACL injury - The effects of twelve weeks of knee-specific training
Background: Training of neuromuscular control has become increasingly important and plays a major role in rehabilitation of subjects with an injury to the anterior cruciate ligament (ACL). Little is known, however, of the influence of this training on knee stiffness during loading. Increased knee stiffness occurs as a loading strategy of ACL-injured subjects and is associated with increased joint