Inference of antibody gene repertoires using transcriptome data has emerged as an alternative approach to the complex process of sequencing of adaptive immune receptor germline gene loci. The diversity introduced during rearrangement of immunoglobulin heavy chain variable (IGHV), diversity, and joining genes has however been identified as potentially affecting inference specificity. In this study,

In this communication, the AuIn 1:1 phase (Naturwissenschaften, 1953, 40, 437, DOI: 10.1007/BF00590353), and its ordering behavior at various temperatures is investigated. To enable the growth of a X-ray suitable specimen, a tempering routine was established by the interpretation of a differential scanning calorimetry (DSC) study. In this way, good quality single crystals were grown and measured a

Blood samples are widely used for PCR-based DNA analysis in fields such as diagnosis of infectious diseases, cancer diagnostics, and forensic genetics. In this study, the mechanisms behind blood-induced PCR inhibition were evaluated by use of whole blood as well as known PCR-inhibitory molecules in both digital PCR and real-time PCR. Also, electrophoretic mobility shift assay was applied to invest

Remote patient monitoring should reduce mortality rates, improve care, and reduce costs. We present an overview of the available technologies for the remote monitoring of chronic obstructive pulmonary disease (COPD) patients, together with the most important medical information regarding COPD in a language that is adapted for engineers. Our aim is to bridge the gap between the technical and medica

Physiotherapists are facing complex health challenges in the treatment of persons suffering from long-lasting musculoskeletal disorders and mental health problems. Basic Body Awareness Therapy (BBAT) is a physiotherapy approach within the movement awareness domain developed to bridge physical, mental, and relational health challenges. The purpose of this study was to reach a consensus on core phen

The study investigates inequalities in access to social capital based on social class origin and immigration background and examines the role of transnational ties in explaining these differences. Social capital is measured with a position generator methodology that separates between national and transnational contacts in a sample of young adults in Sweden with three parental backgrounds: at least

Background. Continuous experimentation (CE) has recently emerged as an established industry practice and as a research subject. Our aim is to study the application of CE and A/B testing in various industrial contexts. Objective. We wanted to investigate whether CE is used in different sectors of industry, by how it is reported in academic studies. We also wanted to explore the main topics research

Direct conversion of human somatic cells to induced neurons (iNs), using lineage-specific transcription factors has opened new opportunities for cell therapy in a number of neurological diseases, including epilepsy. In most severe cases of epilepsy, seizures often originate in the hippocampus, where populations of inhibitory interneurons degenerate. Thus, iNs could be of potential use to replace t

The human population displays wide variety in demographic history, ancestry, content of DNA derived from hominins or ancient populations, adaptation, traits, copy number variation, drug response, and more. These polymorphisms are of broad interest to population geneticists, forensics investigators, and medical professionals. Historically, much of that knowledge was gained from population survey pr

The Internet of Things (IoT) paradigm brings an opportunity for advanced Demand Response (DR) solutions. It enables visibility and control on the various appliances that may consume, store or generate energy within a home. It has been shown that a centralized control on the appliances of a set of households leads to efficient DR mechanisms; unfortunately, such solutions raise privacy and scalabili

Schemes to promote sustainable forest management have increasingly focused on addressing widespread informalities in timber production, based on the presumed links between formalisation, the maintenance of forest cover and local welfare. This trend is typified by the EU Forest Law Enforcement, Governance and Trade (FLEGT) initiative and associated Voluntary Partnership Agreements (VPA) aimed at er

We identify, through a change of variables, solution operators for evolution equations with generators given by certain simple first-order differential operators acting on Fock spaces. This analysis applies, through unitary equivalence, to a broad class of supersymmetric quadratic multiplication-differentiation operators acting on L2.Rn/ which includes the elliptic and weakly elliptic quadratic op

Biohythane is a hydrogen-methane blend with hydrogen concentration between 10 and 30% v/v. It can be produced from different organic substrates by two sequential anaerobic stages: a dark fermentation step followed by a second an anaerobic digestion step, for hydrogen and methane production, respectively. The advantages of this blend compared to either hydrogen or methane, as separate biofuels, are

Over the last decades, the Western world has seen millions of relatively well-paid manufacturing jobs disappear. Some have shifted to low-income countries, while other have been permanently lost due the introduction of labor-saving technologies. Concurrently, many comparatively low-wage jobs have been created in services, for example in fast food and retailing. This paper uses a dynamic panel of 2

Drawing on contemporary publications in German and Swedish/Scandinavian journals and biographies as well as conference proceedings of the German Society of Urology (DGU), this paper examines the Swedish impressions of the 1929 DGU meeting in Munich. It focusses on why the Swedish delegates visited the congress and how they evaluated their congress experiences for their Scandinavian peers. Finally,

In 2007 Finland changed ownership rights to inventions from its employees - "the professor's privilege" - to universities. We investigate how this change affected academic patenting using new data on inventors and patenting in Finland for the period 1995-2010. Matched sample panel data regressions using difference-in-differences show that patenting by individuals dropped by at least 29 percent aft

This communication proposes to use the 1-λ resonant mode of slot radiator with single feeding for bandwidth enhancement. The impedance of a simple slot radiator is studied using computer simulation. Since operating the slot radiator in the 1-λ resonant mode requires a longer slot length, a large square slot is used at both ends of the slot to reduce the required slot length. The results of the stu