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Introduction to 'The Spaces of Utopia and Dystopia'
Optimizing transurethral microwave thermotherapy: a model for studying power, blood flow, temperature variations and tissue destruction - Reply
Application of synthetic peptides for detection of anti-citrullinated peptide antibodies.
Anti-citrullinated protein antibodies (ACPAs) are a hallmark of rheumatoid arthritis (RA) and represent an important tool for the serological diagnosis of RA. In this study, we describe ACPA reactivity to overlapping citrullinated Epstein-Barr virus nuclear antigen-1 (EBNA-1)-derived peptides and analyze their potential as substrates for ACPA detection by streptavidin capture enzyme-linked immunos
U-2973, a novel B-cell line established from a patient with a mature B-cell leukemia displaying concurrent t(14;18) and MYC translocation to a non-IG gene partner.
B-cell lymphomas/leukemias with simultaneous t(14;18)(q32;q21) and MYC rearrangements have recently been shown to constitute a separate diagnostic entity, presenting with a rapid clinical course and a very poor prognosis. We describe the establishment of an Epstein-Barr virus negative cell line, designated U-2973, from a male patient with a de novo aggressive B-cell lymphoma/leukemia and very high
Alpha-Synuclein Produces Early Behavioral Alterations Via Striatal Cholinergic Synaptic Dysfunction by Interacting with GluN2D N-Methyl-D-Aspartate Receptor Subunit.
Advanced Parkinson's disease (PD) is characterized by massive degeneration of nigral dopaminergic neurons, dramatic motor and cognitive alterations, and presence of nigral Lewy bodies, whose main constituent is α-synuclein (α-syn). However, the synaptic mechanisms underlying behavioral and motor effects induced by early selective overexpression of nigral α-syn are still a matter of debate.
Full-field electroretinography and marked variability in clinical phenotype of Alström syndrome.
OBJECTIVES: To characterize the clinical phenotype and to study the course of disease in patients with Alström syndrome, with an emphasis on retinal function assessed with full-field electroretinography (ERG). METHODS: Three age- and sex-matched patients with Alström syndrome were selected from our retinitis pigmentosa register for repeated ophthalmologic examinations that included tests for color
Acute type B dissection: endovascular repair or open surgery?
Acute dissection of the descending thoracic aorta is often a life threatening disease. If complicated by rupture or organ malperfusion, immediate invasive treatment is mandatory to prevent death. Open surgery by interposition grafting or visceral fenestration is complex and associated with high morbidity and mortality. The introduction of endovascular stentgraft repair has offered a minimally inva
Liposuction May Reduce Pain in Dercum's Disease (Adiposis Dolorosa).
Objective. The aim of this prospective study is to assess the effect of liposuction on the pain experienced by women with Dercum's disease (adiposis dolorosa). Design. Pain was examined preoperatively and at 3 months, and 1, 2, 3, and 5 years after liposuction. The subjective pain sensation was evaluated with a visual analog scale and number of words chosen, and the objective pain sensation with t
Prediction of glaucomatous visual field loss by extrapolation of linear trends.
OBJECTIVE: To investigate how well short-term progression rates can predict long-term visual field outcomes in patients with glaucoma. METHODS: We calculated visual field rates of progression using linear regression analysis of the Visual Field Index (VFI) for 100 consecutive patients with glaucoma having 10 or more Swedish Interactive Thresholding Algorithm standard field tests. Final VFI was pre
Intervention for hazardous alcohol use and high level of stress in university freshmen A comparison between an intervention and a control University.
BACKGROUND: The first year of university studies is associated with increased levels of alcohol drinking and stress. This study examines the one-year outcome of both primary and secondary interventions of one alcohol programme and one stress intervention programme at an intervention university in comparison with a control university. METHODS: At the intervention university all freshmen were offere
Platelet-Derived CD40L (CD154) Mediates Neutrophil Upregulation of Mac-1 and Recruitment in Septic Lung Injury.
OBJECTIVE:: To define the role of CD40L in abdominal sepsis. BACKGROUND:: Platelets promote sepsis-induced pulmonary recruitment of neutrophils. However, the identity of the platelet-derived molecule regulating neutrophil infiltration is not known. The hypothesis of the present study was that platelet-derived CD40L might be responsible for platelet-mediated activation and accumulation of neutrophi
High harmonic generation at long wavelengths
High harmonic radiation spectra up to 19th order in alkali metal vapors excited by an intense, picosecond mid-infrared (3 -4 mu m) laser are reported and compared to theory. The strong-field dynamics in the alkali metal atoms exhibit significant differences from all previously studied systems due to the strong coupling between their ground and first excited states.
Intermarriage, Value Context and Union Dissolution: Sweden 1990-2005
Differential gene expression analysis of placentas with increased vascular resistance and pre-eclampsia using whole-genome microarrays.
Pre-eclampsia is a pregnancy complication characterized by hypertension and proteinuria. There are several factors associated with an increased risk of developing pre-eclampsia, one of which is increased uterine artery resistance, referred to as "notching". However, some women do not progress into pre-eclampsia whereas others may have a higher risk of doing so. The placenta, central in pre-eclamps
Treatment of a benign colorectal anastomotic stricture with a biodegradable stent.
Glutamatergic pathways as a target for the treatment of dyskinesias in Parkinson's disease.
PD (Parkinson's disease) is characterized by some typical motor features that are caused by striatal dopamine depletion and respond well to dopamine-replacement therapy with L-dopa. Unfortunately, the majority of PD patients treated with L-dopa develop abnormal involuntary movements (dyskinesias) within a few years. The mechanisms underlying the development of LIDs (L-dopa-induced dyskinesias) inv
Long-term detrimental consequences of the onset of type 1 diabetes on annual earnings-evidence from annual registry data in 1990-2005.
AIMS/HYPOTHESIS: Young adults in the early stages of their participation in the labour market may be particularly vulnerable to the effects of onset of a chronic disease. Our aim was to quantify the consequences of the onset of type 1 diabetes in young adults on annual earnings, using individual-level longitudinal data before and after the onset of diabetes. METHODS: The Econ-DISS database contain