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EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases

The most common diseases affecting middle-aged and elderly subjects in industrialized countries are multigenetic and lifestyle related. Several attempts have been made to study interactions between genes and lifestyle factors, but most such studies lack the power to examine interactions between several genes and several lifestyle components. The primary objective of the EpiHealth cohort study is t

Breaking bad habits by education : smoking dynamics among Swedish women

In a dynamic Two-Part Model (2PM), we find the effect of previous smoking on the participation decision to be decreasing with education among Swedish women, i.e. more educated are less state dependent. However, we do not find an analogous effect of education on the conditional intensity of consumption.

N-terminal pro-atrial natriuretic peptide response to acute exercise in depressed patients and healthy controls

Background: The dysfunction of hypothalamic-pituitary-adrenal (HPA) axis in major depression includes hyperactivity and reduced feedback inhibition. Atrial natriuretic peptide (ANP) is able to reduce the HPA-axis response to stress and has an anxiolytic effect in rodents and humans. We hypothesized that patients with depression would have an attenuated N-terminal proANP (NT-proANP) response to acu

Enhanced Production of Direct Photons in Au plus Au Collisions at root s(NN)=200 GeV and Implications for the Initial Temperature

The production of e(+)e(-) pairs for m(e+e-) < 0.3 GeV/c(2) and 1< p(T) < 5 GeV/c is measured in p + p and Au + Au collisions at root s(NN) = 200 GeV. An enhanced yield above hadronic sources is observed. Treating the excess as photon internal conversions, the invariant yield of direct photons is deduced. In central Au + Au collisions, the excess of the direct photon yield over p + p is exponentia

Historical TOC concentration minima during peak sulfur deposition in two Swedish lakes

Decadal-scale variations in total organic carbon (TOC) concentration in lake water since AD1200 in two small lakes in southern Sweden were reconstructed based on visible-near-infrared spectroscopy (VNIRS) of their recent sediment successions. In order to assess the impacts of local land-use changes, regional variations in sulfur, and nitrogen deposition and climate variations on the inferred chang

The Swansong of the Mandarins : Humboldt’s Idea of the University in Early Post-War Germany

In the wake of the Second World War, Germany saw an intensive debate about the idea of the university and its future role in society. All were agreed that the country’s universities had to be revitalized after the ravages of Nazism, but the question was what weight should be given to the classical German heritage, and the Humboldtian tradition in particular. The mandarins, the older humanist schol

Polychaete palaeoecology in an early Late Ordovician marine astrobleme of Sweden

The post-impact Dalby Limestone (Kulcruse; Upper Ordovician) of the Tvaren crater, southeastern Sweden, has been analysed with regards to polychaetes, as represented by scolecodonts. A palaeoecological succession is observed in the Tvaren-2 drill core sequence, as the vacant ecospace was successively filled by a range of benthonic, nektonic and planktonic organisms. Scolecodonts belong to the firs

Are technology myths stalling aviation climate policy?

Emissions from aviation will continue to increase in the future, in contradiction of global climate policy objectives. Yet, airlines and airline organisations suggest that aviation will become climatically sustainable. This paper investigates this paradox by reviewing fuel-efficiency gains since the 1960s in comparison to aviation growth, and by linking these results to technology discourses, base

Framed School : Frame Factors, Frames and the Dynamics of Social Interaction in School

This paper aims to show how the Goffman frame perspective can be used in an analysis of school and education and how it can be combined, in such analysis, with the frame factor perspective. The latter emphasizes factors that are determined outside the teaching process, while the former stresses how actors organize their experiences and define shared situations. In this light, an analysis of framin

The formation of Staphylococcus aureus enterotoxin in food environments and advances in risk assessment.

The recent finding that the formation of staphylococcal enterotoxins in food is very different from that in cultures of pure Staphylococcus aureus sheds new light on, and brings into question, traditional microbial risk assessment methods based on planktonic liquid cultures. In fact, most bacteria in food appear to be associated with surfaces or tissues in various ways, and interaction with other

Testing for stock return predictability in a large Chinese panel

This paper proposes a simple panel data test for stock return predictability that is flexible enough to accommodate three key salient features of the data, namely, predictor persistency and endogeneity, and cross-sectional dependence. Using a large panel of Chinese stock market data comprising more than one million observations, we show that most financial and macroeconomic predictors are in fact

Small Distal Muscles and Balance Predict Survival in End-Stage Renal Disease.

Background/Aims: Survival for patients on renal replacement therapy (RRT) has been shown to correlate to the level of physical activity and exercise capacity. We examined whether composite measures of functional status at the start of RRT predict survival. Methods: In this retrospective study, the same physiotherapist, using a standardized battery of tests for functional status, tested 134 patient

Violaxanthin de-epoxidase disulphides and their role in activity and thermal stability.

Violaxanthin de-epoxidase (VDE) catalyses the conversion of violaxanthin to zeaxanthin at the lumen side of the thylakoids during exposure to intense light. VDE consists of a cysteine-rich N-terminal domain, a lipocalin-like domain and a negatively charged C-terminal domain. That the cysteines are important for the activity of VDE is well known, but in what way is less understood. In this study, w

Optimism and subjective well-being: Affectivity plays a secondary role in the relationship between optimism and global life satisfaction in the middle-aged women. Longitudinal and cross-cultural findings

The focus of the present study lies on optimism and its relationships to the components of subjective well-being, i.e. global life satisfaction, positive affect and negative affect. We investigated the direct and indirect (via affectivity) effects of optimism on global life satisfaction in the Swedish middle-aged women at two time points (age 43 and 49), and in the Lithuanian middle-aged women. Fo

Investigation of a simple approach to predict rainscreen wall ventilation rates for hygrothermal simulation purposes

Hygrothermal simulation programs are commonly used by design engineers to analyse moisture performance of building envelopes. For ventilated assemblies, programs typically require the user to enter cavity ventilation rates. If such input data are not prepared on physical grounds, it can impair the quality of the simulation results. In earlier papers: (1) estimations of ventilation rates in experim

Look at yourself!: Visual perspective influences moral judgment through level of mental construal

Previous research (Libby et al., 2009) has established that a third-person (outside) visual perspective elicits more abstract processing than a first-person (inside) perspective. Because many moral principles constitute abstract psychological constructs, we predicted that they should weigh more heavily when people adopt a third-person visual perspective. In two experiments we show that a third- (v

Perturbative solution to susceptible-infected-susceptible epidemics on networks.

Herein we provide a closed form perturbative solution to a general M-node network susceptible-infected-susceptible (SIS) model using the transport rates between nodes as a perturbation parameter. We separate the dynamics into a short-time regime and a medium-to-long-time regime. We solve the short-time dynamics of the system and provide a limit before which our explicit, analytical result of the f