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The BCR gene is implicated in the development of Ph-positive leukemia through its fusion with the nonreceptor tyrosine kinase gene ABL. The normal 160 kDa Bcr protein has several functional domains, and recently one specific role for Bcr was established in the regulation of respiratory burst activity in white blood cells. Bcr expression levels are relatively constant throughout mouse development u
Complement deficiencies are probably vastly under-diagnosed within clinical medicine. Judging from a Swedish study of C2 deficiency, a deficiency with an estimated prevalence of about 1/20,000 in Western countries, less than 10% of the deficiencies of the classical and alternative pathways and the late complement components are identified in Sweden. C1 inhibitor deficiency and deficiencies of MBL
Slave Morality: Theological Perspectives on the Law of Moses. The fusion between the regulations for human relations and behavior on the one hand and worship of and belief in YHWH on the other is the most prominent feature of Biblical Law. The historical background and growth of this characteristic is here investigated and some of its theological implications are scrutinized. Beginning with the la
The purpose of this work is to propose a detailed model for the formation of soot in turbulent reacting flow and to use this model to study a carbon black furnace. The model is based on a combination of a detailed reaction mechanism to calculate the gas phase chemistry, a detailed kinetic soot model based on the method of moments, and the joint composition probability density function (PDF) of the
We recently established that fibroblast growth factor (FGF)-1 promotes adipogenesis of primary human preadipocytes (phPA). In the current report, we have characterized the adipogenic effects of FGF-1 in phPA and also in a human PA strain derived from an individual with Simpson-Golabi-Behmel syndrome (SGBS PA), which exhibit an intrinsic capacity to differentiate with high efficiency. In further st
The distribution of 50 species in the south Swedish provinces of Skane (Scania). Halland, Blekinge, Oland and Smaland has been mapped. Many of the species are endemic to southern Scandinavia and some are local endemics within the investigated area. However, there are also several species with a wider North European distribution. Within the area, the number of species shows a regular decline from t
With the introduction of mammographic screening the incidence of ductal carcinoma in situ (DCIS) has increased to 10-15% of all breast cancers. The aim of this study was to investigate whether there were any morphological and cell biological differences between DCIS detected during the pre-screening (n = 39) as opposed to the screening period (n = 120). We could not demonstrate any statistically s
Dihydropyrimidinase (EC 3.5.2.2) is the second enzyme in the reductive pyrimidine-degradation pathway and catalyses the hydrolysis of 5,6-dihydrouracil and 5,6-dihydrothymine to the corresponding N-carbamylated beta-amino acids. The recombinant enzyme from the slime mould Dictyostelium discoideum was overexpressed, purified and crystallized by the vapour-diffusion method. One crystal diffracted to
We have compiled data on the occurrence of a threatened beetle, Osmoderma eremita, in Sweden. The species inhabits tree hollows with wood mould. The data were compiled from field surveys conducted in 1993-2003, using pitfall traps at 401 localities and using wood mould sampling at 104 localities. We have also gone through published data and all larger Swedish museums and registered old records. O.
Rec. diskuterar festskriften som genre i allmänhet, och i synnerhet dessa båda exempel på olika uppläggning, som båda tecknar ett akademiskt vänporträtt och för forskningsfronten framåt. Sedan övergår rec. till att lyfta fram de bidrag som är av särskilt kyrkohistoriskt intresse. Festskriften till Göran Gustafsson avslutas med en värdefull bibliografi
We present a mass transport model based on surface diffusion for metal-particle-assisted nanowire growth. The model explains the common observation that for III/V materials thinner nanowires are longer than thicker ones. We have grown GaP nanowires by metal-organic vapor phase epitaxy and compared our model calculations with the experimental nanowire lengths and radii. Moreover, we demonstrate tha
This paper proposes a new dynamic mode of generating bioanalytical arrays in microfluidic systems, based on ultrasonic trapping of microbeads using acoustic forces in standing waves. Trapping of microbead clusters in an array format within a flow-through device is demonstrated for the first time using a device with three integrated ultrasonic microtransducers. The lateral extension of each trappin
